2026 ICD-10-CM Diagnosis Code T36.3X6AUnderdosing of macrolides, initial encounter

ICD-10-CM CodesS00–T88T36-T50T36

ICD-10-CM T36.3X6A
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

T36.3X6A is a billable ICD-10-CM diagnosis code for underdosing of macrolides, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The code is not accepted as a principal diagnosis by the Medicare Code Editor. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Underdosing of drugs and medicaments, initial encounter.

Code Identity

ICD-10-CM Code
T36.3X6A
Billable Status
Yes — Valid for Submission
Code Describes
Underdosing of macrolides, initial encounter
Short Description
Underdosing of macrolides, initial encounter
Same as the full description in the CMS dataset.
Parent Code
Underdosing of macrolides

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT36Poisoning by, adverse effect of and underdosing of systemic antibiotics
This CodeT36.3X6AUnderdosing of macrolides, initial encounter

Code EditsBilling

Medicare Code Editor checks that affect claim validity for T36.3X6A.

There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Coding GuidelinesGuidance

Underdosing refers to taking less of a medication than is prescribed by a provider or a manufacturer's instruction. Codes for underdosing should never be assigned as principal or first-listed codes. If a patient has a relapse or exacerbation of the medical condition for which the drug is prescribed because of the reduction in dose, then the medical condition itself should be coded.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of systemic antibiotics (T36). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ029
Underdosing of drugs and medicaments, initial encounter
Default principal diagnosis: inpatient No · outpatient No

Clinical InformationClinical

  • Azithromycin

    a semi-synthetic macrolide antibiotic structurally related to erythromycin. it has been used in the treatment of mycobacterium avium intracellulare infections, toxoplasmosis, and cryptosporidiosis.
  • Josamycin

    a macrolide antibiotic from streptomyces narbonensis. the drug has antimicrobial activity against a wide spectrum of pathogens.
  • Kitasamycin

    a macrolide antibiotic produced by streptomyces kitasatoensis. the drug has antimicrobial activity against a wide spectrum of pathogens.
  • Oleandomycin

    antibiotic macrolide produced by streptomyces antibioticus.
  • Pristinamycin

    an antibiotic mixture originally isolated from streptomyces pristinaspiralis. it is a mixture of compounds from streptogramin group a: pristinamycin iia and iib and from streptogramin group b: pristinamycin ia, pristinamycin ib, pristinamycin ic.
  • Streptogramin A

    a specific streptogramin group a antibiotic produced by streptomyces graminofaciens and other bacteria.
  • Streptogramin B

    a specific streptogramin group b antibiotic produced by streptomyces graminofaciens and other bacteria.
  • Roxithromycin

    semisynthetic derivative of erythromycin. it is concentrated by human phagocytes and is bioactive intracellularly. while the drug is active against a wide spectrum of pathogens, it is particularly effective in the treatment of respiratory and genital tract infections.
  • Spiramycin

    a macrolide antibiotic produced by streptomyces ambofaciens. the drug is effective against gram-positive aerobic pathogens, n. gonorrhoeae, and staphylococci. it is used to treat infections caused by bacteria and toxoplasma gondii.
  • Troleandomycin

    a macrolide antibiotic that is similar to erythromycin.

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
AzithromycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
Erythromycin (salts)T36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
Erythromycin (salts)::ophthalmic preparationT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
Erythromycin (salts)::topical NECT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
IlotycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
Ilotycin::ophthalmic preparationT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
Ilotycin::topical NECT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
JosamycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
KitasamycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
MidecamycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
MiokamycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
OleandomycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
PristinamycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
RokitamycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
RoxithromycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
SpiramycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
TAOT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
TriacetyloleandomycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
TroleandomycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6

Patient EducationClinical

Antibiotics

Antibiotics are medicines that fight bacterial infections in people and animals. They work by killing the bacteria or by making it hard for the bacteria to grow and multiply.

The full article covers:

  • What are antibiotics?
  • What do antibiotics treat?
  • Do antibiotics treat viral infections?
  • What are the side effects of antibiotics?
  • Why is it important to take antibiotics only when they're needed?
  • How do I use antibiotics correctly?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T36.3X6A to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
No Map There is no ICD-9 equivalent for this code.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About T36.3X6AOverview

Is T36.3X6A (Underdosing of macrolides) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report underdosing of macrolides, initial encounter on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What does the 7th character A in T36.3X6A mean?

The final character A marks the initial encounter: use it while the patient is receiving active treatment for underdosing of macrolides, such as an emergency visit or first evaluation.

Can T36.3X6A be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because underdosing of macrolides, initial encounter describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.