2026 ICD-10-CM Diagnosis Code Z88.8Allergy status to other drugs, medicaments and biological substances
ICD-10-CM Z88.8
Z88.8 is a billable ICD-10-CM diagnosis code for allergy status to other drugs, medicaments and biological substances. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The code is not accepted as a principal diagnosis by the Medicare Code Editor and exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified status.
Code Identity
ICD-10-CM Code
Z88.8
Billable Status
Yes — Valid for Submission
Code Describes
Allergy status to other drugs, medicaments and biological substances
Short Description
Allergy status to other drug/meds/biol subst
Code Classification
SectionZ77-Z99Persons with potential health hazards related to family and personal history and certain conditions influencing health status
This CodeZ88.8Allergy status to other drugs, medicaments and biological substances
Code EditsBilling
Medicare Code Editor checks that affect claim validity for Z88.8.
There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.
Present on Admission (POA)Billing
Z88.8 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Allergic reaction to galactose-alpha 1,3 galactose
- Allergy to 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitor
- Allergy to 5-hydroxytryptamine-3-receptor antagonist
- Allergy to A series prostaglandin
- Allergy to acarbose
- Allergy to acebutolol
- Allergy to acenocoumarol
- Allergy to acetazolamide
- Allergy to acetohexamide
- Allergy to acetylcholine
- Allergy to acetylcholinesterase inhibitor
- Allergy to acetylcysteine
- Allergy to acipimox
- Allergy to acitretin
- Allergy to acrivastine
- Allergy to activated charcoal
- Allergy to adenosine
- Allergy to adhesive agent
- Allergy to albumin solution
- Allergy to albuterol
- Allergy to alclometasone
- Allergy to alcuronium
- Allergy to aldehyde
- Allergy to aldehyde dehydrogenase inhibitor
- Allergy to aldesleukin
- Allergy to aldosterone receptor antagonist
- Allergy to alfuzosin
- Allergy to alkylating agent
- Allergy to allopurinol
- Allergy to allylestrenol
- Allergy to alpha adrenergic receptor agonist
- Allergy to alpha adrenergic receptor antagonist
- Allergy to alpha-tocopherol
- Allergy to alprazolam
- Allergy to alprostadil
- Allergy to alteplase
- Allergy to aluminum hydroxide
- Allergy to alverine
- Allergy to amfetamine and/or amfetamine derivative
- Allergy to amifostine
- Allergy to amiloride
- Allergy to aminoglutethimide
- Allergy to aminophylline
- Allergy to amiodarone
- Allergy to amitriptyline
- Allergy to amlodipine
- Allergy to amobarbital
- Allergy to amoxapine
- Allergy to amsacrine
- Allergy to anabolic steroid
- Allergy to ancrod
- Allergy to androgen
- Allergy to anistreplase
- Allergy to antazoline
- Allergy to anthralin
- Allergy to antidiuretic hormone
- Allergy to anti-inhibitor coagulant complex
- Allergy to antithrombin III
- Allergy to apomorphine
- Allergy to apraclonidine
- Allergy to aprotinin
- Allergy to ascorbic acid
- Allergy to aspirin
- Allergy to astemizole
- Allergy to atenolol
- Allergy to atorvastatin
- Allergy to atracurium
- Allergy to atropine
- Allergy to auranofin
- Allergy to azatadine
- Allergy to azathioprine
- Allergy to azelaic acid
- Allergy to azelastine
- Allergy to baclofen
- Allergy to bambuterol
- Allergy to bamethan
- Allergy to barbiturate
- Allergy to beclamide
- Allergy to beclomethasone
- Allergy to beef insulin
- Allergy to belladonna alkaloid
- Allergy to bendroflumethiazide
- Allergy to benperidol
- Allergy to benserazide and/or levodopa
- Allergy to bentonite
- Allergy to benzalkonium
- Allergy to benzimidazole
- Allergy to benzodiazepine
- Allergy to benzodiazepine receptor antagonist
- Allergy to benztropine
- Allergy to beractant
- Allergy to beta adrenergic receptor antagonist
- Allergy to beta-1 adrenergic receptor antagonist
- Allergy to beta-2 adrenergic receptor agonist
- Allergy to betahistine
- Allergy to betamethasone
- Allergy to betaxolol
- Allergy to bethanechol
- Allergy to bethanidine
- Allergy to bezafibrate
- Allergy to bicalutamide
- Allergy to biguanide
- Allergy to bile acid
- Allergy to biperiden
- Allergy to bisacodyl
- Allergy to bisoprolol
- Allergy to bisphosphonate
- Allergy to bretylium
- Allergy to bromazepam
- Allergy to bromelains
- Allergy to bromhexine
- Allergy to bromocriptine
- Allergy to brompheniramine
- Allergy to budesonide
- Allergy to bufexamac
- Allergy to buserelin
- Allergy to buspirone
- Allergy to busulfan
- Allergy to butobarbital
- Allergy to butriptyline
- Allergy to butyrophenone derivative
- Allergy to cabergoline
- Allergy to calamine
- Allergy to calcipotriol
- Allergy to calcitonin
- Allergy to calcium regulating hormone
- Allergy to canagliflozin
- Allergy to carbachol
- Allergy to carbamate
- Allergy to carbamazepine
- Allergy to carbaryl
- Allergy to carbenoxolone
- Allergy to carbidopa and/or levodopa
- Allergy to carbimazole
- Allergy to carbocysteine
- Allergy to carbomer-940
- Allergy to carboplatin
- Allergy to carboprost
- Allergy to carboxymethylcellulose
- Allergy to carisoprodol
- Allergy to carmustine
- Allergy to carteolol
- Allergy to carvedilol
- Allergy to cascara
- Allergy to castor oil
- Allergy to cattle protein
- Allergy to celiprolol
- Allergy to cellulose and/or cellulose derivative
- Allergy to cerivastatin
- Allergy to cetirizine
- Allergy to cetuximab due to alpha-gal syndrome
- Allergy to chenodeoxycholic acid
- Allergy to chenodeoxycholic acid and/or ursodeoxycholic acid
- Allergy to chloral derivative
- Allergy to chloral hydrate
- Allergy to chlorambucil
- Allergy to chlordiazepoxide
- Allergy to chlormethiazole
- Allergy to chlormezanone
- Allergy to chlorothiazide
- Allergy to chlorpheniramine
- Allergy to chlorpromazine
- Allergy to chlorpropamide
- Allergy to chlorprothixene
- Allergy to cholestyramine
- Allergy to chymotrypsin
- Allergy to cimetidine
- Allergy to cinnarizine
- Allergy to ciprofibrate
- Allergy to cisapride
- Allergy to cisatracurium
- Allergy to cisplatin
- Allergy to citalopram
- Allergy to clemastine
- Allergy to clobazam
- Allergy to clobetasol
- Allergy to clobetasone
- Allergy to clodronic acid
- Allergy to clofibrate
- Allergy to clomiphene
- Allergy to clomipramine
- Allergy to clonazepam
- Allergy to clonidine
- Allergy to clorazepate
- Allergy to Clostridium botulinum toxin
- Allergy to clozapine
- Allergy to coagulation factor V
- Allergy to coagulation factor VII
- Allergy to coagulation factor VIIa
- Allergy to coagulation factor XI
- Allergy to coagulation protein
- Allergy to coal tar
- Allergy to colchicine
- Allergy to Colchicum alkaloid
- Allergy to colestipol
- Allergy to colfosceril
- Allergy to collagen
- Allergy to collodion
- Allergy to conjugated estrogen
- Allergy to contrast media
- Allergy to corticosteroid and/or corticosteroid derivative
- Allergy to corticotrophic hormone
- Allergy to cortisone
- Allergy to crisantaspase
- Allergy to cromolyn
- Allergy to crotamiton
- Allergy to cyanocobalamin
- Allergy to cyclandelate
- Allergy to cyclizine
- Allergy to cyclobarbital
- Allergy to cyclofenil
- Allergy to cyclopenthiazide
- Allergy to cyclopentolate
- Allergy to cyclophosphamide
- Allergy to cyclosporine
- Allergy to cyproheptadine
- Allergy to cyproterone
- Allergy to cyproterone and/or ethinylestradiol
- Allergy to cytarabine
- Allergy to dacarbazine
- Allergy to dalteparin
- Allergy to danaparoid
- Allergy to danazol
- Allergy to danthron
- Allergy to dantrolene
- Allergy to dapagliflozin
- Allergy to debrisoquine
- Allergy to deferoxamine
- Allergy to dehydrocholic acid
- Allergy to demecarium
- Allergy to denosumab
- Allergy to deoxyribonuclease
- Allergy to desipramine
- Allergy to desmopressin
- Allergy to desonide
- Allergy to desoximetasone
- Allergy to dexamethasone
- Allergy to dexfenfluramine
- Allergy to dextroamphetamine
- Allergy to dextromethorphan
- Allergy to dextrothyroxine
- Allergy to dialysis fluid
- Allergy to diazepam
- Allergy to diazoxide
- Allergy to dibromopropamidine
- Allergy to dichloralphenazone
- Allergy to dicyclomine
- Allergy to dienestrol
- Allergy to diethylpropion
- Allergy to diethylstilbestrol
- Allergy to diflucortolone
- Allergy to Digitalis glycoside
- Allergy to digitoxin
- Allergy to digoxin
- Allergy to digoxin immune fab
- Allergy to dihydroergocristine and/or dihydroergocornine and/or dihydroergocryptine
- Allergy to dihydroergotamine
- Allergy to diltiazem
- Allergy to dimenhydrinate
- Allergy to dimercaprol
- Allergy to dimethindene
- Allergy to dimethyl sulfoxide
- Allergy to dimethyl-ether propane
- Allergy to dinoprost
- Allergy to dinoprostone
- Allergy to diphenhydramine
- Allergy to diphenylbutylpiperidine
- Allergy to diphenylpyraline
- Allergy to diphtheria antitoxin
- Allergy to dipivefrin
- Allergy to dipyridamole
- Allergy to disopyramide
- Allergy to distigmine
- Allergy to disulfiram
- Allergy to dobutamine
- Allergy to docusate
- Allergy to domperidone
- Allergy to dopamine
- Allergy to dopexamine
- Allergy to dornase alfa
- Allergy to dothiepin
- Allergy to doxacurium
- Allergy to doxapram
- Allergy to doxazosin
- Allergy to doxepin
- Allergy to droperidol
- Allergy to drostanolone
- Allergy to dydrogesterone
- Allergy to E series prostaglandin
- Allergy to echothiophate
- Allergy to edetate
- Allergy to edrophonium
- Allergy to emepronium
- Allergy to empagliflozin
- Allergy to enbucrilate
- Allergy to enoxaparin
- Allergy to enoximone
- Allergy to ephedrine
- Allergy to eplerenone
- Allergy to epoetin alfa
- Allergy to epoetin beta
- Allergy to epoprostenol
- Allergy to ergoline derivative
- Allergy to ergometrine and/or oxytocin
- Allergy to ergonovine
- Allergy to ergot alkaloid
- Allergy to ertugliflozin
- Allergy to erythropoietin receptor agonist
- Allergy to esmolol
- Allergy to estradiol
- Allergy to estramustine
- Allergy to estriol
- Allergy to estrogen
- Allergy to estrogen receptor antagonist
- Allergy to estrone
- Allergy to etamsylate
- Allergy to ethacrynic acid
- Allergy to ethamivan
- Allergy to ethanol
- Allergy to ethanolamine
- Allergy to ethinyl estradiol
- Allergy to ethoglucid
- Allergy to ethosuximide
- Allergy to ethynodiol
- Allergy to etidronic acid
- Allergy to etoposide
- Allergy to etretinate
- Allergy to F series prostaglandin
- Allergy to famotidine
- Allergy to felodipine
- Allergy to fenfluramine
- Allergy to fenofibrate
- Allergy to fenoprofen
- Allergy to fenoterol
- Allergy to ferrous fumarate
- Allergy to ferrous gluconate
- Allergy to ferrous glycine sulfate
- Allergy to ferrous phosphate
- Allergy to ferrous salt
- Allergy to ferrous succinate
- Allergy to ferrous sulfate
- Allergy to fibric acid and/or fibric acid derivative
- Allergy to filgrastim
- Allergy to finasteride
- Allergy to flavoxate
- Allergy to flecainide
- Allergy to flosequinan
- Allergy to fluclorolone
- Allergy to fludarabine
- Allergy to fludrocortisone
- Allergy to flumazenil
- Allergy to flunisolide
- Allergy to flunitrazepam
- Allergy to fluocinolone
- Allergy to fluocinonide
- Allergy to fluocortolone
- Allergy to fluoride
- Allergy to fluorometholone
- Allergy to fluorouracil
- Allergy to fluoxetine
- Allergy to flupentixol
- Allergy to fluphenazine
- Allergy to flurandrenolide
- Allergy to flurazepam
- Allergy to fluspirilene
- Allergy to flutamide
- Allergy to fluticasone
- Allergy to fluvastatin
- Allergy to fluvoxamine
- Allergy to folic acid
- Allergy to folic acid and/or iron compound
- Allergy to folinic acid
- Allergy to formestane
- Allergy to Fuller's earth
- Allergy to fungus
- Allergy to gabapentin
- Allergy to galactose-alpha-1,3 galactose
- Allergy to gallamine
- Allergy to gamolenic acid
- Allergy to gemeprost
- Allergy to gemfibrozil
- Allergy to gestonorone
- Allergy to gestrinone
- Allergy to glibornuride
- Allergy to gliclazide
- Allergy to glipizide
- Allergy to gliquidone
- Allergy to glucagon
- Allergy to glyburide
- Allergy to glycerin
- Allergy to glycine
- Allergy to glycopyrronium
- Allergy to glymidine
- Allergy to gold
- Allergy to gold sodium thiomalate
- Allergy to gonad regulating hormone agent
- Allergy to gonadorelin
- Allergy to gonadotropin
- Allergy to goserelin
- Allergy to guanethidine
- Allergy to guar gum
- Allergy to H+/K+-exchanging ATPase inhibitor
- Allergy to halcinonide
- Allergy to haloperidol
- Allergy to heparin
- Allergy to heparinoid
- Allergy to Hepatitis b surface antigen immunoglobulin
- Allergy to histamine H1 receptor antagonist
- Allergy to histamine H2 receptor antagonist
- Allergy to homatropine
- Allergy to human anti-D immunoglobulin
- Allergy to human immunoglobulin
- Allergy to human insulin
- Allergy to hyaluronic acid
- Allergy to hyaluronidase
- Allergy to hydralazine
- Allergy to hydrochlorothiazide
- Allergy to hydrocortisone
- Allergy to hydroflumethiazide
- Allergy to hydroxocobalamin
- Allergy to hydroxyethylcellulose
- Allergy to hydroxyprogesterone
- Allergy to hydroxyurea
- Allergy to hydroxyzine
- Allergy to hypothalamic hormone
- Allergy to hypromellose
- Allergy to I series prostaglandin
- Allergy to ifosfamide
- Allergy to imipramine
- Allergy to immunoglobulin
- Allergy to indanedione
- Allergy to indoramin
- Allergy to inositol
- Allergy to insulin
- Allergy to iodine compound
- Allergy to ipecacuanha
- Allergy to ipratropium
- Allergy to iprindole
- Allergy to iproniazid
- Allergy to iron compound
- Allergy to iron sorbitol
- Allergy to isoaminile
- Allergy to isocarboxazid
- Allergy to isoetharine
- Allergy to isophane insulin
- Allergy to isoproterenol
- Allergy to isosorbide
- Allergy to isotretinoin
- Allergy to isoxsuprine
- Allergy to isradipine
- Allergy to kaolin
- Allergy to ketazolam
- Allergy to ketotifen
- Allergy to labetalol
- Allergy to lachesine
- Allergy to lacidipine
- Allergy to lactulose
- Allergy to lamotrigine
- Allergy to lanatoside C
- Allergy to lansoprazole
- Allergy to lenograstim
- Allergy to leuprorelin
- Allergy to levamisole
- Allergy to levobunolol
- Allergy to levocarnitine
- Allergy to levodopa
- Allergy to levonorgestrel
- Allergy to licorice
- Allergy to lidoflazine
- Allergy to lindane
- Allergy to liothyronine
- Allergy to lisuride
- Allergy to lithium carbonate
- Allergy to lithium citrate
- Allergy to lithium compound
- Allergy to lodoxamide
- Allergy to lofepramine
- Allergy to lofexidine
- Allergy to lomustine
- Allergy to loperamide
- Allergy to loprazolam
- Allergy to loratadine
- Allergy to lorazepam
- Allergy to lormetazepam
- Allergy to lovastatin
- Allergy to loxapine
- Allergy to magnesium sulfate
- Allergy to magnesium trisilicate
- Allergy to malathion
- Allergy to mannitol
- Allergy to maprotiline
- Allergy to mazindol
- Allergy to mebeverine
- Allergy to mebhydrolin
- Allergy to mechlorethamine
- Allergy to meclizine
- Allergy to medazepam
- Allergy to medigoxin
- Allergy to medroxyprogesterone
- Allergy to megestrol
- Allergy to meglitinide
- Allergy to melphalan
- Allergy to mepenzolate
- Allergy to mephobarbital
- Allergy to meprobamate
- Allergy to mequitazine
- Allergy to mercaptopurine
- Allergy to mercuric oxide
- Allergy to mersalyl
- Allergy to mesalamine
- Allergy to mesna
- Allergy to mesterolone
- Allergy to mestranol
- Allergy to metaproterenol
- Allergy to metaraminol
- Allergy to metformin
- Allergy to methacholine
- Allergy to methixene
- Allergy to methocarbamol
- Allergy to methotrexate
- Allergy to methoxamine
- Allergy to methyclothiazide
- Allergy to methylcysteine
- Allergy to methyldopa
- Allergy to methylphenidate
- Allergy to methylprednisolone
- Allergy to methyltestosterone
- Allergy to methyprylon
- Allergy to metipranolol
- Allergy to metoclopramide
- Allergy to metoprolol
- Allergy to metyrosine
- Allergy to mexiletine
- Allergy to mianserin
- Allergy to mifepristone
- Allergy to milrinone
- Allergy to minoxidil
- Allergy to misoprostol
- Allergy to mitobronitol
- Allergy to mivacurium
- Allergy to moclobemide
- Allergy to mold
- Allergy to molgramostim
- Allergy to mometasone
- Allergy to monoamine oxidase inhibitor
- Allergy to moricizine
- Allergy to moxisylyte
- Allergy to nabilone
- Allergy to nadolol
- Allergy to nafarelin
- Allergy to nafronyl
- Allergy to naloxone
- Allergy to naltrexone
- Allergy to nandrolone
- Allergy to naphazoline
- Allergy to nebivolol
- Allergy to nedocromil
- Allergy to nefazodone
- Allergy to neostigmine
- Allergy to niacin
- Allergy to nicardipine
- Allergy to nicofuranose
- Allergy to nicorandil
- Allergy to nicotine
- Allergy to nicotinyl alcohol
- Allergy to nifedipine
- Allergy to nikethamide
- Allergy to nimodipine
- Allergy to nitrazepam
- Allergy to nitrogen mustard derivative
- Allergy to nitroglycerin
- Allergy to nitroprusside
- Allergy to nitrosurea
- Allergy to nizatidine
- Allergy to nondepolarizing agent
- Allergy to nonionic surfactant
- Allergy to nonoxynol
- Allergy to norepinephrine
- Allergy to norethindrone
- Allergy to nortriptyline
- Allergy to octoxinol
- Allergy to octreotide
- Allergy to olsalazine
- Allergy to omeprazole
- Allergy to opiate agonist
- Allergy to opioid receptor antagonist
- Allergy to opium alkaloid
- Allergy to organic phosphorus compound
- Allergy to orphenadrine
- Allergy to ouabain
- Allergy to oxatomide
- Allergy to oxazepam
- Allergy to oxedrine
- Allergy to oxitropium
- Allergy to oxprenolol
- Allergy to oxybutynin
- Allergy to oxymetazoline
- Allergy to oxymetholone
- Allergy to oxypertine
- Allergy to oxytocin
- Allergy to paclitaxel
- Allergy to pamidronic acid
- Allergy to pancreatin
- Allergy to pancuronium
- Allergy to pantoprazole
- Allergy to papaverine
- Allergy to paraldehyde
- Allergy to paroxetine
- Allergy to pemoline
- Allergy to penbutolol
- Allergy to penicillamine
- Allergy to pentaerythritol tetranitrate
- Allergy to pentostatin
- Allergy to pentoxifylline
- Allergy to peppermint oil
- Allergy to perfluorochemical
- Allergy to pergolide
- Allergy to periciazine
- Allergy to permanganic acid
- Allergy to permethrin
- Allergy to perphenazine
- Allergy to phenelzine
- Allergy to phenindamine
- Allergy to phenindione
- Allergy to pheniramine
- Allergy to phenobarbital
- Allergy to phenothiazine
- Allergy to phenothiazine derivative
- Allergy to phenothrin
- Allergy to phenoxybenzamine
- Allergy to phentermine
- Allergy to phentolamine
- Allergy to phenylephrine
- Allergy to phenylpropanolamine
- Allergy to phenytoin
- Allergy to phosphodiesterase 5 inhibitor
- Allergy to phosphodiesterase inhibitor
- Allergy to phospholipid
- Allergy to physostigmine
- Allergy to pilocarpine
- Allergy to pimozide
- Allergy to pindolol
- Allergy to pipenzolate
- Allergy to piperidolate
- Allergy to pipothiazine
- Allergy to piracetam
- Allergy to pirbuterol
- Allergy to pirenzepine
- Allergy to piretanide
- Allergy to pitavastatin
- Allergy to pituitary hormone
- Allergy to podophyllotoxin
- Allergy to Podophyllum resin
- Allergy to poldine
- Allergy to polyestradiol
- Allergy to polysaccharide-iron complex
- Allergy to polystyrene sulfonate
- Allergy to polythiazide
- Allergy to polyvinyl alcohol
- Allergy to porcine calcitonin
- Allergy to pork insulin
- Allergy to potassium canrenoate
- Allergy to practolol
- Allergy to pralidoxime
- Allergy to pravastatin
- Allergy to prazepam
- Allergy to prazosin
- Allergy to prednisolone
- Allergy to prednisone
- Allergy to prenylamine
- Allergy to primidone
- Allergy to probucol
- Allergy to procainamide
- Allergy to procarbazine
- Allergy to prochlorperazine
- Allergy to procyclidine
- Allergy to progestational hormone
- Allergy to progesterone
- Allergy to prolintane
- Allergy to promazine
- Allergy to promestriene
- Allergy to promethazine
- Allergy to propafenone
- Allergy to propamidine
- Allergy to propantheline
- Allergy to propranolol
- Allergy to propylthiouracil
- Allergy to prostaglandin
- Allergy to protamine
- Allergy to protamine zinc insulin
- Allergy to protirelin
- Allergy to protriptyline
- Allergy to pseudoephedrine
- Allergy to pumactant
- Allergy to pyrethroid
- Allergy to pyridostigmine
- Allergy to pyridoxine
- Allergy to pyrilamine
- Allergy to quaternary ammonium surfactant
- Allergy to quinagolide
- Allergy to quinestradol
- Allergy to quinestrol
- Allergy to quinidine
- Allergy to radiopharmaceutical
- Allergy to raloxifene
- Allergy to ranitidine
- Allergy to rapacuronium
- Allergy to rauwolfia alkaloid
- Allergy to razoxane
- Allergy to remoxipride
- Allergy to reproterol
- Allergy to reteplase
- Allergy to retinoid
- Allergy to rimiterol
- Allergy to risperidone
- Allergy to ritodrine
- Allergy to rocuronium
- Allergy to rosuvastatin
- Allergy to rubber
- Allergy to salicylate
- Allergy to salicylic acid
- Allergy to salmeterol
- Allergy to scopolamine
- Allergy to secobarbital
- Allergy to selective serotonin re-uptake inhibitor
- Allergy to selegiline
- Allergy to senna
- Allergy to sertraline
- Allergy to simvastatin
- Allergy to sodium iron edetate
- Allergy to sodium nitrite
- Allergy to sodium picosulfate
- Allergy to sodium polystyrene sulfonate
- Allergy to sodium sulfate
- Allergy to somatropin hormone
- Allergy to sotalol
- Allergy to spironolactone
- Allergy to stanozolol
- Allergy to streptokinase
- Allergy to streptokinase streptodornase
- Allergy to substance with sodium glucose cotransporter subtype 2 inhibitor mechanism of action
- Allergy to substance with triazole structure
- Allergy to succinylcholine
- Allergy to sucralfate
- Allergy to sulfasalazine
- Allergy to sulfinpyrazone
- Allergy to sulfonylurea
- Allergy to sulpiride
- Allergy to surgical tissue adhesive
- Allergy to tamoxifen
- Allergy to temazepam
- Allergy to tenecteplase
- Allergy to terazosin
- Allergy to terbutaline
- Allergy to terfenadine
- Allergy to teriparatide
- Allergy to terlipressin
- Allergy to terodiline
- Allergy to terpene
- Allergy to testosterone
- Allergy to tetrabenazine
- Allergy to tetracosactrin
- Allergy to theophylline
- Allergy to thiamine
- Allergy to thiazide
- Allergy to thiazolidinedione
- Allergy to thiethylperazine
- Allergy to thioguanine
- Allergy to thioridazine
- Allergy to thiotepa
- Allergy to thiouracil
- Allergy to thiourea
- Allergy to thioxanthene
- Allergy to thromboplastin
- Allergy to thymol
- Allergy to thyroid hormone
- Allergy to thyrotrophin
- Allergy to thyrotropin releasing factor
- Allergy to thyroxine
- Allergy to tibolone
- Allergy to timolol
- Allergy to tinzaparin
- Allergy to tocainide
- Allergy to tolazamide
- Allergy to tolbutamide
- Allergy to torsemide
- Allergy to tranexamic acid
- Allergy to tranylcypromine
- Allergy to trazodone
- Allergy to treosulfan
- Allergy to tretinoin
- Allergy to triamcinolone
- Allergy to triamterene
- Allergy to triazene
- Allergy to triazolam
- Allergy to trichloroethylene
- Allergy to triclofos
- Allergy to trientine
- Allergy to trifluoperazine
- Allergy to trifluperidol
- Allergy to trihexyphenidyl
- Allergy to trilostane
- Allergy to trimeprazine
- Allergy to trimethaphan
- Allergy to trimipramine
- Allergy to triphenylmethane triisocyanate
- Allergy to tripotassium dicitratobismuthate
- Allergy to triprolidine
- Allergy to triptorelin
- Allergy to tropicamide
- Allergy to tuberculin purified protein derivative
- Allergy to tubocurarine
- Allergy to tulobuterol
- Allergy to tyloxapol
- Allergy to urea
- Allergy to urokinase
- Allergy to ursodeoxycholic acid
- Allergy to valproic acid
- Allergy to vecuronium
- Allergy to venlafaxine
- Allergy to verapamil
- Allergy to vigabatrin
- Allergy to viloxazine
- Allergy to vinblastine
- Allergy to Vinca alkaloid
- Allergy to vincristine
- Allergy to vindesine
- Allergy to vitamin A
- Allergy to vitamin B12 and/or vitamin B12 derivative
- Allergy to vitamin D and/or vitamin D derivative
- Allergy to vitamin K and/or vitamin K derivative
- Allergy to warfarin
- Allergy to xamoterol
- Allergy to xanthine
- Allergy to xanthine oxidase inhibitor
- Allergy to xylometazoline
- Allergy to zinc and/or zinc compound
- Allergy to zinc insulin
- Allergy to zoledronic acid
- Allergy to zolpidem
- Allergy to zopiclone
- Allergy to zuclopenthixol
- Decreased drug tolerance
- Drug tolerance
- H/O: angiotensin converting enzyme inhibitor pseudoallergy
- History of intravenous iron allergy
- Hypersensitivity to atenolol
- Hypersensitivity to hydrocortisone
- Hypersensitivity to polyethylene glycol
- Hypersensitivity to polysorbate-80
- Hypersensitivity to succinylcholine
- Propensity to adverse reaction to potassium
- Warfarin sensitivity
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
- History
- personal (of) - See Also: History, family (of);
- allergy (to) - Z88.9
- drugs, medicaments and biological substances - Z88.9
- specified NEC - Z88.8
- specified NEC - Z88.8
External Cause of Injuries IndexGuidance
References for this code in the External Cause of Injuries Index.
- History
- personal (of)
- allergy (to)
- drugs, medicaments and biological substances
- specified NEC
- History
- personal (of)
- allergy (to)
- medicinal agents
- specified NEC
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
CCSR FAC025
Other specified status
Default principal diagnosis: inpatient No · outpatient Yes
Clinical InformationClinical
Drug Tolerance
progressive diminution of the susceptibility of a human or animal to the effects of a drug, resulting from its continued administration. it should be differentiated from drug resistance wherein an organism, disease, or tissue fails to respond to the intended effectiveness of a chemical or drug. it should also be differentiated from maximum tolerated dose and no-observed-adverse-effect level.
Patient EducationClinical
Drug Reactions
Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.
The full article covers:
- What is a drug interaction?
- What are side effects?
- What are drug allergies?
- How can I stay safe when taking medicines?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert Z88.8 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2020No changes
FY 2021RevisedCode revised
FY 2022–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.
Questions About Z88.8Overview
Is Z88.8 a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report allergy status to other drugs, medicaments and biological substances on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
Can Z88.8 be a principal diagnosis?
No. The Medicare Code Editor rejects this code as a principal diagnosis because allergy status to other drugs, medicaments and biological substances describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.
Is Z88.8 exempt from POA reporting?
Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for allergy status to other drugs, medicaments and biological substances on inpatient claims.
What is the ICD-9 equivalent of Z88.8?
Under the General Equivalence Mappings, allergy status to other drugs, medicaments and biological substances converts to ICD-9-CM V14.8 (hx-drug allergy NEC). The mapping is a direct match.
