2026 ICD-10-CM Diagnosis Code I25.811Atherosclerosis of native coronary artery of transplanted heart without angina pectoris

ICD-10-CM CodesI00–I99I20-I25I25

ICD-10-CM I25.811
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

I25.811 is a billable ICD-10-CM diagnosis code for atherosclerosis of native coronary artery of transplanted heart without angina pectoris. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 302 through 303. Coders also document this condition as accelerated coronary artery disease in transplanted heart. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Coronary atherosclerosis and other heart disease.

This medical diagnosis code is frequently used in Cardiology medical specialties to designate conditions such selected atherosclerosis, ischemia, and infarction.

Code Identity

ICD-10-CM Code
I25.811
Billable Status
Yes — Valid for Submission
Code Describes
Atherosclerosis of native coronary artery of transplanted heart without angina pectoris
Short Description
Athscl native cor art of transplanted heart w/o ang pctrs
Parent Code
Atherosclerosis of other coronary vessels without angina pectoris

Code Classification

ChapterI00–I99Diseases of the circulatory system
SectionI20-I25Ischemic heart diseases
CategoryI25Chronic ischemic heart disease
This CodeI25.811Atherosclerosis of native coronary artery of transplanted heart without angina pectoris

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Accelerated coronary artery disease in transplanted heart
  • Coronary arteriosclerosis in artery of transplanted heart

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Atherosclerosis of native coronary artery of transplanted heart NOS

Type 1 Excludes

  • atherosclerosis of native coronary artery of transplanted heart with angina pectoris I25.75

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Arteriosclerosis, arteriosclerotic(diffuse) (obliterans) (of) (senile) (with calcification)
      • coronary (artery)
        • transplanted heart
    • Arteriosclerosis, arteriosclerotic(diffuse) (obliterans) (of) (senile) (with calcification)
      • coronary (artery)
        • transplanted heart
          • native coronary artery
    • Atherosclerosis
      • transplanted heart
    • Atherosclerosis
      • transplanted heart
        • native coronary artery

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR CIR011
Coronary atherosclerosis and other heart disease
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Atherosclerosis

Atherosclerosis is a condition in which plaque builds up inside your arteries. Plaque is a sticky substance made up of cholesterol, fat, blood cells, calcium, and other substances found in the blood. Over time, plaque hardens and causes your arteries to narrow. That limits the flow of oxygen-rich blood to your body.

The full article covers:

  • What is atherosclerosis?
  • What causes atherosclerosis?
  • Who is more likely to develop atherosclerosis?
  • What are the symptoms of atherosclerosis?
  • What other problems can atherosclerosis cause?
  • How is atherosclerosis diagnosed?
  • What are the treatments for atherosclerosis?
  • Can atherosclerosis be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert I25.811 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
414.06 Cor ath natv art tp hrt
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About I25.811Overview

Is I25.811 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report atherosclerosis of native coronary artery of transplanted heart without angina pectoris on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does I25.811 group to?

When atherosclerosis of native coronary artery of transplanted heart without angina pectoris is the principal diagnosis on an inpatient stay, it groups to MS-DRG 302, 303, with relative weights from 0.6732 to 1.1966 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of I25.811?

Under the General Equivalence Mappings, atherosclerosis of native coronary artery of transplanted heart without angina pectoris converts to ICD-9-CM 414.06 (cor ath natv art tp hrt). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.