2026 ICD-10-CM Diagnosis Code K72.91Hepatic failure, unspecified with coma

ICD-10-CM Codes›K00–K95›K70-K77›K72

ICD-10-CM K72.91
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

K72.91 is a billable ICD-10-CM diagnosis code for hepatic failure, unspecified with coma. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 441 through 443. Coders also document this condition as chronic viral hepatitis C with hepatic coma. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Coma; stupor; and brain damage and Hepatic failure.

Code Identity

ICD-10-CM Code
K72.91
Billable Status
Yes — Valid for Submission
Code Describes
Hepatic failure, unspecified with coma
Short Description
Hepatic failure, unspecified with coma
Same as the full description in the CMS dataset.
Parent Code
K72.9
Hepatic failure, unspecified

Code Classification

ChapterK00–K95Diseases of the digestive system
SectionK70-K77Diseases of liver
CategoryK72Hepatic failure, not elsewhere classified
This CodeK72.91Hepatic failure, unspecified with coma

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Chronic viral hepatitis C with hepatic coma
  • Hepatic coma due to chronic hepatitis B
  • Hepatic coma due to chronic hepatitis B with delta agent
  • Hepatic coma due to chronic hepatitis C
  • Hepatic coma due to viral hepatitis B
  • Hepatic coma due to viral hepatitis C
  • Hepatic coma due to viral hepatitis D

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Hepatic coma NOS

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Atrophy, atrophic(of)
      • liver (yellow)
        • with coma
    • Failure, failed
      • hepatic
        • with coma
    • Hepatitis
      • malignant NEC (with hepatic failure)
        • with coma
    • Impaired, impairment(function)
      • liver
        • with coma
    • Jaundice(yellow)
      • malignant (without coma)
        • with coma

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NVS013
Coma; stupor; and brain damage
Default principal diagnosis: inpatient No · outpatient No
CCSR DIG018
Hepatic failure
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Coma

A coma is a deep state of unconsciousness. An individual in a coma is alive but unable to move or respond to his or her environment. Coma may occur as a complication of an underlying illness, or as a result of injuries, such as brain injury.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert K72.91 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
572.2 Hepatic encephalopathy
Approximate The match is approximate rather than exact.
ICD-9-CM
572.8 Oth sequela, chr liv dis
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
572.2 Hepatic encephalopathy
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About K72.91Overview

Is K72.91 (Hepatic failure, unspecified) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report hepatic failure, unspecified with coma on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does K72.91 group to?

When hepatic failure, unspecified with coma is the principal diagnosis on an inpatient stay, it groups to MS-DRG 441, 442, 443, with relative weights from 0.6997 to 1.7947 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of K72.91?

Under the General Equivalence Mappings, hepatic failure, unspecified with coma converts to ICD-9-CM 572.2 (hepatic encephalopathy), 572.8 (oth sequela, chr liv dis), and 572.2 (hepatic encephalopathy). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.