2027 ICD-10-CM Diagnosis Code E00.2Congenital iodine-deficiency syndrome, mixed type
ICD-10-CM Codes›E00–E89›E00-E07›E00
- Billable — Valid for Submission
- Chronic Condition
E00.2 is a billable ICD-10-CM diagnosis code for congenital iodine-deficiency syndrome, mixed type. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 643 through 645. Coders also document this condition as congenital iodine deficiency syndrome. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Thyroid disorders.
E00.2 does not risk-adjust for Medicare Advantage under the CMS-HCC V28 model. It still risk-adjusts in the RxHCC Part D (V08) category 44 for payment year 2027.
Code Identity
Code Classification
Medicare Risk Adjustment (HCC)Billing
E00.2 does not risk-adjust for Medicare Advantage under the CMS-HCC V28 model, but it maps to payment categories in the other CMS models shown below.
Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Congenital iodine deficiency syndrome
- Congenital iodine deficiency syndrome of mixed type
- Congenital iodine deficiency syndrome of neurological type
- Endemic congenital iodine deficiency syndrome of myxedematous type
- Endemic cretinism
- Multiple malformation syndrome due to non-infectious environmental agents
- Myxedema
- Myxedematous form of cretinism
Instructional NotesGuidance
Instructions from the official ICD-10-CM Tabular List that apply to E00.2: its own notes plus those printed at E00 and Chapter 4. A note printed at a category, block or chapter applies to every code under it.
Applicable To
Conditions this code is used for: synonyms of the title or, for "other specified" codes, the conditions assigned to it. The list is not exhaustive.
- Endemic cretinism, mixed type
Excludes1
Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.
- subclinical iodine-deficiency hypothyroidism (E02)
Use Additional Code
Add a second code, after this one, to fully describe the condition.
Notes
General instructions on how these codes are used.
- All neoplasms, whether functionally active or not, are classified in Chapter 2. Appropriate codes in this chapter (i.e. E05.8, E07.0, E16-E31, E34.-) may be used as additional codes to indicate either functional activity by neoplasms and ectopic endocrine tissue or hyperfunction and hypofunction of endocrine glands associated with neoplasms and other conditions classified elsewhere.
Source: CMS ICD-10-CM Tabular List. How to read instructional notes.
Referenced in Other NotesGuidance
Instructional notes printed at other codes that name E00.2, its category, or a range that includes it.
Applicable To 1
These notes mention E00.2.
- Z83.4 Family history of other endocrine, nutritional and metabolic diseases
Excludes1 4
These codes carry an Excludes1 note naming E00.2: they are not reported together with it, unless the two conditions are unrelated.
Excludes2 1
These codes carry an Excludes2 note naming E00.2: its condition is not part of those codes, and both may be reported when the patient has both.
- Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
Code First 5
These codes say to code first a condition named in the note, and E00.2 is one of the conditions named.
- D63.8 Anemia in other chronic diseases classified elsewhere
- F02 Dementia in other diseases classified elsewhere
- G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere
- G63 Polyneuropathy in diseases classified elsewhere
- M14.8 Arthropathies in other specified diseases classified elsewhere
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
Syndrome See Also: Disease;
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Congenital Iodine Deficiency Syndrome, Mixed Type
congenital iodine deficiency syndrome associated with overlapping features of both the neurological and myxedematous variants.
Patient EducationClinical
Thyroid Diseases
Your thyroid is a small, butterfly-shaped gland in the front of your neck. It makes hormones that control the way the body uses energy. These hormones affect nearly every organ in your body and control many of your body's most important functions. For example, they affect your breathing, heart rate, weight, digestion, and moods.
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert E00.2 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About E00.2Overview
What is the ICD-10 code for congenital iodine-deficiency syndrome, mixed type?
The ICD-10-CM code for congenital iodine-deficiency syndrome, mixed type is E00.2 (sometimes written as E002). It is billable on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
Is E00.2 (Congenital iodine-deficiency syndrome) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report congenital iodine-deficiency syndrome, mixed type on HIPAA-covered claims from October 1, 2026 through September 30, 2027.
What MS-DRG does E00.2 group to?
When congenital iodine-deficiency syndrome, mixed type is the principal diagnosis on an inpatient stay, it groups to MS-DRG 644, 645, 643, with relative weights from 0.7461 to 1.6138 depending on complications. Higher weights mean higher Medicare reimbursement.
Can E00.2 be reported with E02?
Not as a rule. The Excludes1 note at E00, which applies to E00.2, lists "subclinical iodine-deficiency hypothyroidism (E02)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).
Does E00.2 need an additional code?
When the condition applies, yes. The Use Additional Code note at E00, which applies to E00.2, reads: code (F70-F79) to identify associated intellectual disabilities.. The additional code is reported after E00.2.
Does E00.2 risk-adjust for Medicare Advantage payment?
Not for Medicare Advantage: E00.2 maps to no category in the CMS-HCC V28 model. It still risk-adjusts in the RxHCC Part D (V08) category 44 (Thyroid Disorders).
