ICD-10-CM Q87.88
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

Q87.88 is a billable ICD-10-CM diagnosis code for CTNNB1 syndrome. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The code is exempt from POA reporting.

Code Identity

ICD-10-CM Code
Q87.88
Billable Status
Yes — Valid for Submission
Code Describes
CTNNB1 syndrome
Short Description
CTNNB1 syndrome
Same as the full description in the CMS dataset.
Parent Code
Other specified congenital malformation syndromes, not elsewhere classified

Code Classification

ChapterQ00-Q99Congenital malformations, deformations and chromosomal abnormalities
SectionQ80-Q89Other congenital malformations
CategoryQ87Other specified congenital malformation syndromes affecting multiple systems
This CodeQ87.88CTNNB1 syndrome

Present on Admission (POA)Billing

Q87.88 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Use Additional Code

  • code, if applicable, for associated conditions such as:
  • cerebral palsy G80
  • congenital heart malformations Q20.0 Q24.9
  • developmental disorder of speech and language F80
  • exudative retinopathy H35.02
  • intellectual disability F70 F79
  • microcephaly Q02

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Syndrome
      • CTNNB1

Code History & ChangesHistory

New Code Q87.88 was added to the ICD-10-CM code set for FY 2026, effective October 1, 2025.

Replacement Q87.88 replaces the following previously assigned code(s):

  • Q87.89 - Oth congenital malformation syndromes, NEC
FY 2026AddedAdded to the ICD-10-CM code setEffective October 1, 2025.
FY 2026CurrentRevised in the current code setEffective October 1, 2025 through September 30, 2026.

Questions About Q87.88Overview

Is Q87.88 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report CTNNB1 syndrome on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Is Q87.88 exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for CTNNB1 syndrome on inpatient claims.