2026 ICD-10-CM Diagnosis Code T36.3X2APoisoning by macrolides, intentional self-harm, initial encounter

ICD-10-CM CodesS00–T88T36-T50T36

ICD-10-CM T36.3X2A
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

T36.3X2A is a billable ICD-10-CM diagnosis code for poisoning by macrolides, intentional self-harm, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 917 through 918. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under External cause codes: intent of injury, self-harm; External cause codes: poisoning by drug; and Poisoning by drugs, initial encounter.

Code Identity

ICD-10-CM Code
T36.3X2A
Billable Status
Yes — Valid for Submission
Code Describes
Poisoning by macrolides, intentional self-harm, initial encounter
Short Description
Poisoning by macrolides, intentional self-harm, init encntr
Parent Code
Poisoning by macrolides, intentional self-harm

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT36Poisoning by, adverse effect of and underdosing of systemic antibiotics
This CodeT36.3X2APoisoning by macrolides, intentional self-harm, initial encounter

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Azithromycin overdose
  • Azithromycin poisoning
  • Clarithromycin overdose
  • Clarithromycin poisoning
  • Erythromycin overdose
  • Erythromycin poisoning
  • Intentional azithromycin overdose
  • Intentional azithromycin poisoning
  • Intentional clarithromycin overdose
  • Intentional clarithromycin poisoning
  • Intentional erythromycin overdose
  • Intentional erythromycin poisoning
  • Intentional oleandomycin poisoning
  • Intentional spiramycin poisoning
  • Macrolide antibacterial overdose
  • Poisoning by oleandomycin
  • Poisoning by spiramycin

Coding GuidelinesGuidance

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined). If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of systemic antibiotics (T36). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR EXT021
External cause codes: intent of injury, self-harm
Default principal diagnosis: inpatient No · outpatient No
CCSR EXT014
External cause codes: poisoning by drug
Default principal diagnosis: inpatient No · outpatient No
CCSR INJ022
Poisoning by drugs, initial encounter
Default principal diagnosis: inpatient No · outpatient No
CCSR MBD012
Suicidal ideation/attempt/intentional self-harm
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Azithromycin

    a semi-synthetic macrolide antibiotic structurally related to erythromycin. it has been used in the treatment of mycobacterium avium intracellulare infections, toxoplasmosis, and cryptosporidiosis.
  • Josamycin

    a macrolide antibiotic from streptomyces narbonensis. the drug has antimicrobial activity against a wide spectrum of pathogens.
  • Kitasamycin

    a macrolide antibiotic produced by streptomyces kitasatoensis. the drug has antimicrobial activity against a wide spectrum of pathogens.
  • Oleandomycin

    antibiotic macrolide produced by streptomyces antibioticus.
  • Pristinamycin

    an antibiotic mixture originally isolated from streptomyces pristinaspiralis. it is a mixture of compounds from streptogramin group a: pristinamycin iia and iib and from streptogramin group b: pristinamycin ia, pristinamycin ib, pristinamycin ic.
  • Streptogramin A

    a specific streptogramin group a antibiotic produced by streptomyces graminofaciens and other bacteria.
  • Streptogramin B

    a specific streptogramin group b antibiotic produced by streptomyces graminofaciens and other bacteria.
  • Roxithromycin

    semisynthetic derivative of erythromycin. it is concentrated by human phagocytes and is bioactive intracellularly. while the drug is active against a wide spectrum of pathogens, it is particularly effective in the treatment of respiratory and genital tract infections.
  • Spiramycin

    a macrolide antibiotic produced by streptomyces ambofaciens. the drug is effective against gram-positive aerobic pathogens, n. gonorrhoeae, and staphylococci. it is used to treat infections caused by bacteria and toxoplasma gondii.
  • Troleandomycin

    a macrolide antibiotic that is similar to erythromycin.

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
AzithromycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
Erythromycin (salts)T36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
Erythromycin (salts)::ophthalmic preparationT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
Erythromycin (salts)::topical NECT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
IlotycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
Ilotycin::ophthalmic preparationT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
Ilotycin::topical NECT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
JosamycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
KitasamycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
MidecamycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
MiokamycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
OleandomycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
PristinamycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
RokitamycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
RoxithromycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
SpiramycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
TAOT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
TriacetyloleandomycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6
TroleandomycinT36.3X1T36.3X2T36.3X3T36.3X4T36.3X5T36.3X6

Patient EducationClinical

Antibiotics

Antibiotics are medicines that fight bacterial infections in people and animals. They work by killing the bacteria or by making it hard for the bacteria to grow and multiply.

The full article covers:

  • What are antibiotics?
  • What do antibiotics treat?
  • Do antibiotics treat viral infections?
  • What are the side effects of antibiotics?
  • Why is it important to take antibiotics only when they're needed?
  • How do I use antibiotics correctly?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T36.3X2A to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
960.3 Pois-erythromyc/macrolid
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
E950.4 Poison-drug/medicin NEC
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About T36.3X2AOverview

Is T36.3X2A (Poisoning by macrolides, intentional self-harm) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report poisoning by macrolides, intentional self-harm, initial encounter on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What does the 7th character A in T36.3X2A mean?

The final character A marks the initial encounter: use it while the patient is receiving active treatment for poisoning by macrolides, intentional self-harm, such as an emergency visit or first evaluation.

What MS-DRG does T36.3X2A group to?

When poisoning by macrolides, intentional self-harm, initial encounter is the principal diagnosis on an inpatient stay, it groups to MS-DRG 917, 918, with relative weights from 0.8571 to 1.5684 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of T36.3X2A?

Under the General Equivalence Mappings, poisoning by macrolides, intentional self-harm, initial encounter converts to ICD-9-CM 960.3 (pois-erythromyc/macrolid) and E950.4 (poison-drug/medicin NEC). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.