E16.4 - Increased secretion of gastrin
| ICD-10: | E16.4 |
| Short Description: | Increased secretion of gastrin |
| Long Description: | Increased secretion of gastrin |
| Status: | Valid for Submission |
| Version: | ICD-10-CM 2023 |
| Code Classification: |
E16.4 is a billable ICD-10 code used to specify a medical diagnosis of increased secretion of gastrin. The code is valid during the fiscal year 2023 from October 01, 2022 through September 30, 2023 for the submission of HIPAA-covered transactions.
Approximate Synonyms
The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:
- Abnormal hormone secretion
- Abnormality of secretion of gastrin
- Anastomotic ulcer due to Zollinger-Ellison syndrome
- Drug-induced hypergastrinemia
- Duodenal ulcer due to Zollinger-Ellison syndrome
- Familial hypergastrinemic duodenal ulcer
- Gastric ulcer due to Zollinger-Ellison syndrome
- Gastrinoma
- Hyperplasia of islet alpha cells with gastrin excess
- Impaired acid inhibition of gastrin release
- Increased gastrin secretion
- Islet cell hyperplasia
- Megaloblastic anemia due to Zollinger-Ellison syndrome
- Zollinger-Ellison syndrome
Clinical Information
- Gastrinoma-. a gastrin-secreting neuroendocrine tumor of the non-beta islet cells, the gastrin-secreting cells. this type of tumor is primarily located in the pancreas or the duodenum. majority of gastrinomas are malignant. they metastasize to the liver; lymph nodes; and bone but rarely elsewhere. the presence of gastrinoma is one of three requirements to be met for identification of zollinger-ellison syndrome, which sometimes occurs in families with multiple endocrine neoplasia type 1; (men 1).
Tabular List of Diseases and Injuries
The Tabular List of Diseases and Injuries is a list of ICD-10 codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more. The following references are applicable to this diagnosis code:
Inclusion Terms
Inclusion TermsThese terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
- Hypergastrinemia
- Hyperplasia of pancreatic endocrine cells with gastrin excess
- Zollinger-Ellison syndrome
Index to Diseases and Injuries References
The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for this diagnosis code are found in the injuries and diseases index:
- - Abnormal, abnormality, abnormalities - See Also: Anomaly;
- - gastrin secretion - E16.4
- - secretion
- - gastrin - E16.4
- - Ellison-Zollinger syndrome - E16.4
- - Hypergastrinemia - E16.4
- - Hyperplasia, hyperplastic
- - pancreatic islet cells - E16.9
- - alpha - E16.8
- - with excess
- - gastrin - E16.4
- - with excess
- - alpha - E16.8
- - pancreatic islet cells - E16.9
- - Hypersecretion
- - gastrin - E16.4
- - Zollinger-Ellison syndrome - E16.4
Convert to ICD-9 Code
| Source ICD-10 Code | Target ICD-9 Code | |
|---|---|---|
| E16.4 | 251.5 - Abnorm secretion gastrin |
Patient Education
Pancreatic Diseases
The pancreas is a gland behind your stomach and in front of your spine. It produces juices that help break down food and hormones that help control blood sugar levels. Problems with the pancreas can lead to many health problems. These include:
- Pancreatitis, or inflammation of the pancreas: This happens when digestive enzymes start digesting the pancreas itself
- Pancreatic cancer
- Cystic fibrosis, a genetic disorder in which thick, sticky mucus can also block tubes in your pancreas
The pancreas also plays a role in diabetes. In type 1 diabetes, the beta cells of the pancreas no longer make insulin because the body's immune system has attacked them. In type 2 diabetes, the pancreas loses the ability to secrete enough insulin in response to meals.
[Learn More in MedlinePlus]
Zollinger-Ellison Syndrome
Learn about Zollinger-Ellison syndrome, in which tumors in the pancreas or duodenum increase stomach acid, leading to peptic ulcers, acid reflux, and diarrhea.[Learn More in MedlinePlus]
Code History
- FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
- FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
- FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
- FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
- FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
- FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
- FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
- FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016 (First year ICD-10-CM implemented into the HIPAA code set)