2026 ICD-10-CM Diagnosis Code D48.110Desmoid tumor of head and neck

ICD-10-CM Codes›C00–D49›D37-D48›D48

ICD-10-CM D48.110
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

D48.110 is a billable ICD-10-CM diagnosis code for desmoid tumor of head and neck. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 564 through 566. Coders also document this condition as aggressive fibromatosis of head and neck. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Neoplasms of unspecified nature or uncertain behavior.

Code Identity

ICD-10-CM Code
D48.110
Billable Status
Yes — Valid for Submission
Code Describes
Desmoid tumor of head and neck
Short Description
Desmoid tumor of head and neck
Same as the full description in the CMS dataset.
Parent Code
D48.11
Desmoid tumor

Code Classification

ChapterC00–D49Neoplasms
SectionD37-D48Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
CategoryD48Neoplasm of uncertain behavior of other and unspecified sites
This CodeD48.110Desmoid tumor of head and neck

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Aggressive fibromatosis of head and neck
  • Neoplasm of uncertain behavior of soft tissues of neck

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Desmoid(extra-abdominal) (tumor)
      • head and neck

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO072
Neoplasms of unspecified nature or uncertain behavior
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Desmoid tumor

A desmoid tumor is an abnormal growth that arises from connective tissue, which is the tissue that provides strength and flexibility to structures such as bones, ligaments, and muscles. Affected individuals typically develop a single tumor, although some have multiple tumors.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code History & ChangesHistory

Replacement D48.110 replaces the following previously assigned code(s):

  • D48.1 - Neoplasm of uncertain behavior of connctv/soft tiss
FY 2024AddedAdded to the ICD-10-CM code setEffective October 1, 2023.
FY 2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About D48.110Overview

Is D48.110 (Desmoid tumor) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report desmoid tumor of head and neck on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does D48.110 group to?

When desmoid tumor of head and neck is the principal diagnosis on an inpatient stay, it groups to MS-DRG 564, 565, 566, with relative weights from 0.7493 to 1.5436 depending on complications. Higher weights mean higher Medicare reimbursement.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.