2025 ICD-10-CM Diagnosis Code E15
Nondiabetic hypoglycemic coma
- ICD-10-CM Code:
- E15
- ICD-10 Code for:
- Nondiabetic hypoglycemic coma
- Is Billable?
- Yes - Valid for Submission
- Chronic Condition Indicator: [1]
- Not chronic
- Code Navigator:
E15 is a billable diagnosis code used to specify a medical diagnosis of nondiabetic hypoglycemic coma. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2024 through September 30, 2025.
Approximate Synonyms
The following list of clinical terms are approximate synonyms, alternative descriptions, or common phrases that might be used by patients, healthcare providers, or medical coders to describe the same condition. These synonyms and related diagnosis terms are often used when searching for an ICD-10 code, especially when the exact medical terminology is unclear. Whether you're looking for lay terms, similar diagnosis names, or common language alternatives, this list can help guide you to the correct ICD-10 classification.
- Drug-induced coma
- Drug-induced coma
- Drug-induced insulin coma in nondiabetic
- Hypoglycemic coma
- Insulin coma
- Non-diabetic hypoglycemic coma
Clinical Classification
Clinical Classifications group individual ICD-10-CM diagnosis codes into broader, clinically meaningful categories. These categories help simplify complex data by organizing related conditions under common clinical themes.
They are especially useful for data analysis, reporting, and clinical decision-making. Even when diagnosis codes differ, similar conditions can be grouped together based on their clinical relevance. Each category is assigned a unique CCSR code that represents a specific clinical concept, often tied to a body system or medical specialty.
Coma; stupor; and brain damage
CCSR Code: NVS013
Inpatient Default: N - Not default inpatient assignment for principal diagnosis or first-listed diagnosis.
Outpatient Default: N - Not default outpatient assignment for principal diagnosis or first-listed diagnosis.
Other specified and unspecified endocrine disorders
CCSR Code: END015
Inpatient Default: Y - Yes, default inpatient assignment for principal diagnosis or first-listed diagnosis.
Outpatient Default: Y - Yes, default outpatient assignment for principal diagnosis or first-listed diagnosis.
Clinical Information
Convulsive Therapy
convulsions induced in order to treat mental disorders. it is used primarily in the treatment of severe affective disorders and schizophrenia.Insulin Coma
severe hypoglycemia induced by a large dose of exogenous insulin resulting in a coma or profound state of unconsciousness from which the individual cannot be aroused.Insulin Coma
a hypoglycemia-induced comatose state resulting from a large dose of exogenous insulin.Hypoglycemic Coma
a comatose state attributable to abnormally low serum glucose levels.
Tabular List of Diseases and Injuries
The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.
Includes
IncludesThis note appears immediately under a three character code title to further define, or give examples of, the content of the category.
- drug-induced insulin coma in nondiabetic
- hyperinsulinism with hypoglycemic coma
- hypoglycemic coma NOS
Index to Diseases and Injuries References
The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).
- - Coma - R40.20
- - hypoglycemic (diabetic) - See: Diabetes, by type, with hypoglycemia, with coma;
- - nondiabetic - E15
- - hypoglycemic (diabetic) - See: Diabetes, by type, with hypoglycemia, with coma;
- - Hyperinsulinism (functional) - E16.1
- - with
- - coma (hypoglycemic) - E15
- - with
- - Hypoglycemia (spontaneous) - E16.2
- - coma - E15
- - drug-induced - E16.0
- - with coma (nondiabetic) - E15
- - due to insulin - E16.0
- - with coma (nondiabetic) - E15
- - iatrogenic - E16.0
- - with coma (nondiabetic) - E15
- - Reaction - See Also: Disorder;
- - hypoglycemic, due to insulin - E16.0
- - with coma (diabetic) - See: Diabetes, coma;
- - nondiabetic - E15
- - with coma (diabetic) - See: Diabetes, coma;
- - hypoglycemic, due to insulin - E16.0
Convert E15 to ICD-9-CM
Below are the ICD-9 codes that most closely match this ICD-10 code, based on the General Equivalence Mappings (GEMs). This ICD-10 to ICD-9 crosswalk tool is helpful for coders who need to reference legacy diagnosis codes for audits, historical claims, or approximate code comparisons.
Hypoglycemic coma
ICD-9-CM: 251.0
This is a direct match with no additional mapping qualifiers. The absence of a flag generally means the mapping is considered exact or precise. In other words, the ICD-10 code maps cleanly to the ICD-9 code without qualification, approximation, or needing multiple codes.
Patient Education
Coma
A coma is a deep state of unconsciousness. An individual in a coma is alive but unable to move or respond to his or her environment. Coma may occur as a complication of an underlying illness, or as a result of injuries, such as brain injury.
A coma rarely lasts more than 2 to 4 weeks. The outcome for coma depends on the cause, severity, and site of the damage. People may come out of a coma with physical, intellectual, and psychological problems. Some people may remain in a coma for years or even decades. For those people, the most common cause of death is infection, such as pneumonia.
NIH: National Institute of Neurological Disorders and Stroke
[Learn More in MedlinePlus]
Hypoglycemia
What is blood glucose?
Blood glucose, or blood sugar, is the main sugar found in your blood. It is your body's primary source of energy. It comes from the food you eat. Your body breaks down most of that food into glucose and releases it into your bloodstream. When your blood glucose goes up, it signals your pancreas to release insulin. Insulin is a hormone that helps the glucose get into your cells to be used for energy.
For people with diabetes, your body doesn't make enough insulin, can't use it as well as it should, or both. Too much glucose stays in your blood and doesn't reach your cells.
What is hypoglycemia?
Hypoglycemia means low glucose. It happens when the level of glucose in your blood drops below what is healthy for you:
- For many people with diabetes, this means a blood glucose level lower than 70 mg/dL. Your number might be different, so check with your health care team to find out what blood glucose level is too low for you.
- For people who don't have diabetes, hypoglycemia is typically a blood glucose level lower than 55 mg/dL.
What causes hypoglycemia?
Hypoglycemia is common in people who have diabetes type 1 or who have diabetes type 2 and take insulin or other diabetes medicines. It can happen:
- As a side effect of insulin or some other medicines that help your pancreas release insulin into your blood. These medicines can lower your blood glucose level.
- If you don't eat or drink enough carbohydrates (carbs). Carbs are the main source of glucose for your body.
- If you get a lot more physical activity than usual.
- If you drink too much alcohol without enough food.
- When you are sick and can't eat enough food or keep food down.
Although it's rare, you can still get low blood glucose without having diabetes. The causes can include conditions such as liver disease, kidney disease, and hormone deficiencies (lack of certain hormones). It can also happen in people who have had certain types of weight loss surgery. Some medicines, such as certain heart medicines and antibiotics, can also cause it. See your health care provider to find out the cause of your low blood glucose and how to treat it.
What are the symptoms of hypoglycemia?
The symptoms of low blood glucose tend to come on quickly. The symptoms can be different for everyone, but they may include:
- Shaking
- Sweating
- Nervousness or anxiety
- Irritability or confusion
- Dizziness
- Hunger
How is hypoglycemia diagnosed?
If you have diabetes, you'll most likely need to check your blood glucose every day and make sure that it's not too low. You can do this with a blood glucose meter or continuous glucose monitoring (CGM) system.
There are also blood tests that providers can use to check if your blood glucose is too low.
If you don't have diabetes and you have hypoglycemia, your provider will likely order other tests to try to figure out the cause.
What are the treatments for hypoglycemia?
If you have mild or moderate hypoglycemia, eating or drinking something with carbohydrates can help. But severe hypoglycemia can cause serious complications, including passing out, coma, or even death. Severe hypoglycemia can be treated with glucagon, a hormone that raises blood glucose levels. It can be given as nasal spray or injection. If you have diabetes, your provider can prescribe you a glucagon kit for use in case of an emergency.
If you have diabetes and you often have mild or moderate low blood glucose, your health care team may make changes to your diabetes meal plan, physical activity plan, and/or diabetes medicines.
If you don't have diabetes and you keep having low blood glucose, the treatment will depend on what is causing it to happen.
Can hypoglycemia be prevented?
If you have diabetes and you take insulin or other medicines that lower blood glucose, you can help prevent hypoglycemia if you:
- Follow your diabetes meal plan. Eat and drink enough carbs to keep your blood glucose in your target range. Also carry a source of fast-acting carbohydrate, such as glucose tablets or a juice box, with you in case your blood glucose gets too low.
- Be safe during physical activity. Check your blood glucose before and afterwards. You may need to eat a snack before your physical activity.
- If you take diabetes medicines, make sure to take them correctly.
[Learn More in MedlinePlus]
Code History
- FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
- FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
- FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
- FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
- FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
- FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
- FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
- FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
- FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.
Footnotes
[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.