2027 ICD-10-CM Diagnosis Code G60.1Refsum's disease

ICD-10-CM Codes›G00–G99›G60-G65›G60

ICD-10-CM G60.1
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

G60.1 is a billable ICD-10-CM diagnosis code for Refsum's disease. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 91 through 93. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 127 closely related codes. Coders also document this condition as ataxia co-occurrent and due to phytanic acid storage disease. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Polyneuropathies.

G60.1 does not risk-adjust for Medicare Advantage under the CMS-HCC V28 model. It still risk-adjusts in the ESRD (V21) category 75 for payment year 2027.

Code Identity

ICD-10-CM Code
G60.1
Billable Status
Yes — Valid for Submission
Code Describes
Refsum's disease
Short Description
Refsum's disease
Same as the full description in the CMS dataset.
Parent Code
G60
Hereditary and idiopathic neuropathy

Code Classification

ChapterG00–G99Diseases of the nervous system
SectionG60-G65Polyneuropathies and other disorders of the peripheral nervous system
CategoryG60Hereditary and idiopathic neuropathy
This CodeG60.1Refsum's disease

Medicare Risk Adjustment (HCC)Billing

G60.1 does not risk-adjust for Medicare Advantage under the CMS-HCC V28 model, but it maps to payment categories in the other CMS models shown below.

CMS-HCC V28 (Medicare Advantage Payment Model)
Not mapped
no payment category in the model that pays 100% of MA risk scores
Prior Model (CMS-HCC V24)
Not mapped under V24
this diagnosis newly risk-adjusts under the V28 model
Other CMS Models
ESRD (V21): HCC 75
ESRD V21 weights: 0.059 dialysis, 0.284–0.323 functioning graft
Part D (RxHCC)
Not mapped
G60.1 does not risk-adjust in the RxHCC prescription drug model

Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Ataxia co-occurrent and due to phytanic acid storage disease
  • Autonomic neuropathy due to Refsum Disease
  • Dilated cardiomyopathy due to metabolic disorder
  • Dilated cardiomyopathy due to phytanic acid storage disease
  • HSMN IV
  • Infantile Refsum's disease
  • Loss of multiple peroxisomal functions
  • Ophthalmoplegia due to neuropathy
  • Ophthalmoplegia due to phytanic acid storage disease
  • Pseudoinfantile Refsum's disease

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to G60.1: its own notes plus those printed at block G60-G65 and Chapter 6. A note printed at a category, block or chapter applies to every code under it.

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Infantile Refsum disease

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From Block G60-G65 Polyneuropathies and other disorders of the peripheral nervous system applies to 24 codes

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 6 (G00-G99) Diseases of the nervous system applies to 700 codes
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name G60.1, its category, or a range that includes it.

Excludes1 5

These codes carry an Excludes1 note naming G60.1: they are not reported together with it, unless the two conditions are unrelated.

  • E71.3 Disorders of fatty-acid metabolism
    Refsum's disease (G60.1)
  • E71.51 Disorders of peroxisome biogenesis
    Refsum's disease (G60.1)
  • E72.3 Disorders of lysine and hydroxylysine metabolism
    Refsum's disease (G60.1)
  • E75 Disorders of sphingolipid metabolism and other lipid storage disorders
    Refsum's disease (G60.1)
  • Q80 Congenital ichthyosis
    Refsum's disease (G60.1)

Excludes2 1

These codes carry an Excludes2 note naming G60.1: its condition is not part of those codes, and both may be reported when the patient has both.

  • G11 Hereditary ataxia
    hereditary and idiopathic neuropathy (G60.-) names G60.-, which includes this code

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NVS015
Polyneuropathies
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Refsum Disease

    an autosomal recessive familial disorder that usually presents in childhood with polyneuropathy; sensorineural hearing loss; ichthyosis; ataxia; retinitis pigmentosa; and cardiomyopathies. (from joynt, clinical neurology, 1991, ch37, p58-9; rev med interne 1996;17(5):391-8) this condition can be caused by mutation in the genes encoding peroxisomal phytanoyl-coa hydroxylase or proteins associated peroxisomal membrane, leading to impaired catabolism of phytanic acid in peroxisomes.

Patient EducationClinical

Peripheral Nerve Disorders

Nerves are like wires that carry messages back and forth between your brain and your body. Your peripheral nerves branch off from your brain and spinal cord and connect to all parts of your body, including your muscles and organs.

The full article covers:

  • What are peripheral nerves?
  • What are peripheral nerve disorders?
  • What causes peripheral nerve disorders?
  • What are the symptoms of peripheral nerve disorders?
  • How are peripheral nerve disorders diagnosed?
  • What are the treatments for peripheral nerve disorders?
  • Can peripheral nerve disorders be prevented?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert G60.1 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
356.3 Refsum's disease
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About G60.1Overview

What is the ICD-10 code for Refsum's disease?

The ICD-10-CM code for Refsum's disease is G60.1 (sometimes written as G601). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is G60.1 (Hereditary and idiopathic neuropathy) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report Refsum's disease on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does G60.1 group to?

When Refsum's disease is the principal diagnosis on an inpatient stay, it groups to MS-DRG 91, 92, 93, with relative weights from 0.7783 to 1.7050 depending on complications. Higher weights mean higher Medicare reimbursement.

Is G60.1 a CC or MCC?

CMS lists G60.1 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 127 closely related codes in its exclusion list.

Can G60.1 be reported with M79.2?

Not as a rule. The Excludes1 note at block G60-G65, which applies to G60.1, lists "neuralgia NOS (M79.2)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

Does G60.1 risk-adjust for Medicare Advantage payment?

Not for Medicare Advantage: G60.1 maps to no category in the CMS-HCC V28 model. It still risk-adjusts in the ESRD (V21) category 75 (Polyneuropathy).