2027 ICD-10-CM Diagnosis Code M62.81Muscle weakness (generalized)

ICD-10-CM Codes›M00–M99›M60-M63›M62

ICD-10-CM M62.81
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

M62.81 is a billable ICD-10-CM diagnosis code for muscle weakness (generalized). It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 555 through 556. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Muscle disorders.

Code Identity

ICD-10-CM Code
M62.81
Billable Status
Yes — Valid for Submission
Code Describes
Muscle weakness (generalized)
Short Description
Muscle weakness (generalized)
Same as the full description in the CMS dataset.
Parent Code
Other specified disorders of muscle

Code Classification

ChapterM00–M99Diseases of the musculoskeletal system and connective tissue
SectionM60-M63Disorders of muscles
CategoryM62Other disorders of muscle
This CodeM62.81Muscle weakness (generalized)

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Abnormal gait due to muscle weakness
  • Absence of power in skeletal muscle
  • Asthenia
  • Bilateral weakness of upper limbs
  • Bone age finding
  • Calf muscle weakness
  • Delayed bone age
  • Diffuse atrophy of cerebrum
  • Distal muscle weakness
  • Dropped head syndrome
  • Early-onset progressive diffuse brain atrophy, microcephaly, muscle weakness, optic atrophy syndrome
  • Fatigable weakness of chewing muscle
  • Fatigable weakness of muscle
  • Fatigable weakness of muscle of forearm
  • Fatigable weakness of muscle of hip and/or thigh
  • Fatigable weakness of muscle of lower leg
  • Fatigable weakness of muscle of neck
  • Fatigable weakness of muscle of upper arm
  • Fatigable weakness of respiratory muscle
  • Fatigable weakness of speech muscle
  • Fatigable weakness of swallowing muscle
  • Finding of movement of hand
  • Generalized hypotonia due to neuromuscular junction defect
  • Generalized muscle weakness
  • Global brain atrophy
  • Grade of muscle power - finding
  • Hand muscle weakness
  • Increased fatigable weakness of muscle
  • Insufficient power to move joint
  • Intellectual disability, muscle weakness, short stature, facial dysmorphism syndrome
  • Late onset weakness of distal muscle
  • Late onset weakness of proximal muscle
  • Mitochondrially encoded ATP synthase membrane subunit 6-related mitochondrial disease
  • Muscle weakness
  • Muscle weakness of limb
  • Muscle weakness of upper arm
  • Muscle weakness of upper limb
  • NARP syndrome
  • Neurological muscle weakness
  • Paresis of left lower limb
  • Paresis of right lower limb
  • Peroneal muscle weakness
  • Progressive weakness of distal muscle
  • Progressive weakness of muscle
  • Progressive weakness of proximal muscle
  • Proximal muscle weakness
  • Pyramidal type muscle weakness
  • Quadriceps weakness
  • Second cranial nerve finding
  • Severe hypotonia of muscle
  • Skeletal muscle power problem
  • Truncal muscle weakness
  • Weak mouth closure
  • Weak teeth clenching
  • Weakness of anterior tibialis muscle
  • Weakness of axial muscle
  • Weakness of back
  • Weakness of bilateral lower limb
  • Weakness of distal arms and legs
  • Weakness of extensor muscle of finger
  • Weakness of extremities as sequela of stroke
  • Weakness of first dorsal interosseous muscle of hand
  • Weakness of flexor muscle of finger
  • Weakness of flexor muscle of hip joint
  • Weakness of hand
  • Weakness of intercostal muscle
  • Weakness of intrinsic muscle of hand
  • Weakness of jaw muscles
  • Weakness of left lower limb
  • Weakness of left upper limb
  • Weakness of muscle of ankle region
  • Weakness of muscle of forearm
  • Weakness of muscle of lower leg
  • Weakness of muscle of lower limb
  • Weakness of muscle of respiration
  • Weakness of neck flexor muscle
  • Weakness of right lower limb
  • Weakness of right upper limb
  • Weakness of scapuloperoneal muscle
  • Weakness of sternomastoid
  • Weakness of thenar muscle
  • Weakness of triceps brachii muscle
  • Weakness present

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to M62.81: its own notes plus those printed at M62.8, M62, block M60-M63, and Chapter 13. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

On M62.81 itself
  • muscle weakness in sarcopenia (M62.84)
From M62 Other disorders of muscle applies to 131 codes
From Block M60-M63 Disorders of muscles applies to 420 codes
  • dermatopolymyositis (M33.-)
  • myopathy in amyloidosis (E85.-)
  • myopathy in polyarteritis nodosa (M30.0)
  • myopathy in rheumatoid arthritis (M05.32)
  • myopathy in scleroderma (M34.-)
  • myopathy in Sjögren's syndrome (M35.03)
  • myopathy in systemic lupus erythematosus (M32.-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From M62.8 Other specified disorders of muscle applies to 8 codes
  • nontraumatic hematoma of muscle (M79.81)
From M62 Other disorders of muscle applies to 131 codes
  • nontraumatic hematoma of muscle (M79.81)
From Block M60-M63 Disorders of muscles applies to 420 codes
  • muscular dystrophies and myopathies (G71-G72)
From Chapter 13 (M00-M99) Diseases of the musculoskeletal system and connective tissue applies to 6,687 codes
  • arthropathic psoriasis (L40.5-)
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • compartment syndrome (traumatic) (T79.A-)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Notes

General instructions on how these codes are used.

From Chapter 13 (M00-M99) Diseases of the musculoskeletal system and connective tissue applies to 6,687 codes
  • Use an external cause code following the code for the musculoskeletal condition, if applicable, to identify the cause of the musculoskeletal condition

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name M62.81, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming M62.81: they are not reported together with it, unless the two conditions are unrelated.

  • R53.1 Weakness
    muscle weakness (generalized) (M62.81)

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR MUS026
Muscle disorders
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Muscle Weakness

    a vague complaint of debility, fatigue, or exhaustion attributable to weakness of various muscles. the weakness can be characterized as subacute or chronic, often progressive, and is a manifestation of many muscle and neuromuscular diseases. (from wyngaarden et al., cecil textbook of medicine, 19th ed, p2251)

Patient EducationClinical

Muscle Disorders

Your muscles help you move and help your body work. Different types of muscles have different jobs. There are many problems that can affect muscles. Muscle disorders can cause weakness, pain or even paralysis.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert M62.81 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
728.87 Muscle weakness-general
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About M62.81Overview

What is the ICD-10 code for muscle weakness (generalized)?

The ICD-10-CM code for muscle weakness (generalized) is M62.81 (sometimes written as M6281). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is M62.81 (Other specified disorders of muscle) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report muscle weakness (generalized) on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does M62.81 group to?

When muscle weakness (generalized) is the principal diagnosis on an inpatient stay, it groups to MS-DRG 555, 556, with relative weights from 0.8210 to 1.2908 depending on complications. Higher weights mean higher Medicare reimbursement.

Can M62.81 be reported with M62.84?

Not as a rule. The Excludes1 note on M62.81 lists "muscle weakness in sarcopenia (M62.84)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What is the ICD-9 equivalent of M62.81?

Under the General Equivalence Mappings, muscle weakness (generalized) converts to ICD-9-CM 728.87 (muscle weakness-general). The mapping is a direct match.