2027 ICD-10-CM Diagnosis Code G37.0Diffuse sclerosis of central nervous system

ICD-10-CM Codes›G00–G99›G35-G37›G37

ICD-10-CM G37.0
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

G37.0 is a billable ICD-10-CM diagnosis code for diffuse sclerosis of central nervous system. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 58 through 60. As a secondary diagnosis, it counts as a complication or comorbidity (CC) and moves an inpatient stay to a higher severity level within its MS-DRG family. It does not count, however, when the principal diagnosis is one of 13 closely related codes. Coders also document this condition as Schilder's disease. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other nervous system disorders (neither hereditary nor degenerative).

For Medicare Advantage risk adjustment, G37.0 maps to CMS-HCC Category 198 (Multiple Sclerosis) under the V28 model, adding a risk factor of about 0.647 for a community, non-dual, aged beneficiary in payment year 2027.

Code Identity

ICD-10-CM Code
G37.0
Billable Status
Yes — Valid for Submission
Code Describes
Diffuse sclerosis of central nervous system
Short Description
Diffuse sclerosis of central nervous system
Same as the full description in the CMS dataset.
Parent Code
G37
Other demyelinating diseases of central nervous system

Code Classification

ChapterG00–G99Diseases of the nervous system
SectionG35-G37Demyelinating diseases of the central nervous system
CategoryG37Other demyelinating diseases of central nervous system
This CodeG37.0Diffuse sclerosis of central nervous system

Medicare Risk Adjustment (HCC)Billing

G37.0 maps to a payment category in the CMS-HCC model used to risk-adjust Medicare Advantage payments. Weights are the published community factors for payment year 2027.

CMS-HCC V28 Category (Payment Model)
HCC 198— Multiple Sclerosis
Payment HCC · PY 2027 one of 20 ICD-10-CM codes in this category
Risk Adjustment Factor (RAF) Weight
+0.647
community, non-dual, aged · ranges 0.226–1.143 across segments
Hierarchy
Top of its hierarchy
HCC 198 is not superseded by any other condition category
Prior Model (CMS-HCC V24)
HCC 77
V24 retired V28 pays 100% of MA risk scores since PY 2026
Other CMS Models
PACE (CMS-HCC V22): HCC 77 · ESRD (V21): HCC 77 · ESRD (V24): HCC 77
ESRD V21 weights: 0.069 dialysis, 0.000–0.546 functioning graft · ESRD V24 weights: 0.111 dialysis, 0.042–1.113 functioning graft
Part D (RxHCC)
RxHCC 159 — Multiple Sclerosis
also risk-adjusts in the Part D prescription drug model (V08)

Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Schilder's disease

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to G37.0: its own notes plus those printed at Chapter 6. A note printed at a category, block or chapter applies to every code under it.

Applicable To

Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.

  • Periaxial encephalitis
  • Schilder's disease

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

  • X linked adrenoleukodystrophy (E71.52-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Chapter 6 (G00-G99) Diseases of the nervous system applies to 700 codes
  • certain conditions originating in the perinatal period (P04-P96)
  • certain infectious and parasitic diseases (A00-B99)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations, and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name G37.0, its category, or a range that includes it.

Excludes1 2

These codes carry an Excludes1 note naming G37.0: they are not reported together with it, unless the two conditions are unrelated.

  • E71.3 Disorders of fatty-acid metabolism
    Schilder's disease (G37.0)
  • E71.5 Peroxisomal disorders
    Schilder's disease (G37.0)

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NVS020
Other nervous system disorders (neither hereditary nor degenerative)
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Diffuse Cerebral Sclerosis of Schilder

    a rare central nervous system demyelinating condition affecting children and young adults. pathologic findings include a large, sharply defined, asymmetric focus of myelin destruction that may involve an entire lobe or cerebral hemisphere. the clinical course tends to be progressive and includes dementia, cortical blindness, cortical deafness, spastic hemiplegia, and pseudobulbar palsy. concentric sclerosis of balo is differentiated from diffuse cerebral sclerosis of schilder by the pathologic finding of alternating bands of destruction and preservation of myelin in concentric rings. alpers' syndrome refers to a heterogeneous group of diseases that feature progressive cerebral deterioration and liver disease. (from adams et al., principles of neurology, 6th ed, p914; dev neurosci 1991;13(4-5):267-73)

Patient EducationClinical

Degenerative Nerve Diseases

Degenerative nerve diseases affect many of your body's activities, such as balance, movement, talking, breathing, and heart function. Many of these diseases are genetic. Sometimes the cause is a medical condition such as alcoholism, a tumor, or a stroke. Other causes may include toxins, chemicals, and viruses.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert G37.0 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
341.1 Schilder's disease
Approximate The match is approximate rather than exact.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About G37.0Overview

What is the ICD-10 code for diffuse sclerosis of central nervous system?

The ICD-10-CM code for diffuse sclerosis of central nervous system is G37.0 (sometimes written as G370). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

Is G37.0 (Other demyelinating diseases of central nervous system) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report diffuse sclerosis of central nervous system on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What MS-DRG does G37.0 group to?

When diffuse sclerosis of central nervous system is the principal diagnosis on an inpatient stay, it groups to MS-DRG 60, 58, 59, with relative weights from 0.9248 to 1.8430 depending on complications. Higher weights mean higher Medicare reimbursement.

Is G37.0 a CC or MCC?

CMS lists G37.0 as a CC (complication or comorbidity) for FY 2027. Reported as a secondary diagnosis, it moves the inpatient stay to a higher-weighted DRG within its severity family. It does not count when the principal diagnosis is one of the 13 closely related codes in its exclusion list.

Can G37.0 be reported with a code from E71.52?

Not as a rule. The Excludes1 note on G37.0 lists "X linked adrenoleukodystrophy (E71.52-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What HCC is G37.0?

G37.0 (diffuse sclerosis of central nervous system) maps to CMS-HCC Category 198 (Multiple Sclerosis), commonly written as HCC 198, in the CMS-HCC V28 model used for Medicare Advantage risk adjustment in payment year 2027. It mapped to HCC 77 under the retired V24 model. It also maps in the PACE (CMS-HCC V22), ESRD (V21), and ESRD (V24) models. In the Part D prescription drug model it maps to RxHCC 159.

Does G37.0 risk-adjust for Medicare Advantage payment?

Yes. When documented and reported on a Medicare Advantage encounter, G37.0 adds a risk adjustment factor of about 0.647 to the beneficiary's RAF score for a community, non-dual, aged enrollee (published V28 weights range from 0.226 to 1.143 depending on the payment segment). HCC 198 sits at the top of its hierarchy, so no other condition category supersedes it. See the full factor table on the HCC 198 category page.