2024 ICD-10-CM Diagnosis Code T36.3X5

Adverse effect of macrolides

ICD-10-CM Code:
T36.3X5
ICD-10 Code for:
Adverse effect of macrolides
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Injury, poisoning and certain other consequences of external causes
    (S00–T88)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
      (T36-T50)
      • Poisoning by, adverse effect of and underdosing of systemic antibiotics
        (T36)

T36.3X5 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of macrolides. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Adverse effect of macrolides

Non-specific codes like T36.3X5 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for adverse effect of macrolides:

  • Use T36.3X5A for initial encounter - BILLABLE CODE

  • Use T36.3X5D for subsequent encounter - BILLABLE CODE

  • Use T36.3X5S for sequela - BILLABLE CODE

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Adverse reaction to oleandomycin
  • Azithromycin adverse reaction
  • Clarithromycin adverse reaction
  • Erythromycin adverse reaction
  • Macrolide adverse reaction
  • Spiramycin adverse reaction

Clinical Information

  • Azithromycin

    a semi-synthetic macrolide antibiotic structurally related to erythromycin. it has been used in the treatment of mycobacterium avium intracellulare infections, toxoplasmosis, and cryptosporidiosis.
  • Josamycin

    a macrolide antibiotic from streptomyces narbonensis. the drug has antimicrobial activity against a wide spectrum of pathogens.
  • Kitasamycin

    a macrolide antibiotic produced by streptomyces kitasatoensis. the drug has antimicrobial activity against a wide spectrum of pathogens.
  • Oleandomycin

    antibiotic macrolide produced by streptomyces antibioticus.
  • Pristinamycin

    an antibiotic mixture originally isolated from streptomyces pristinaspiralis. it is a mixture of compounds from streptogramin group a: pristinamycin iia and iib and from streptogramin group b: pristinamycin ia, pristinamycin ib, pristinamycin ic.
  • Streptogramin A

    a specific streptogramin group a antibiotic produced by streptomyces graminofaciens and other bacteria.
  • Streptogramin B

    a specific streptogramin group b antibiotic produced by streptomyces graminofaciens and other bacteria.
  • Roxithromycin

    semisynthetic derivative of erythromycin. it is concentrated by human phagocytes and is bioactive intracellularly. while the drug is active against a wide spectrum of pathogens, it is particularly effective in the treatment of respiratory and genital tract infections.
  • Spiramycin

    a macrolide antibiotic produced by streptomyces ambofaciens. the drug is effective against gram-positive aerobic pathogens, n. gonorrhoeae, and staphylococci. it is used to treat infections caused by bacteria and toxoplasma gondii.
  • Troleandomycin

    a macrolide antibiotic that is similar to erythromycin.

Coding Guidelines

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of systemic antibiotics (T36). Use the following options for the aplicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Table of Drugs and Chemicals

The code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
(self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
AzithromycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
Erythromycin (salts)T36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
Erythromycin (salts)
  »ophthalmic preparation
T36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
Erythromycin (salts)
  »topical NEC
T36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
IlotycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
Ilotycin
  »ophthalmic preparation
T36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
Ilotycin
  »topical NEC
T36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
JosamycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
KitasamycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
MidecamycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
MiokamycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
OleandomycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
PristinamycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
RokitamycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
RoxithromycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
SpiramycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
TAOT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
TriacetyloleandomycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
TroleandomycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6

Patient Education


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

What is a drug interaction?

A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as gingko and blood thinners
  • Drugs and medical conditions, such as aspirin and peptic ulcers

Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.

What are side effects?

Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.

What are drug allergies?

Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.

How can I stay safe when taking medicines?

When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.