2026 ICD-10-CM Diagnosis Code C46.4Kaposi's sarcoma of gastrointestinal sites

ICD-10-CM Codes›C00–D49›C45-C49›C46

ICD-10-CM C46.4
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

C46.4 is a billable ICD-10-CM diagnosis code for Kaposi's sarcoma of gastrointestinal sites. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 374 through 376, 974 through 976. Coders also document this condition as kaposi sarcoma of colon. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Sarcoma.

Code Identity

ICD-10-CM Code
C46.4
Billable Status
Yes — Valid for Submission
Code Describes
Kaposi's sarcoma of gastrointestinal sites
Short Description
Kaposi's sarcoma of gastrointestinal sites
Same as the full description in the CMS dataset.
Parent Code
C46
Kaposi's sarcoma

Code Classification

ChapterC00–D49Neoplasms
SectionC45-C49Malignant neoplasms of mesothelial and soft tissue
CategoryC46Kaposi's sarcoma
This CodeC46.4Kaposi's sarcoma of gastrointestinal sites

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Kaposi sarcoma of colon
  • Kaposi sarcoma of rectum
  • Kaposi sarcoma of viscus
  • Kaposi's sarcoma of gastrointestinal tract
  • Neoplasm of blood vessel of pelvis
  • Primary Kaposi sarcoma of gastrointestinal tract

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Kaposi's
      • sarcoma
        • colon
    • Kaposi's
      • sarcoma
        • gastrointestinal organ
    • Kaposi's
      • sarcoma
        • rectum
    • Kaposi's
      • sarcoma
        • stomach
    • Sarcoma(of)
      • Kaposi's
        • colon
    • Sarcoma(of)
      • Kaposi's
        • gastrointestinal organ
    • Sarcoma(of)
      • Kaposi's
        • rectum
    • Sarcoma(of)
      • Kaposi's
        • stomach

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR NEO024
Sarcoma
Default principal diagnosis: inpatient Yes · outpatient Yes

Patient EducationClinical

Kaposi Sarcoma

Kaposi sarcoma, sometimes called KS, is a type of cancer. It causes lesions (abnormal tissue) to grow in different parts of the body, including:

The full article covers:

  • What is Kaposi sarcoma?
  • What causes Kaposi sarcoma and who is more likely to develop it?
  • What are the symptoms of Kaposi sarcoma?
  • How is Kaposi sarcoma diagnosed?
  • What are the treatments for Kaposi sarcoma?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert C46.4 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
176.3 GI sites - kpsi's srcoma
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About C46.4Overview

Is C46.4 (Kaposi's sarcoma) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report Kaposi's sarcoma of gastrointestinal sites on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What MS-DRG does C46.4 group to?

When Kaposi's sarcoma of gastrointestinal sites is the principal diagnosis on an inpatient stay, it groups to MS-DRG 374, 375, 376, 974, 975, 976, with relative weights from 0.8945 to 2.8860 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of C46.4?

Under the General Equivalence Mappings, Kaposi's sarcoma of gastrointestinal sites converts to ICD-9-CM 176.3 (GI sites - kpsi's srcoma). The mapping is a direct match.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.