Inflammatory polyneuropathy (G61) ICD-10-CM
The G61 code range covers inflammatory polyneuropathy with 8 ICD-10-CM diagnosis codes. 6 of them are billable and valid for claim submission in fiscal year 2026, and the category headers group them but cannot themselves be billed.
Codes in the G61 Range 8 codes · 6 billable
- G61 Inflammatory polyneuropathyNon-billable
- G61.0 Guillain-Barre syndrome
- G61.1 Serum neuropathy
- G61.8 Other inflammatory polyneuropathiesNon-billable
- G61.81 Chronic inflammatory demyelinating polyneuritis
- G61.82 Multifocal motor neuropathy
- G61.89 Other inflammatory polyneuropathies
- G61.9 Inflammatory polyneuropathy, unspecified
Clinical Terms in This Code Range
Definitions from the National Library of Medicine for conditions coded in the G61 range.
Guillain-Barre Syndrome
An acute inflammatory autoimmune neuritis caused by T cell- mediated cellular immune response directed towards peripheral myelin. Demyelination occurs in peripheral nerves and nerve roots. The process is often preceded by a viral or bacterial infection, surgery, immunization, lymphoma, or exposure to toxins. Common clinical manifestations include progressive weakness, loss of sensation, and loss of deep tendon reflexes. Weakness of respiratory muscles and autonomic dysfunction may occur. (From Adams et al., Principles of Neurology, 6th ed, pp1312-1314)
Polyradiculoneuropathy
Diseases characterized by injury or dysfunction involving multiple peripheral nerves and nerve roots. The process may primarily affect myelin or nerve axons. Two of the more common demyelinating forms are acute inflammatory polyradiculopathy (GUILLAIN-BARRE SYNDROME) and POLYRADICULONEUROPATHY, CHRONIC INFLAMMATORY DEMYELINATING. Polyradiculoneuritis refers to inflammation of multiple peripheral nerves and spinal nerve roots.
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating
A slowly progressive autoimmune demyelinating disease of peripheral nerves and nerve roots. Clinical manifestations include weakness and sensory loss in the extremities and enlargement of peripheral nerves. The course may be relapsing-remitting or demonstrate a step-wise progression. Protein is usually elevated in the spinal fluid and cranial nerves are typically spared. GUILLAIN-BARRE SYNDROME features a relatively rapid progression of disease which distinguishes it from this condition. (Adams et al., Principles of Neurology, 6th ed, p1337)
About the G61 Code Range
The ICD-10 code G61 series covers various types of inflammatory polyneuropathies, conditions involving inflammation of multiple peripheral nerves. These codes are used to specifically identify and classify disorders such as Guillain-Barré syndrome, chronic inflammatory demyelinating polyneuritis, and other related neuropathies.
The ICD-10 code for Guillain-Barré syndrome (G61.0) includes many synonyms like acute inflammatory demyelinating polyradiculoneuropathy and post-infectious polyneuritis, reflecting its autoimmune nature affecting the nerves. Chronic inflammatory demyelinating polyneuritis (G61.81) captures long-term immune-mediated nerve damage, sometimes referred to as chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Codes like G61.82 for multifocal motor neuropathy and G61.89 for other inflammatory polyneuropathies help distinguish among varied nerve inflammation disorders with different clinical presentations. When the specific type can’t be determined, G61.9 is used for unspecified inflammatory polyneuropathy, often called polyneuritis. These detailed ICD-10 designations ensure accurate coding for inflammatory nerve diseases, improving diagnostic clarity and facilitating proper management.
Questions About This Page
How many billable codes are in the G61 range?
Of the 8 codes in this range, 6 are billable and valid for claim submission from October 1, 2025 through September 30, 2026. Category header codes group them but cannot be reported on claims.
What does the G61 range classify?
The range classifies inflammatory polyneuropathy. Each code links to its own reference page with billing status, MS-DRG grouping, coding notes, and clinical information.
Related References
Source: CMS FY 2026 ICD-10-CM Tabular List and order file, effective October 1, 2025 through September 30, 2026.
