2026 ICD-10-CM Diagnosis Code Q75.3Macrocephaly

ICD-10-CM Codes›Q00-Q99›Q65-Q79›Q75

ICD-10-CM Q75.3
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

Q75.3 is a billable ICD-10-CM diagnosis code for macrocephaly. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 564 through 566. The code is exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Musculoskeletal congenital conditions.

Code Identity

ICD-10-CM Code
Q75.3
Billable Status
Yes — Valid for Submission
Code Describes
Macrocephaly
Short Description
Macrocephaly
Same as the full description in the CMS dataset.
Parent Code
Q75
Other congenital malformations of skull and face bones

Code Classification

ChapterQ00-Q99Congenital malformations, deformations and chromosomal abnormalities
SectionQ65-Q79Congenital malformations and deformations of the musculoskeletal system
CategoryQ75Other congenital malformations of skull and face bones
This CodeQ75.3Macrocephaly

Present on Admission (POA)Billing

Q75.3 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Agenesis of corpus callosum, macrocephaly, hypertelorism syndrome
  • Atkin Flaitz syndrome
  • Autosomal dominant intellectual disability, craniofacial dysmorphism, macrocephaly, hypotonia syndrome due to H1-4 mutation
  • Clark Baraitser syndrome
  • Colobomatous microphthalmia
  • COMMAD syndrome
  • Complete deafness
  • Congenital abnormal shape of rib
  • Congenital deafness
  • Congenital dysplasia of nail unit
  • Congenital macrocephaly
  • Congenital pectus excavatum
  • Cutis laxa, autosomal recessive
  • Dandy-Walker syndrome
  • Deformity of sternum
  • Disorder of ornithine metabolism
  • Facial dysmorphism, macrocephaly, myopia, Dandy-Walker malformation syndrome
  • Fryns macrocephaly
  • Genetic syndromic childhood obesity
  • Global developmental delay, alopecia, macrocephaly, facial dysmorphism, structural brain anomalies syndrome
  • Intellectual disability, coarse face, macrocephaly, cerebellar hypotrophy syndrome
  • Intellectual disability, macrocephaly, hypotonia, behavioral abnormalities syndrome
  • Intellectual disability, seizures, macrocephaly, obesity syndrome
  • Left ventricular myocardial noncompaction cardiomyopathy
  • Macrocephaly
  • Macrocephaly and developmental delay syndrome
  • Macrocephaly, intellectual disability, autism syndrome
  • Macrocephaly, intellectual disability, left ventricular non compaction syndrome
  • Macrocephaly, intellectual disability, neurodevelopmental disorder, small thorax syndrome
  • Macrocephaly, short stature, paraplegia syndrome
  • Macroencephaly
  • MACS syndrome
  • Megalencephaly capillary malformation
  • MOMO syndrome
  • Overgrowth, macrocephaly, facial dysmorphism syndrome
  • Pectus deformity of chest
  • Pectus excavatum
  • Pectus excavatum, macrocephaly, dysplastic nails syndrome
  • Relative macrocephaly
  • Seizures, scoliosis, macrocephaly syndrome
  • Ventricular myocardial noncompaction cardiomyopathy
  • X-linked intellectual disability, macrocephaly, macroorchidism syndrome
  • X-linked recessive intellectual disability and macrocephaly with ciliary dysfunction syndrome

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Macrocephalia, macrocephaly
    • Megalocephalus, megalocephaly NEC

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR MAL008
Musculoskeletal congenital conditions
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Craniofacial Abnormalities

Craniofacial is a medical term that relates to the bones of the skull and face. Craniofacial abnormalities are birth defects of the face or head. Some, like cleft lip and palate, are among the most common of all birth defects. Others are very rare. Most of them affect how a person's face or head looks.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert Q75.3 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
756.0 Anomal skull/face bones
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About Q75.3Overview

Is Q75.3 (Other congenital malformations of skull and face bones) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report macrocephaly on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does Q75.3 group to?

When macrocephaly is the principal diagnosis on an inpatient stay, it groups to MS-DRG 564, 565, 566, with relative weights from 0.7493 to 1.5436 depending on complications. Higher weights mean higher Medicare reimbursement.

Is Q75.3 exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for macrocephaly on inpatient claims.

What is the ICD-9 equivalent of Q75.3?

Under the General Equivalence Mappings, macrocephaly converts to ICD-9-CM 756.0 (anomal skull/face bones). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.