2026 ICD-10-CM Diagnosis Code I25.10Atherosclerotic heart disease of native coronary artery without angina pectoris

ICD-10-CM Codes›I00–I99›I20-I25›I25

ICD-10-CM I25.10
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

I25.10 is a billable ICD-10-CM diagnosis code for atherosclerotic heart disease of native coronary artery without angina pectoris. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 302 through 303. The code is restricted by the Medicare Code Editor to adult patients (age 15 through 124). In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Coronary atherosclerosis and other heart disease.

This medical diagnosis code is frequently used in Cardiology medical specialties to designate conditions such selected atherosclerosis, ischemia, and infarction.

Code Identity

ICD-10-CM Code
I25.10
Billable Status
Yes — Valid for Submission
Code Describes
Atherosclerotic heart disease of native coronary artery without angina pectoris
Short Description
Athscl heart disease of native coronary artery w/o ang pctrs
Parent Code
I25.1
Atherosclerotic heart disease of native coronary artery

Code Classification

ChapterI00–I99Diseases of the circulatory system
SectionI20-I25Ischemic heart diseases
CategoryI25Chronic ischemic heart disease
This CodeI25.10Atherosclerotic heart disease of native coronary artery without angina pectoris

Code EditsBilling

Medicare Code Editor checks that affect claim validity for I25.10.

Adult diagnoses
The Medicare Code Editor detects inconsistencies in adult cases by checking a patient's age and any diagnosis on the patient's record. The adult code edits apply to patients age range is 15–124 years inclusive (e.g., senile delirium, mature cataract).

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Atheroma of artery
  • Atherosclerosis of anterior descending branch of left coronary artery
  • Atherosclerosis of circumflex branch of left coronary artery
  • Atherosclerosis of coronary artery without angina pectoris
  • Atherosclerosis of distal portion of right coronary artery
  • Atherosclerosis of left coronary artery
  • Atherosclerosis of left coronary artery main stem
  • Atherosclerosis of mid portion of anterior descending branch of left coronary artery
  • Atherosclerosis of mid portion of circumflex branch of left coronary artery
  • Atherosclerosis of mid portion of right coronary artery
  • Atherosclerosis of proximal portion of anterior descending branch of left coronary artery
  • Atherosclerosis of proximal portion of circumflex branch of left coronary artery
  • Atherosclerosis of proximal portion of right coronary artery
  • Atherosclerosis of right coronary artery
  • Calcific coronary arteriosclerosis
  • Coronary arteriosclerosis
  • Coronary arteriosclerosis caused by radiation
  • Coronary arteriosclerosis in patient with history of previous myocardial infarction
  • Coronary artery atheroma
  • Coronary artery disease due to type 1 diabetes mellitus
  • Coronary artery disease due to type 2 diabetes mellitus
  • Coronary artery stenosis
  • Coronary atherosclerosis
  • Coronary ostium stenosis
  • Coronary stricture
  • Disorder of artery caused by ionizing radiation
  • Double coronary vessel disease
  • Heart disease caused by ionizing radiation
  • Heart failure with normal ejection fraction
  • Heart failure with reduced ejection fraction
  • Heart failure with reduced ejection fraction due to coronary artery disease
  • History of myocardial infarction
  • Ischemic congestive cardiomyopathy
  • Ischemic dilated cardiomyopathy due to coronary artery disease
  • Left main coronary artery disease
  • Left ventricular failure with normal ejection fraction due to coronary artery disease
  • Lipid-rich atherosclerosis of coronary artery
  • Multi vessel coronary artery disease
  • Myocardial infarction due to atherothrombotic coronary artery disease
  • Myocardial ischemia due to coronary arteriosclerosis
  • Non-obstructive atherosclerosis of coronary artery
  • Obliterative coronary artery disease
  • Patient post angioplasty
  • Patient post percutaneous transluminal coronary angioplasty
  • Premature coronary artery disease
  • Recurrent coronary arteriosclerosis after percutaneous transluminal coronary angioplasty
  • Single coronary vessel disease
  • Stenosis of anterior descending branch of left coronary artery
  • Stenosis of circumflex branch of left coronary artery
  • Stenosis of coronary intermediate artery
  • Stenosis of diagonal branch of anterior descending branch of left coronary artery
  • Stenosis of distal portion of anterior descending branch of left coronary artery
  • Stenosis of distal portion of circumflex branch of left coronary artery
  • Stenosis of distal portion of right coronary artery
  • Stenosis of distal segment of left coronary artery main stem
  • Stenosis of left coronary artery main stem
  • Stenosis of left posterior descending circumflex coronary artery
  • Stenosis of left posterior lateral branch of circumflex branch of left coronary artery
  • Stenosis of marginal branch of right coronary artery
  • Stenosis of mid portion of anterior descending branch of left coronary artery
  • Stenosis of mid portion of circumflex branch of left coronary artery
  • Stenosis of mid portion of right coronary artery
  • Stenosis of mid segment of left coronary artery main stem
  • Stenosis of obtuse marginal branch of circumflex branch of left coronary artery
  • Stenosis of ostium of anterior descending branch of left coronary artery
  • Stenosis of ostium of circumflex branch of left coronary artery
  • Stenosis of ostium of left main coronary artery
  • Stenosis of ostium of right coronary artery
  • Stenosis of posterior descending branch of right coronary artery
  • Stenosis of posterior lateral branch of right coronary artery
  • Stenosis of proximal portion of anterior descending branch of left coronary artery
  • Stenosis of proximal portion of circumflex branch of left coronary artery
  • Stenosis of proximal portion of right coronary artery
  • Stenosis of right coronary artery
  • Stenosis of septal branch of anterior descending branch of left coronary artery
  • Stenosis of thoracic aorta
  • Stenotic coronary artery
  • Stricture of artery
  • Triple vessel disease of the heart

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Inclusion Terms

  • Atherosclerotic heart disease NOS

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Arteriosclerosis, arteriosclerotic(diffuse) (obliterans) (of) (senile) (with calcification)
      • coronary (artery)
    • Atheroma, atheromatous
      • coronary (artery)
    • Atherosclerosis
      • coronary
        • artery
    • Disease, diseased
      • artery
        • coronary
    • Disease, diseased
      • cardiovascular (atherosclerotic)
    • Disease, diseased
      • heart (organic)
        • ischemic (chronic or with a stated duration of over 4 weeks)
          • atherosclerotic (of)
    • Sclerosis, sclerotic
      • coronary (artery)

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR CIR011
Coronary atherosclerosis and other heart disease
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Coronary Artery Stenosis

    narrowing of the coronary artery lumen diameter.

  • Left Main Coronary Artery Stenosis

    percent luminal narrowing of the left main coronary artery, at the point of maximal stenosis of the left main coronary artery.

  • Left Main Coronary Artery Stenosis, Percentage

    the percentage of narrowing of the left main coronary artery.

  • Proximal Left Anterior Descending Coronary Artery Stenosis

    a narrowing of the proximal portion of the left main coronary artery, usually considered significant if the stenosis is 70% or greater.

  • Proximal Left Anterior Descending Coronary Artery Stenosis, Percentage

    the percentage narrowing of the proximal portion of the left main coronary artery.

  • Coronary Atherosclerosis

    atherosclerosis of the coronary vasculature.

Patient EducationClinical

Atherosclerosis

Atherosclerosis is a condition in which plaque builds up inside your arteries. Plaque is a sticky substance made up of cholesterol, fat, blood cells, calcium, and other substances found in the blood. Over time, plaque hardens and causes your arteries to narrow. That limits the flow of oxygen-rich blood to your body.

The full article covers:

  • What is atherosclerosis?
  • What causes atherosclerosis?
  • Who is more likely to develop atherosclerosis?
  • What are the symptoms of atherosclerosis?
  • What other problems can atherosclerosis cause?
  • How is atherosclerosis diagnosed?
  • What are the treatments for atherosclerosis?
  • Can atherosclerosis be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert I25.10 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
414.01 Crnry athrscl natve vssl
Approximate The match is approximate rather than exact.
ICD-9-CM
429.2 Ascvd
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About I25.10Overview

Is I25.10 (Atherosclerotic heart disease of native coronary artery) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report atherosclerotic heart disease of native coronary artery without angina pectoris on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does I25.10 group to?

When atherosclerotic heart disease of native coronary artery without angina pectoris is the principal diagnosis on an inpatient stay, it groups to MS-DRG 302, 303, with relative weights from 0.6732 to 1.1966 depending on complications. Higher weights mean higher Medicare reimbursement.

Who can I25.10 be reported for?

The Medicare Code Editor checks atherosclerotic heart disease of native coronary artery without angina pectoris against patient demographics: this code is intended for adult patients (age 15 through 124). Claims outside these limits are flagged as inconsistent.

What is the ICD-9 equivalent of I25.10?

Under the General Equivalence Mappings, atherosclerotic heart disease of native coronary artery without angina pectoris converts to ICD-9-CM 414.01 (crnry athrscl natve vssl) and 429.2 (ascvd). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.