2024 ICD-10-CM Diagnosis Code K74.00

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

• Bleeding esophageal varices
• Bleeding esophageal varices due to hepatic fibrosis
• Boichis syndrome
• Congenital hepatic fibrosis
• Esophageal varices associated with another disorder
• Fibrocystic kidney disease
• Fibropolycystic disease of liver
• Hepatic fibrosis
• Hepatic fibrosis due to non-alcoholic fatty liver disease
• Hepatic schistosomiasis
• Liver cyst
• Neonatal diabetes, congenital hypothyroidism, congenital glaucoma, hepatic fibrosis, polycystic kidney syndrome
• Nephronophthisis
• Pericellular fibrosis of congenital syphilis
• Periportal fibrosis
• Periportal fibrosis
• Portal fibrosis without cirrhosis
• Septal fibrosis of liver
• Symmer's pipe-stem fibrosis

Clinical Information

• Nephrocystin-1|Juvenile Nephronophthisis 1 Protein|NPHP1

  nephrocystin-1 (732 aa, ~83 kda) is encoded by the human nphp1 gene. this protein is involved in the modulation of signaling.

• Nephronophthisis

  progressive tubulointerstitial injury, inherited in an autosomal recessive pattern, caused by mutations in genes involved in ciliary function, which may result in an end stage renal failure.

• Nephronophthisis 1|Familial Juvenile Nephronophthisis|Juvenile Nephronophthisis|NPH1

  progressive tubulointerstitial nephritis inherited in an autosomal recessive manner. it is caused by mutations in the nphp1 gene. patients present with anemia, polyuria, and polydipsia during childhood. the progressive bilateral kidney damage results in renal failure.

• NPHP1 Gene|NPHP1|NPHP1|Nephronophthisis 1 (Juvenile) Gene

  this gene is involved in the mediation of signal transduction.

• NPHP1 wt Allele|FLJ97602|JBTS4|NPH1|Nephronophthisis 1 (Juvenile) wt Allele|SLSN1

  human nphp1 wild-type allele is located in the vicinity of 2q13 and is approximately 83 kb in length. this allele, which encodes nephrocystin-1 protein, plays a role in the progression of adhesion-dependent signaling pathways. mutations in the gene are associated with familial juvenile nephronophthisis type 1, senior-loken syndrome type 1, and joubert syndrome type 4.

• Congenital Hepatic Fibrosis

  a congenital disorder usually inherited in an autosomal recessive pattern. it affects the hepatobiliary system and the kidneys. it is characterized by liver fibrosis, portal hypertension, and renal cysts.

Code Edits

The Medicare Code Editor (MCE) detects and reports errors in the coding of claims data. The following ICD-10-CM Code Edits are applicable to this code:

• Unacceptable principal diagnosis - There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

K74.00 is grouped with Diagnostic Related Groups - MS-DRG Mapping

Diagnostic Related Groups (DRGs) are a classification system used to group together diagnosis codes for the purpose of reimbursement and healthcare management. DRGs are used to standardize the way hospitals and other providers are paid for inpatient services. In this system patients are grouped together based on their principal diagnosis in areas referred to as Major Diagnostic Categories (MDC). Once a patient is assigned a particular diagnostic category, providers receive a predetermined payment rate for the services rendered. This reimbursement rate is often fixed and is meant to cover the cost of care for that patient. Reimbursement is also affected by the relative weight of a diagnostic related group based on the severity of a patient's illness and the associated cost of care during hospitalization.

Diagnostic related groups encourage healthcare providers to focus on quality and efficiency in patient care while managing costs effectively. The diagnosis code is present in the following groups for version MS-DRG V41.0 applicable from 10/01/2023 through 09/30/2024.

MS-DRG	MS-DRG Title	MCD	Relative Weight
432	CIRRHOSIS AND ALCOHOLIC HEPATITIS WITH MCC	07	1.916
433	CIRRHOSIS AND ALCOHOLIC HEPATITIS WITH CC	07	1.031
434	CIRRHOSIS AND ALCOHOLIC HEPATITIS WITHOUT CC/MCC	07	0.6695

The relative weight of a diagnostic related group determines the reimbursement rate based on the severity of a patient's illness and the associated cost of care during hospitalization.

Replacement Code

K7400 replaces the following previously assigned ICD-10-CM code(s):

• K74.0 - Hepatic fibrosis

Patient Education

Liver Diseases

Your liver is the largest organ inside your body. It helps your body digest food, store energy, and remove poisons.

There are many kinds of liver diseases:

• Diseases caused by viruses, such as hepatitis A, hepatitis B, and hepatitis C
• Diseases caused by drugs, poisons, or too much alcohol. Examples include fatty liver disease and cirrhosis.
• Liver cancer
• Inherited diseases, such as hemochromatosis and Wilson disease

Symptoms of liver disease can vary, but they often include swelling of the abdomen and legs, bruising easily, changes in the color of your stool and urine, and jaundice, or yellowing of the skin and eyes. Sometimes there are no symptoms. Tests such as imaging tests and liver function tests can check for liver damage and help to diagnose liver diseases.

[Learn More in MedlinePlus]

Code History

• FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
• FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
• FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
• FY 2021 - Code Added, effective from 10/1/2020 through 9/30/2021