2027 ICD-10-CM Diagnosis Code K76.82Hepatic encephalopathy
ICD-10-CM Codes›K00–K95›K70-K77›K76
- Billable — Valid for Submission
- Risk Adjusts — HCC 63
- Chronic Condition
K76.82 is a billable ICD-10-CM diagnosis code for hepatic encephalopathy. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 441 through 443, 791, 793. Coders also document this condition as chronic hepatic encephalopathy. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other nervous system disorders (neither hereditary nor degenerative) and Other specified and unspecified liver disease.
For Medicare Advantage risk adjustment, K76.82 maps to CMS-HCC Category 63 (Chronic Liver Failure/End-Stage Liver Disorders) under the V28 model, adding a risk factor of about 0.962 for a community, non-dual, aged beneficiary in payment year 2027.
Code Identity
Code Classification
Medicare Risk Adjustment (HCC)Billing
K76.82 maps to a payment category in the CMS-HCC model used to risk-adjust Medicare Advantage payments. Weights are the published community factors for payment year 2027.
Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Chronic hepatic encephalopathy
- Delirium due to hepatic encephalopathy
- Hepatic coma
- Hepatic coma due to hepatitis
- Hepatic encephalopathy
- Hepatic encephalopathy in fulminant hepatic failure
- Hepatoencephalopathy due to combined oxidative phosphorylation defect type 1
- Portal systemic encephalopathy
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to K76.82: its own notes plus those printed at K76, block K70-K77, and Chapter 11. A note printed at a category, block or chapter applies to every code under it.
Applicable To
Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.
- Hepatic encephalopathy, NOS
- Hepatic encephalopathy without coma
- Hepatocerebral intoxication
- Portal-systemic encephalopathy
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
- jaundice NOS (R17)
Excludes2
Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.
- certain conditions originating in the perinatal period (P04-P96)
- certain infectious and parasitic diseases (A00-B99)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Code Also
A second code may be needed to fully describe the condition; the note gives no sequencing direction.
- underlying liver disease, such as:
- acute and subacute hepatic failure without coma (K72.00)
- alcoholic hepatic failure without coma (K70.40)
- chronic hepatic failure without coma (K72.10)
- hepatic failure with toxic liver disease without coma (K71.10)
- hepatic failure without coma (K72.90)
- icterus of newborn (P55-P59)
- postprocedural hepatic failure (K91.82)
- viral hepatitis without hepatic coma (B15.9, B16.1, B16.9, B17.10, B19.10, B19.20, B19.9)
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
hepatic (without coma) K76.82
portal-systemic K76.82
hepatocerebral K76.82
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Hepatic Encephalopathy
a syndrome characterized by central nervous system dysfunction in association with liver failure, including portal-systemic shunts. clinical features include lethargy and confusion (frequently progressing to coma); asterixis; nystagmus, pathologic; brisk oculovestibular reflexes; decorticate and decerebrate posturing; muscle spasticity; and bilateral extensor plantar reflexes (see reflex, babinski). electroencephalography may demonstrate triphasic waves. (from adams et al., principles of neurology, 6th ed, pp1117-20; plum & posner, diagnosis of stupor and coma, 3rd ed, p222-5)
Patient EducationClinical
Liver Diseases
Your liver is the largest organ inside your body. It helps your body digest food, store energy, and remove poisons.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Code History & ChangesHistory
Replacement K76.82 replaces the following previously assigned code(s):
- K72.90 - Hepatic failure, unspecified without coma
- K72.91 - Hepatic failure, unspecified with coma
Questions About K76.82Overview
What is the ICD-10 code for hepatic encephalopathy?
The ICD-10-CM code for hepatic encephalopathy is K76.82 (sometimes written as K7682). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is K76.82 (Other specified diseases of liver) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report hepatic encephalopathy on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does K76.82 group to?
When hepatic encephalopathy is the principal diagnosis on an inpatient stay, it groups to MS-DRG 793, 791, 442, 441, 443, with relative weights from 0.6890 to 4.2192 depending on complications. Higher weights mean higher Medicare reimbursement.
Can K76.82 be reported with K72.01?
Not as a rule. The Excludes1 note on K76.82 lists "acute and subacute hepatic failure with coma (K72.01)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
What HCC is K76.82?
K76.82 (hepatic encephalopathy) maps to CMS-HCC Category 63 (Chronic Liver Failure/End-Stage Liver Disorders), commonly written as HCC 63, in the CMS-HCC V28 model used for Medicare Advantage risk adjustment in payment year 2027. It mapped to HCC 27 under the retired V24 model. It also maps in the PACE (CMS-HCC V22), ESRD (V21), and ESRD (V24) models. It does not map to any RxHCC in the Part D prescription drug model.
Does K76.82 risk-adjust for Medicare Advantage payment?
Yes. When documented and reported on a Medicare Advantage encounter, K76.82 adds a risk adjustment factor of about 0.962 to the beneficiary's RAF score for a community, non-dual, aged enrollee (published V28 weights range from 0.861 to 1.209 depending on the payment segment). A more severe related category (HCC 62) supersedes it when both are reported. See the full factor table on the HCC 63 category page.
