2026 ICD-10-CM Diagnosis Code C95.00Acute leukemia of unspecified cell type not having achieved remission
ICD-10-CM Codes›C00–D49›C81-C96›C95
- Billable — Valid for Submission
- Chronic Condition
C95.00 is a billable ICD-10-CM diagnosis code for acute leukemia of unspecified cell type not having achieved remission. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 820 through 822, 834 through 839. Coders also document this condition as acute biphenotypic leukemia. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Leukemia - all other types.
Code Identity
Code Classification
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Acute biphenotypic leukemia
- Acute leukemia
- Acute leukemia of ambiguous lineage
- Acute undifferentiated leukemia
- Mixed phenotype acute leukemia
- Mixed phenotype acute leukemia with myeloid and B-cell lymphoid phenotypes
- Mixed phenotype acute leukemia with T-cell and myeloid lineage
Tabular List NotesGuidance
Coding notes and annotation back-references applicable to this code.
Inclusion Terms
- Acute leukemia of unspecified cell type with failed remission
- Acute leukemia NOS
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Leukemia
Leukemia is a term for cancers of the blood cells. Leukemia starts in blood-forming tissues such as the bone marrow. Your bone marrow makes the cells which will develop into white blood cells, red blood cells, and platelets. Each type of cell has a different job:
The full article covers:
- What is leukemia?
- What are the types of leukemia?
- What causes leukemia?
- Who is at risk for leukemia?
- What are the symptoms of leukemia?
- How is leukemia diagnosed?
- What are the treatments for leukemia?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert C95.00 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About C95.00Overview
Is C95.00 (Acute leukemia of unspecified cell type) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report acute leukemia of unspecified cell type not having achieved remission on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What MS-DRG does C95.00 group to?
When acute leukemia of unspecified cell type not having achieved remission is the principal diagnosis on an inpatient stay, it groups to MS-DRG 820, 821, 822, 834, 835, 836, 837, 838, 839, with relative weights from 1.2040 to 5.8648 depending on complications. Higher weights mean higher Medicare reimbursement.
What is the ICD-9 equivalent of C95.00?
Under the General Equivalence Mappings, acute leukemia of unspecified cell type not having achieved remission converts to ICD-9-CM 208.00 (ac leu un cl wo ach rmsn). The mapping is a direct match.
Footnotes
[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:
- The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
- The condition places limitations on self-care, independent living, and social interactions.
