2026 ICD-10-CM Diagnosis Code K76.82Hepatic encephalopathy

ICD-10-CM Codes›K00–K95›K70-K77›K76

ICD-10-CM K76.82
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

K76.82 is a billable ICD-10-CM diagnosis code for hepatic encephalopathy. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 441 through 443. Coders also document this condition as delirium due to hepatic encephalopathy. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other nervous system disorders (neither hereditary nor degenerative) and Other specified and unspecified liver disease.

Code Identity

ICD-10-CM Code
K76.82
Billable Status
Yes — Valid for Submission
Code Describes
Hepatic encephalopathy
Short Description
Hepatic encephalopathy
Same as the full description in the CMS dataset.
Parent Code
K76.8
Other specified diseases of liver

Code Classification

ChapterK00–K95Diseases of the digestive system
SectionK70-K77Diseases of liver
CategoryK76Other diseases of liver
This CodeK76.82Hepatic encephalopathy

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Delirium due to hepatic encephalopathy
  • Hepatic coma
  • Hepatic coma due to hepatitis
  • Hepatic encephalopathy
  • Hepatic encephalopathy in fulminant hepatic failure
  • Hepatoencephalopathy due to combined oxidative phosphorylation defect type 1
  • Portal systemic encephalopathy

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Hepatic encephalopathy, NOS
  • Hepatic encephalopathy without coma
  • Hepatocerebral intoxication
  • Portal-systemic encephalopathy

Code Also

  • underlying liver disease, such as:
  • acute and subacute hepatic failure without coma K72.00
  • alcoholic hepatic failure without coma K70.40
  • chronic hepatic failure without coma K72.10
  • hepatic failure with toxic liver disease without coma K71.10
  • hepatic failure without coma K72.90
  • icterus of newborn P55 P59
  • postprocedural hepatic failure K91.82
  • viral hepatitis without hepatic coma B15.9 B16.1 B16.9 B17.10 B19.10 B19.20 B19.9

Type 1 Excludes

  • acute and subacute hepatic failure with coma K72.01
  • alcoholic hepatic failure with coma K70.41
  • chronic hepatic failure with coma K72.11
  • hepatic failure with coma K72.91

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Encephalopathy(acute)
      • hepatic (without coma)
    • Encephalopathy(acute)
      • portal-systemic
    • Intoxication
      • hepatocerebral

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NVS020
Other nervous system disorders (neither hereditary nor degenerative)
Default principal diagnosis: inpatient No · outpatient No
CCSR DIG019
Other specified and unspecified liver disease
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Hepatic Encephalopathy

    a syndrome characterized by central nervous system dysfunction in association with liver failure, including portal-systemic shunts. clinical features include lethargy and confusion (frequently progressing to coma); asterixis; nystagmus, pathologic; brisk oculovestibular reflexes; decorticate and decerebrate posturing; muscle spasticity; and bilateral extensor plantar reflexes (see reflex, babinski). electroencephalography may demonstrate triphasic waves. (from adams et al., principles of neurology, 6th ed, pp1117-20; plum & posner, diagnosis of stupor and coma, 3rd ed, p222-5)

  • CDISC Clinical Classification West Haven Criteria Test Code Terminology|CC-West Haven Criteria TESTCD|WHEG01TC|West Haven Hepatic Encephalopathy Grade Clinical Classification Test Code

    test codes of clinical classification questions associated with the west haven hepatic encephalopathy grade (west haven criteria) for the clinical data interchange standards consortium (cdisc) study data tabulation model (sdtm).

  • CDISC Clinical Classification West Haven Criteria Test Name Terminology|CC-West Haven Criteria TEST|WHEG01TN|West Haven Hepatic Encephalopathy Grade Clinical Classification Test Name

    test names of clinical classification questions associated with the west haven hepatic encephalopathy grade (west haven criteria) for the clinical data interchange standards consortium (cdisc) study data tabulation model (sdtm).

  • CDISC SDTM West Haven Hepatic Encephalopathy Grade Terminology|HEPENCGR|SDTM-HEPENCGR|West Haven Hepatic Encephalopathy Grade

    terminology associated with the west haven hepatic encephalopathy grade codelist of the clinical data interchange standards consortium (cdisc) study data tabulation model (sdtm).

  • Hepatic Encephalopathy

    a constellation of signs and symptoms characterized by changes in personality, consciousness, and reflexes, resulting from neuropsychiatric abnormalities secondary to liver failure without evidence of other brain disease.

  • West Haven Criteria - West Haven Hepatic Encephalopathy Grade|WHEG01-WH Hepatic Encephalopathy Grade|WHEG01-WH Hepatic Encephalopathy Grade|WHEG0101

    west haven hepatic encephalopathy grade (west haven criteria) grade.

  • West Haven Hepatic Encephalopathy Grade 0|GRADE 0

    minimal - symptoms or pathological characteristics include minimal hepatic encephalopathy, lack of detectable changes in personality or behavior, minimal changes in memory, concentration and intellectual function, and absence of coordination asterixis. (adapted from: hepatic encephalopathy. david c wolf. http://emedicine.medscape.com/article/186101-overview)

  • West Haven Hepatic Encephalopathy Grade 1|GRADE 1

    mild - symptoms or pathological characteristics include trivial lack of awareness, shortened attention span, impaired ability to perform addition or subtraction, hypersomnia, insomnia, or inversion of sleep pattern, euphoria, depression or irritability, mild confusion, slowing of ability to perform mental tasks. (adapted from: hepatic encephalopathy. david c wolf. http://emedicine.medscape.com/article/186101-overview.)

  • West Haven Hepatic Encephalopathy Grade 2|GRADE 2

    moderate - symptoms or pathological characteristics include lethargy or apathy, disorientation, inappropriate behavior, slurred speech, obvious asterixis, drowsiness, lethargy, gross deficits in ability to perform mental tasks, obvious personality changes, inappropriate behavior, and intermittent disorientation, unsurely regarding time. (adapted from: hepatic encephalopathy. david c wolf. http://emedicine.medscape.com/article/186101-overview.)

  • West Haven Hepatic Encephalopathy Grade 3|GRADE 3

    severe - symptoms or pathological characteristics include somnolence with some arousability, inability to perform mental tasks, disorientation about time and place, marked confusion, amnesia, occasional fits of rage, present but incomprehensible speech. (adapted from: hepatic encephalopathy. david c wolf. http://emedicine.medscape.com/article/186101-overview.)

  • West Haven Hepatic Encephalopathy Grade 4|GRADE 4

    coma - symptoms or pathological characteristics include coma with or without response to painful stimuli. (adapted from: hepatic encephalopathy. david c wolf. http://emedicine.medscape.com/article/186101-overview.)

  • West Haven Hepatic Encephalopathy Grade Clinical Classification|WEST HAVEN HEPATIC ENCEPHALOPATHY GRADE|WHEG01|West Haven Criteria

    a standardized rating scale developed by blei and cordoba in 2001, which is a classification system used to describe the severity of hepatic encephalopathy based on the level of mental status and intellectual function. this instrument has 4 grades.

Code History & ChangesHistory

Replacement K76.82 replaces the following previously assigned code(s):

  • K72.90 - Hepatic failure, unspecified without coma
  • K72.91 - Hepatic failure, unspecified with coma
FY 2023AddedAdded to the ICD-10-CM code setEffective October 1, 2022.
FY 2024–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About K76.82Overview

Is K76.82 (Other specified diseases of liver) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report hepatic encephalopathy on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does K76.82 group to?

When hepatic encephalopathy is the principal diagnosis on an inpatient stay, it groups to MS-DRG 441, 442, 443, with relative weights from 0.6997 to 1.7947 depending on complications. Higher weights mean higher Medicare reimbursement.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.