Dermatitis due to substances taken internally (L27) ICD-10-CM
The L27 code range covers dermatitis due to substances taken internally with 6 ICD-10-CM diagnosis codes. 5 of them are billable and valid for claim submission in fiscal year 2027, and the category headers group them but cannot themselves be billed.
Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
- allergy NOS T78.40
Type 2 Excludes
A type 2 excludes note represents "Not included here". An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.
Codes in the L27 Range 6 codes · 5 billable
- L27 Dermatitis due to substances taken internallyNon-billable
- L27.0 Generalized skin eruption due to drugs and medicaments taken internally
- L27.1 Localized skin eruption due to drugs and medicaments taken internally
- L27.2 Dermatitis due to ingested food
- L27.8 Dermatitis due to other substances taken internally
- L27.9 Dermatitis due to unspecified substance taken internally
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the L27 range.
Dermatitis due to Unspecified Substance Taken Internally
Dermatitis caused by an allergic reaction to an unspecified ingested substance.
Hand-Foot Syndrome
Chemotherapy-induced dermal side effects that are associated with the use of various CYTOSTATIC AGENTS. Symptoms range from mild ERYTHEMA and/or PARESTHESIA to severe ulcerative dermatitis with debilitating pain involving typically palmoplantar and intertriginous areas. These cutaneous manifestations are sometimes accompanied by nail anomalies.
About the L27 Code Range
Dermatitis and skin eruptions in L27 result from substances taken internally.
Drug-related skin eruptions are separated into generalized eruptions (L27.0) and localized eruptions (L27.1). The remaining subdivisions identify dermatitis due to ingested food (L27.2), other substances taken internally (L27.8), or an unspecified substance taken internally (L27.9).
Questions About This Page
How many billable codes are in the L27 range?
Of the 6 codes in this range, 5 are billable and valid for claim submission from October 1, 2026 through September 30, 2027. Category header codes group them but cannot be reported on claims.
What does the L27 range classify?
The range classifies dermatitis due to substances taken internally. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2027 ICD-10-CM Tabular List and order file, effective October 1, 2026 through September 30, 2027.
