Toxic liver disease (K71) ICD-10-CM
The K71 code range covers toxic liver disease with 15 ICD-10-CM diagnosis codes. 12 of them are billable and valid for claim submission in fiscal year 2026, and the category headers group them but cannot themselves be billed.
Includes
This note appears immediately under a three character code title to further define, or give examples of, the content of the category.
- drug-induced idiosyncratic (unpredictable) liver disease
- drug-induced toxic (predictable) liver disease
Code First
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. For such conditions, the ICD-10-CM has a coding convention that requires the underlying condition be sequenced first followed by the manifestation. Wherever such a combination exists, there is a "use additional code" note at the etiology code, and a "code first" note at the manifestation code. These instructional notes indicate the proper sequencing order of the codes, etiology followed by manifestation.
Use Additional Code
The “use additional code” indicates that a secondary code could be used to further specify the patient’s condition. This note is not mandatory and is only used if enough information is available to assign an additional code.
Type 2 Excludes
A type 2 excludes note represents "Not included here". An excludes2 note indicates that the condition excluded is not part of the condition represented by the code, but a patient may have both conditions at the same time. When an Excludes2 note appears under a code, it is acceptable to use both the code and the excluded code together, when appropriate.
Codes in the K71 Range 15 codes · 12 billable
- K71 Toxic liver diseaseNon-billable
- K71.0 Toxic liver disease with cholestasis
- K71.1 Toxic liver disease with hepatic necrosisNon-billable
- K71.10 Toxic liver disease with hepatic necrosis, without coma
- K71.11 Toxic liver disease with hepatic necrosis, with coma
- K71.2 Toxic liver disease with acute hepatitis
- K71.3 Toxic liver disease with chronic persistent hepatitis
- K71.4 Toxic liver disease with chronic lobular hepatitis
- K71.5 Toxic liver disease with chronic active hepatitisNon-billable
- K71.50 Toxic liver disease with chronic active hepatitis without ascites
- K71.51 Toxic liver disease with chronic active hepatitis with ascites
- K71.6 Toxic liver disease with hepatitis, not elsewhere classified
- K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
- K71.8 Toxic liver disease with other disorders of liver
- K71.9 Toxic liver disease, unspecified
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the K71 range.
Cryptogenic Organizing Pneumonia
An interstitial lung disease of unknown etiology, occurring between 21-80 years of age. It is characterized by a dramatic onset of a pneumonia-like illness with cough, fever, malaise, fatigue, and weight loss. Pathological features include prominent interstitial inflammation without collagen fibrosis, diffuse fibroblastic foci, and no microscopic honeycomb change. There is excessive proliferation of granulation tissue within small airways and alveolar ducts.
About the K71 Code Range
ICD-10 codes in the K71 category are specifically assigned to various forms of toxic liver disease, a condition where the liver is damaged by harmful substances, including drugs and chemicals. These codes help detail the type and severity of liver injury caused by toxins, guiding appropriate healthcare documentation and treatment plans.
The K71 codes cover a range of toxic liver conditions such as toxic liver disease with cholestasis (K71.0), commonly known as drug-induced cholestatic hepatitis, and toxic liver disease with hepatic necrosis (K71.1), which includes acute hepatic failure due to drugs. They also include acute forms like K71.2 (acute toxic hepatitis) and chronic types such as K71.3 to K71.5, which describe persistent or active hepatitis caused by toxins. The category further includes codes for toxic cirrhosis (K71.7) and unspecified toxic liver disease (K71.9), useful when the specific toxic cause or liver pathology is unclear. Incorporating synonyms like drug-induced hepatitis or toxic cirrhosis within coding helps medical coders accurately match clinical terms to the correct ICD-10 code for toxic liver disease.
Questions About This Page
How many billable codes are in the K71 range?
Of the 15 codes in this range, 12 are billable and valid for claim submission from October 1, 2025 through September 30, 2026. Category header codes group them but cannot be reported on claims.
What does the K71 range classify?
The range classifies toxic liver disease. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2026 ICD-10-CM Tabular List and order file, effective October 1, 2025 through September 30, 2026.
