2027 ICD-10-CM Diagnosis Code L25.1Unspecified contact dermatitis due to drugs in contact with skin

ICD-10-CM Codes›L00–L99›L20-L30›L25

ICD-10-CM L25.1
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

L25.1 is a billable ICD-10-CM diagnosis code for unspecified contact dermatitis due to drugs in contact with skin. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 606 through 607. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Contact dermatitis and Drug induced or toxic related condition.

Code Identity

ICD-10-CM Code
L25.1
Billable Status
Yes — Valid for Submission
Code Describes
Unspecified contact dermatitis due to drugs in contact with skin
Short Description
Unsp contact dermatitis due to drugs in contact with skin
Parent Code
Unspecified contact dermatitis

Code Classification

ChapterL00–L99Diseases of the skin and subcutaneous tissue
SectionL20-L30Dermatitis and eczema
CategoryL25Unspecified contact dermatitis
This CodeL25.1Unspecified contact dermatitis due to drugs in contact with skin

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Contact dermatitis caused by hydrocarbon
  • Contact dermatitis caused by iodine
  • Contact dermatitis caused by keratolytic
  • Contact dermatitis caused by medication
  • Contact dermatitis caused by neomycin
  • Contact dermatitis caused by pediculicide
  • Contact dermatitis caused by phenol
  • Contact dermatitis caused by scabicide
  • Halogen eruption
  • Iododerma
  • Lanolin contact dermatitis
  • Oil contact dermatitis

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to L25.1: its own notes plus those printed at L25, block L20-L30, and Chapter 12. A note printed at a category, block or chapter applies to every code under it.

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From L25 Unspecified contact dermatitis applies to 8 codes
  • allergic contact dermatitis (L23.-)
  • allergy NOS (T78.40)
  • dermatitis NOS (L30.9)
  • irritant contact dermatitis (L24.-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

On L25.1 itself
  • dermatitis due to ingested drugs and medicaments (L27.0-L27.1)
From L25 Unspecified contact dermatitis applies to 8 codes
  • dermatitis due to ingested substances (L27.-)
  • dermatitis of eyelid (H01.1-)
  • eczema of external ear (H60.5-)
  • perioral dermatitis (L71.0)
  • radiation-related disorders of the skin and subcutaneous tissue (L55-L59)
From Block L20-L30 Dermatitis and eczema applies to 74 codes
  • chronic (childhood) granulomatous disease (D71-)
  • dermatitis gangrenosa (L08.0)
  • dermatitis herpetiformis (L13.0)
  • dry skin dermatitis (L85.3)
  • factitial dermatitis (L98.1)
  • perioral dermatitis (L71.0)
  • radiation-related disorders of the skin and subcutaneous tissue (L55-L59)
  • stasis dermatitis (I87.2)
From Chapter 12 (L00-L99) Diseases of the skin and subcutaneous tissue applies to 1,001 codes
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • lipomelanotic reticulosis (I89.8)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
  • systemic connective tissue disorders (M30-M36)
  • viral warts (B07.-)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Notes

General instructions on how these codes are used.

From Block L20-L30 Dermatitis and eczema applies to 74 codes
  • In this block the terms dermatitis and eczema are used synonymously and interchangeably.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name L25.1, its category, or a range that includes it.

Excludes1 2

These codes carry an Excludes1 note naming L25.1: they are not reported together with it, unless the two conditions are unrelated.

  • L53 Other erythematous conditions
    erythema due to external agents in contact with skin (L23-L25) names L23-L25, which includes this code
  • T78.4 Other and unspecified allergy
    dermatitis (L23-L25, L27.-) names L23-L25, which includes this code

Excludes2 4

These codes carry an Excludes2 note naming L25.1: its condition is not part of those codes, and both may be reported when the patient has both.

  • T81 Complications of procedures, not elsewhere classified
    dermatitis due to drugs and medicaments (L23.3, L24.4, L25.1, L27.0-L27.1)
  • T88 Other complications of surgical and medical care, not elsewhere classified
    dermatitis due to drugs and medicaments (L23.3, L24.4, L25.1, L27.0-L27.1)
  • L27 Dermatitis due to substances taken internally
    contact dermatitis (L23-L25) names L23-L25, which includes this code
  • L30 Other and unspecified dermatitis
    contact dermatitis (L23-L25) names L23-L25, which includes this code

Code First 2

These codes say to code first a condition named in the note, and L25.1 is one of the conditions named.

  • F54 Psychological and behavioral factors associated with disorders or diseases classified elsewhere
    dermatitis (L23-L25) names L23-L25, which includes this code
  • Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
    contact dermatitis (L23-L25) names L23-L25, which includes this code

Index to Diseases and InjuriesGuidance

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR SKN005
Contact dermatitis
Default principal diagnosis: inpatient No · outpatient No
CCSR INJ030
Drug induced or toxic related condition
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Rashes

A rash is an area of irritated or swollen skin. Many rashes are itchy, red, painful, and irritated. Some rashes can also lead to blisters or patches of raw skin. Rashes are a symptom of many different medical problems. Other causes include irritating substances and allergies. Certain genes can make people more likely to get rashes.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert L25.1 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
692.3 Topical med dermatitis
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About L25.1Overview

What is the ICD-10 code for unspecified contact dermatitis due to drugs in contact with skin?

The ICD-10-CM code for unspecified contact dermatitis due to drugs in contact with skin is L25.1 (sometimes written as L251). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is L25.1 (Unspecified contact dermatitis) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report unspecified contact dermatitis due to drugs in contact with skin on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does L25.1 group to?

When unspecified contact dermatitis due to drugs in contact with skin is the principal diagnosis on an inpatient stay, it groups to MS-DRG 607, 606, with relative weights from 0.8772 to 1.5721 depending on complications. Higher weights mean higher Medicare reimbursement.

Can L25.1 be reported with a code from L23?

Not as a rule. The Excludes1 note at L25, which applies to L25.1, lists "allergic contact dermatitis (L23.-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

Does L25.1 need an additional code?

When the condition applies, yes. The Use Additional Code note reads: code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5). The additional code is reported after L25.1.