2026 ICD-10-CM Diagnosis Code D78.33Postprocedural seroma of the spleen following a procedure on the spleen

ICD-10-CM Codes›D50–D89›D78›D78

ICD-10-CM D78.33
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D78.33 is a billable ICD-10-CM diagnosis code for postprocedural seroma of the spleen following a procedure on the spleen. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 919 through 921. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Postprocedural or postoperative complications of the spleen.

Code Identity

ICD-10-CM Code
D78.33
Billable Status
Yes — Valid for Submission
Code Describes
Postprocedural seroma of the spleen following a procedure on the spleen
Short Description
Postprocedural seroma of the spleen fol proc on spleen
Parent Code
D78.3
Postprocedural hematoma and seroma of the spleen following a procedure

Code Classification

ChapterD50–D89Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
SectionD78Intraoperative and postprocedural complications of the spleen
CategoryD78Intraoperative and postprocedural complications of the spleen
This CodeD78.33Postprocedural seroma of the spleen following a procedure on the spleen

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Complication(s) (from) (of)
      • postprocedural
        • seroma (of)
          • spleen
            • following procedure on the spleen

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR BLD009
Postprocedural or postoperative complications of the spleen
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Spleen Diseases

Your spleen is an organ above your stomach and under your ribs on your left side. It is about as big as your fist. The spleen is part of your lymphatic system, which fights infection and keeps your body fluids in balance. It contains white blood cells that fight germs.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert D78.33 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
998.13 Seroma complicting proc
Approximate The match is approximate rather than exact.

Code History & ChangesHistory

Replacement D78.33 replaces the following previously assigned code(s):

  • D78.21 - Postprocedural hemor/hemtom of the spleen fol proc on spleen
  • D78.21 - Postprocedural hemorrhage of the spleen fol proc on spleen
FY 2018AddedAdded to the ICD-10-CM code setEffective October 1, 2017.
FY 2019–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D78.33Overview

Is D78.33 a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report postprocedural seroma of the spleen following a procedure on the spleen on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D78.33 group to?

When postprocedural seroma of the spleen following a procedure on the spleen is the principal diagnosis on an inpatient stay, it groups to MS-DRG 919, 920, 921, with relative weights from 0.6884 to 1.8308 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of D78.33?

Under the General Equivalence Mappings, postprocedural seroma of the spleen following a procedure on the spleen converts to ICD-9-CM 998.13 (seroma complicting proc). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.