2024 ICD-10-CM Diagnosis Code D89.839

Cytokine release syndrome, grade unspecified

ICD-10-CM Code:
D89.839
ICD-10 Code for:
Cytokine release syndrome, grade unspecified
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Not chronic
Code Navigator:

Code Classification

  • Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
    (D50–D89)
    • Certain disorders involving the immune mechanism
      (D80-D89)
      • Other disorders involving the immune mechanism, not elsewhere classified
        (D89)

D89.839 is a billable diagnosis code used to specify a medical diagnosis of cytokine release syndrome, grade unspecified. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.

This code describes a circumstance which influences the patient's health status but not a current illness or injury. The code is unacceptable as a principal diagnosis.

Unspecified diagnosis codes like D89.839 are acceptable when clinical information is unknown or not available about a particular condition. Although a more specific code is preferable, unspecified codes should be used when such codes most accurately reflect what is known about a patient's condition. Specific diagnosis codes should not be used if not supported by the patient's medical record.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Cytokine release syndrome
  • Cytokine release syndrome
  • Cytokine release syndrome due to chimeric antigen receptor T-cell immunotherapy
  • Immune system complication of procedure

Clinical Classification

Clinical Information

  • Cytokine Release Syndrome

    a severe immune reaction characterized by excessive release of cytokines. symptoms include dyspnea; fever; headache; hypotension; nausea; rash; tachycardia; hypoxia; hyperferritinemia, and multiple organ failure. it is associated with viral infections, sepsis; autoimmune diseases and a variety of factors used in immunotherapy.

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Code Edits

The Medicare Code Editor (MCE) detects and reports errors in the coding of claims data. The following ICD-10-CM Code Edits are applicable to this code:

  • Unacceptable principal diagnosis - There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Replacement Code

D89839 replaces the following previously assigned ICD-10-CM code(s):

  • D89.89 - Oth disrd involving the immune mechanism, NEC

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - Code Added, effective from 10/1/2020 through 9/30/2021

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.