2024 ICD-10-CM Diagnosis Code T36.5X5

Adverse effect of aminoglycosides

ICD-10-CM Code:
T36.5X5
ICD-10 Code for:
Adverse effect of aminoglycosides
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Injury, poisoning and certain other consequences of external causes
    (S00–T88)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
      (T36-T50)
      • Poisoning by, adverse effect of and underdosing of systemic antibiotics
        (T36)

T36.5X5 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of aminoglycosides. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Adverse effect of aminoglycosides

Non-specific codes like T36.5X5 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for adverse effect of aminoglycosides:

  • Use T36.5X5A for initial encounter - BILLABLE CODE

  • Use T36.5X5D for subsequent encounter - BILLABLE CODE

  • Use T36.5X5S for sequela - BILLABLE CODE

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Adverse reaction to chlorhexidine and/or neomycin
  • Adverse reaction to chlorhexidine and/or neomycin
  • Amikacin adverse reaction
  • Aminoglycosides adverse reaction
  • Antituberculous drug adverse reaction
  • Gentamicin adverse reaction
  • Kanamycin adverse reaction
  • Neomycin adverse reaction
  • Nephropathy induced by aminoglycoside
  • Netilmicin adverse reaction
  • Spectinomycin adverse reaction
  • Streptomycin adverse reaction
  • Tobramycin adverse reaction

Clinical Information

  • Amikacin

    a broad-spectrum antibiotic derived from kanamycin. it is reno- and oto-toxic like the other aminoglycoside antibiotics.
  • Kanamycin Kinase

    a class of enzymes that inactivate aminocyclitol-aminoglycoside antibiotics (aminoglycosides) by regiospecific phosphorylation of the 3' and/or 5' hydroxyl.
  • Dibekacin

    analog of kanamycin with antitubercular as well as broad-spectrum antimicrobial properties.
  • Framycetin

    a component of neomycin that is produced by streptomyces fradiae. on hydrolysis it yields neamine and neobiosamine b. (from merck index, 11th ed)
  • Kanamycin

    antibiotic complex produced by streptomyces kanamyceticus from japanese soil. comprises 3 components: kanamycin a, the major component, and kanamycins b and c, the minor components.
  • Kanamycin Resistance

    nonsusceptibility of bacteria to the antibiotic kanamycin, which can bind to their 70s ribosomes and cause misreading of messenger rna.
  • Netilmicin

    semisynthetic 1-n-ethyl derivative of sisomycin, an aminoglycoside antibiotic with action similar to gentamicin, but less ear and kidney toxicity.
  • Novobiocin

    an antibiotic compound derived from streptomyces niveus. it has a chemical structure similar to coumarin. novobiocin binds to dna gyrase, and blocks adenosine triphosphatase (atpase) activity. (from reynolds, martindale the extra pharmacopoeia, 30th ed, p189)
  • Paromomycin

    an aminoglycoside antibacterial and antiprotozoal agent produced by species of streptomyces.
  • Ribostamycin

    a broad-spectrum antimicrobial isolated from streptomyces ribosifidicus.
  • Sisomicin

    antibiotic produced by micromonospora inyoensis. it is closely related to gentamicin c1a, one of the components of the gentamicin complex (gentamicins).
  • Spectinomycin

    an antibiotic produced by streptomyces spectabilis. it is active against gram-negative bacteria and used for the treatment of gonorrhea.
  • Tobramycin

    an aminoglycoside, broad-spectrum antibiotic produced by streptomyces tenebrarius. it is effective against gram-negative bacteria, especially the pseudomonas species. it is a 10% component of the antibiotic complex, nebramycin, produced by the same species.
  • Tobramycin, Dexamethasone Drug Combination

    a topical preparation of tobramycin and dexamethasone that is used for treating or preventing superficial bacterial infections of the eye.

Coding Guidelines

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of systemic antibiotics (T36). Use the following options for the aplicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Table of Drugs and Chemicals

The code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
(self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
AmikacinT36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
AstromicinT36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
BekanamycinT36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
DibekacinT36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
DihydrostreptomycinT36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
FramycetinT36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
GaramycinT36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
Garamycin
  »ophthalmic preparation
T36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
Garamycin
  »topical NEC
T36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
GentamicinT36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
Gentamicin
  »ophthalmic preparation
T36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
Gentamicin
  »topical NEC
T36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
IsepamicinT36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
KanamycinT36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
KantrexT36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
MicronomicinT36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
MycifradinT36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
Mycifradin
  »topical
T36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
Neomycin (derivatives)T36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
Neomycin (derivatives)
  »with
T36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
Neomycin (derivatives)
  »with
    »bacitracin
T36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
Neomycin (derivatives)
  »with
    »neostigmine
T36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
Neomycin (derivatives)
  »ENT agent
T36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
Neomycin (derivatives)
  »ophthalmic preparation
T36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
Neomycin (derivatives)
  »topical NEC
T36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
NetilmicinT36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
NovobiocinT36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
ParomomycinT36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
RibostamycinT36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
SisomicinT36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
SpectinomycinT36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
StreptoduocinT36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
Streptomycin (derivative)T36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
StreptonivicinT36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
StreptovarycinT36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6
TobramycinT36.5X1T36.5X2T36.5X3T36.5X4T36.5X5T36.5X6

Patient Education


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

What is a drug interaction?

A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as gingko and blood thinners
  • Drugs and medical conditions, such as aspirin and peptic ulcers

Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.

What are side effects?

Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.

What are drug allergies?

Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.

How can I stay safe when taking medicines?

When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.