2026 ICD-10-CM Diagnosis Code L53.0Toxic erythema

ICD-10-CM CodesL00–L99L49-L54L53

ICD-10-CM L53.0
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

L53.0 is a billable ICD-10-CM diagnosis code for toxic erythema. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 595 through 596. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Drug induced or toxic related condition and Other specified inflammatory condition of skin.

Code Identity

ICD-10-CM Code
L53.0
Billable Status
Yes — Valid for Submission
Code Describes
Toxic erythema
Short Description
Toxic erythema
Same as the full description in the CMS dataset.
Parent Code
Other erythematous conditions

Code Classification

ChapterL00–L99Diseases of the skin and subcutaneous tissue
SectionL49-L54Urticaria and erythema
CategoryL53Other erythematous conditions
This CodeL53.0Toxic erythema

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Acral erythema due to cytotoxic therapy
  • Annular erythema
  • Annular erythema caused by drug
  • Contact dermatitis caused by hydrocarbon
  • Contact dermatitis caused by ketone
  • Danthron erythema
  • Dermatosis due to cytotoxic therapy
  • Diffuse inflammatory erythema
  • Drug exanthem
  • Exanthematous disorder
  • Palmar erythema
  • Toxic erythema caused by drug
  • Toxic urticated erythema
  • Toxic urticated erythema caused by drug

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Code First

  • poisoning due to drug or toxin, if applicable T36 T65

Use Additional Code

  • code for adverse effect, if applicable, to identify drug T36 T50

Type 1 Excludes

  • neonatal erythema toxicum P83.1

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Eruption
      • skin (nonspecific)
        • toxic NEC
    • Erythema, erythematous(infectional) (inflammation)
      • due to
        • chemical NEC
    • Erythema, erythematous(infectional) (inflammation)
      • toxic, toxicum NEC

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ030
Drug induced or toxic related condition
Default principal diagnosis: inpatient No · outpatient No
CCSR SKN002
Other specified inflammatory condition of skin
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Skin Conditions

Your skin is your body's largest organ. It covers the entire outside of your body. There are many ways that your skin protects your body and helps keep you healthy. For example, it:

The full article covers:

  • What does your skin do?
  • What problems and conditions can affect your skin?
  • How can I keep my skin healthy?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert L53.0 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
695.0 Toxic erythema
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About L53.0Overview

Is L53.0 (Other erythematous conditions) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report toxic erythema on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does L53.0 group to?

When toxic erythema is the principal diagnosis on an inpatient stay, it groups to MS-DRG 595, 596, with relative weights from 1.0825 to 2.1207 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of L53.0?

Under the General Equivalence Mappings, toxic erythema converts to ICD-9-CM 695.0 (toxic erythema). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.