2026 ICD-10-CM Diagnosis Code L25.1Unspecified contact dermatitis due to drugs in contact with skin

ICD-10-CM CodesL00–L99L20-L30L25

ICD-10-CM L25.1
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

L25.1 is a billable ICD-10-CM diagnosis code for unspecified contact dermatitis due to drugs in contact with skin. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 606 through 607. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Contact dermatitis and Drug induced or toxic related condition.

Code Identity

ICD-10-CM Code
L25.1
Billable Status
Yes — Valid for Submission
Code Describes
Unspecified contact dermatitis due to drugs in contact with skin
Short Description
Unsp contact dermatitis due to drugs in contact with skin
Parent Code
Unspecified contact dermatitis

Code Classification

ChapterL00–L99Diseases of the skin and subcutaneous tissue
SectionL20-L30Dermatitis and eczema
CategoryL25Unspecified contact dermatitis
This CodeL25.1Unspecified contact dermatitis due to drugs in contact with skin

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Contact dermatitis caused by hydrocarbon
  • Contact dermatitis caused by iodine
  • Contact dermatitis caused by keratolytic
  • Contact dermatitis caused by medication
  • Contact dermatitis caused by neomycin
  • Contact dermatitis caused by pediculicide
  • Contact dermatitis caused by phenol
  • Contact dermatitis caused by scabicide
  • Halogen eruption
  • Iododerma
  • Lanolin contact dermatitis
  • Oil contact dermatitis

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Use Additional Code

  • code for adverse effect, if applicable, to identify drug T36 T50

Type 2 Excludes

  • dermatitis due to ingested drugs and medicaments L27.0 L27.1

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Dermatitis(eczematous)
      • contact (occupational)
        • due to
          • drugs in contact with skin
    • Dermatitis(eczematous)
      • due to
        • drugs and medicaments (generalized) (internal use)
          • in contact with skin
    • Rash(toxic)
      • drug (internal use)
        • contact

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR SKN005
Contact dermatitis
Default principal diagnosis: inpatient No · outpatient No
CCSR INJ030
Drug induced or toxic related condition
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Allergic Contact Dermatitis

    an inflammatory skin condition caused by an immune response to direct contact between the skin and an allergen. it consists of a delayed type of allergic reaction at the affected site with resulting red, swollen, and blistered skin that may itch or leak.
  • Contact Dermatitis

    an inflammatory skin condition caused by direct contact between the skin and either an irritating substance or an allergen.
  • Irritant Contact Dermatitis

    an inflammatory skin condition caused by direct contact between the skin and an irritating substance. it is typically manifested by erythema, mild edema, and scaling at the affected site.
  • Primula Dermatitis|Contact dermatitis due to primrose

    allergic contact dermatitis secondary to exposure to organic compounds found in primula (primrose) species.

Patient EducationClinical

Rashes

A rash is an area of irritated or swollen skin. Many rashes are itchy, red, painful, and irritated. Some rashes can also lead to blisters or patches of raw skin. Rashes are a symptom of many different medical problems. Other causes include irritating substances and allergies. Certain genes can make people more likely to get rashes.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert L25.1 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
692.3 Topical med dermatitis
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About L25.1Overview

Is L25.1 (Unspecified contact dermatitis) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report unspecified contact dermatitis due to drugs in contact with skin on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does L25.1 group to?

When unspecified contact dermatitis due to drugs in contact with skin is the principal diagnosis on an inpatient stay, it groups to MS-DRG 606, 607, with relative weights from 0.9064 to 1.5132 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of L25.1?

Under the General Equivalence Mappings, unspecified contact dermatitis due to drugs in contact with skin converts to ICD-9-CM 692.3 (topical med dermatitis). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.