Fibrosis and cirrhosis of liver (K74)

• ICD-10 Index

  • Diseases of the digestive system (K00–K93)

    • Diseases of liver (K70-K77)

      • Fibrosis and cirrhosis of liver (K74)

        • K74 - Fibrosis and cirrhosis of liver NON-BILLABLE CODE
        • K74.0 - Hepatic fibrosis NON-BILLABLE CODE
        • K74.00 - Hepatic fibrosis, unspecified BILLABLE CODE
        • K74.01 - Hepatic fibrosis, early fibrosis BILLABLE CODE
        • K74.02 - Hepatic fibrosis, advanced fibrosis BILLABLE CODE
        • K74.1 - Hepatic sclerosis BILLABLE CODE
        • K74.2 - Hepatic fibrosis with hepatic sclerosis BILLABLE CODE
        • K74.3 - Primary biliary cirrhosis BILLABLE CODE
        • K74.4 - Secondary biliary cirrhosis BILLABLE CODE
        • K74.5 - Biliary cirrhosis, unspecified BILLABLE CODE
        • K74.6 - Other and unspecified cirrhosis of liver NON-BILLABLE CODE
        • K74.60 - Unspecified cirrhosis of liver BILLABLE CODE
        • K74.69 - Other cirrhosis of liver BILLABLE CODE

Clinical Information for Fibrosis and cirrhosis of liver (K74)

Alagille Syndrome - A multisystem disorder that is characterized by aplasia of intrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC), and malformations in the cardiovascular system, the eyes, the vertebral column, and the facies. Major clinical features include JAUNDICE, and congenital heart disease with peripheral PULMONARY STENOSIS. Alagille syndrome may result from heterogeneous gene mutations, including mutations in JAG1 on CHROMOSOME 20 (Type 1) and NOTCH2 on CHROMOSOME 1 (Type 2).

Cholestasis - Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).

Cholestasis, Extrahepatic - Impairment of bile flow in the large BILE DUCTS by mechanical obstruction or stricture due to benign or malignant processes.

Cholestasis, Intrahepatic - Impairment of bile flow due to injury to the HEPATOCYTES; BILE CANALICULI; or the intrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC).

Opisthorchiasis - Infection with flukes of the genus Opisthorchis.

Clonorchiasis - Infection of the biliary passages with CLONORCHIS SINENSIS, also called Opisthorchis sinensis. It may lead to inflammation of the biliary tract, proliferation of biliary epithelium, progressive portal fibrosis, and sometimes bile duct carcinoma. Extension to the liver may lead to fatty changes and cirrhosis. (From Dorland, 27th ed)

Clonorchis sinensis - A species of trematode flukes of the family Opisthorchidae. Many authorities consider this genus belonging to Opisthorchis. It is common in China and other Asiatic countries. Snails and fish are the intermediate hosts.

Bile Ducts - The channels that collect and transport the bile secretion from the BILE CANALICULI, the smallest branch of the BILIARY TRACT in the LIVER, through the bile ductules, the bile ducts out the liver, and to the GALLBLADDER for storage.

Instructional Notations

Code Also Code Also
A "code also" note instructs that two codes may be required to fully describe a condition, but this note does not provide sequencing direction.

• , if applicable, viral hepatitis acute chronic B15 B19

Type 1 Excludes Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.

• alcoholic cirrhosis of liver K70.3
• alcoholic fibrosis of liver K70.2
• cardiac sclerosis of liver K76.1
• cirrhosis of liver with toxic liver disease K71.7
• congenital cirrhosis of liver P78.81
• pigmentary cirrhosis of liver E83.110