ICD-10-CM Code D80.2

Selective deficiency of immunoglobulin A [IgA]

Version 2021 Billable Code

Valid for Submission

D80.2 is a billable code used to specify a medical diagnosis of selective deficiency of immunoglobulin a [iga]. The code is valid for the fiscal year 2021 for the submission of HIPAA-covered transactions. The ICD-10-CM code D80.2 might also be used to specify conditions or terms like abnormal alpha globulin level, chromosome 22 abnormalities with hypogammaglobulinemia, humoral immune defect, hypoalphaglobulinemia, immunoglobulin a deficiency, immunoglobulin a1 deficiency, etc

Short Description:Selective deficiency of immunoglobulin A [IgA]
Long Description:Selective deficiency of immunoglobulin A [IgA]

Index to Diseases and Injuries

The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10 code(s). The following references for the code D80.2 are found in the index:


The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Abnormal alpha globulin level
  • Chromosome 22 abnormalities with hypogammaglobulinemia
  • Humoral immune defect
  • Hypoalphaglobulinemia
  • Immunoglobulin A deficiency
  • Immunoglobulin A1 deficiency
  • Immunoglobulin A2 deficiency
  • Immunoglobulin heavy chain deficiency
  • Immunoglobulin heavy chain deficiency
  • Monosomy 22 and absence of immunoglobulin A
  • Selective immunoglobulin A deficiency
  • Selective immunoglobulin M and immunoglobulin A deficiency

Diagnostic Related Groups

The ICD-10 code D80.2 is grouped in the following groups for version MS-DRG V38.0 What are Diagnostic Related Groups?
The Diagnostic Related Groups (DRGs) are a patient classification scheme which provides a means of relating the type of patients a hospital treats. The DRGs divides all possible principal diagnoses into mutually exclusive principal diagnosis areas referred to as Major Diagnostic Categories (MDC).
applicable from 10/01/2020 through 09/30/2021.


Convert D80.2 to ICD-9

  • 279.01 - Selective iga immunodef

Code Classification

  • Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (D50–D89)
    • Certain disorders involving the immune mechanism (D80-D89)
      • Immunodeficiency with predominantly antibody defects (D80)

Code History

  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016
    (First year ICD-10-CM implemented into the HIPAA code set)
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021

Information for Patients

Immune System and Disorders

Your immune system is a complex network of cells, tissues, and organs that work together to defend against germs. It helps your body to recognize these "foreign" invaders. Then its job is to keep them out, or if it can't, to find and destroy them.

If your immune system cannot do its job, the results can be serious. Disorders of the immune system include

  • Allergy and asthma - immune responses to substances that are usually not harmful
  • Immune deficiency diseases - disorders in which the immune system is missing one or more of its parts
  • Autoimmune diseases - diseases causing your immune system to attack your own body's cells and tissues by mistake

NIH: National Institute of Allergy and Infectious Diseases

  • Agammaglobulinemia (Medical Encyclopedia)
  • Aging changes in immunity (Medical Encyclopedia)
  • Chronic granulomatous disease (Medical Encyclopedia)
  • Graft-versus-host disease (Medical Encyclopedia)
  • Histiocytosis (Medical Encyclopedia)
  • Hyperimmunoglobulin E syndrome (Medical Encyclopedia)
  • Immune response (Medical Encyclopedia)
  • Immunodeficiency disorders (Medical Encyclopedia)
  • Selective deficiency of IgA (Medical Encyclopedia)

[Learn More]