Toxic liver disease (K71)
ICD-10 codes in the K71 category are specifically assigned to various forms of toxic liver disease, a condition where the liver is damaged by harmful substances, including drugs and chemicals. These codes help detail the type and severity of liver injury caused by toxins, guiding appropriate healthcare documentation and treatment plans.
The K71 codes cover a range of toxic liver conditions such as toxic liver disease with cholestasis (K71.0), commonly known as drug-induced cholestatic hepatitis, and toxic liver disease with hepatic necrosis (K71.1), which includes acute hepatic failure due to drugs. They also include acute forms like K71.2 (acute toxic hepatitis) and chronic types such as K71.3 to K71.5, which describe persistent or active hepatitis caused by toxins. The category further includes codes for toxic cirrhosis (K71.7) and unspecified toxic liver disease (K71.9), useful when the specific toxic cause or liver pathology is unclear. Incorporating synonyms like drug-induced hepatitis or toxic cirrhosis within coding helps medical coders accurately match clinical terms to the correct ICD-10 code for toxic liver disease.
Diseases of the digestive system (K00–K95)
Diseases of liver (K70-K77)
K71 Toxic liver disease
- K71.0 Toxic liver disease with cholestasis
K71.1 Toxic liver disease with hepatic necrosis
- K71.10 Toxic liver disease with hepatic necrosis, without coma
- K71.11 Toxic liver disease with hepatic necrosis, with coma
- K71.2 Toxic liver disease with acute hepatitis
- K71.3 Toxic liver disease with chronic persistent hepatitis
- K71.4 Toxic liver disease with chronic lobular hepatitis
K71.5 Toxic liver disease with chronic active hepatitis
- K71.50 Toxic liver disease with chronic active hepatitis without ascites
- K71.51 Toxic liver disease with chronic active hepatitis with ascites
- K71.6 Toxic liver disease with hepatitis, not elsewhere classified
- K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
- K71.8 Toxic liver disease with other disorders of liver
- K71.9 Toxic liver disease, unspecified
Toxic liver disease (K71)
Instructional Notations
Includes
This note appears immediately under a three character code title to further define, or give examples of, the content of the category.
- drug-induced idiosyncratic (unpredictable) liver disease
- drug-induced toxic (predictable) liver disease
Code First
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists, there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation.
Use Additional Code
The “use additional code” indicates that a secondary code could be used to further specify the patient’s condition. This note is not mandatory and is only used if enough information is available to assign an additional code.
Type 2 Excludes
A type 2 excludes note represents "Not included here". An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.
Clinical Terms
The following clinical terms provide additional context, helping users better understand the clinical background and common associations for each diagnosis listed in this section. Including related terms alongside ICD-10-CM codes supports coders, billers, and healthcare professionals in improving accuracy, enhancing documentation, and facilitating research or patient education.
Cryptogenic Organizing Pneumonia
An interstitial lung disease of unknown etiology, occurring between 21-80 years of age. It is characterized by a dramatic onset of a pneumonia-like illness with cough, fever, malaise, fatigue, and weight loss. Pathological features include prominent interstitial inflammation without collagen fibrosis, diffuse fibroblastic foci, and no microscopic honeycomb change. There is excessive proliferation of granulation tissue within small airways and alveolar ducts.
