2026 ICD-10-CM Diagnosis Code Z88Allergy status to drugs, medicaments and biological substances

ICD-10-CM CodesZ00–Z99Z77-Z99Z88

ICD-10-CM Z88
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

Z88 is a non-billable ICD-10-CM category code for allergy status to drugs, medicaments and biological substances, so it cannot be submitted on claims. Use a more specific code from this category instead, such as Z88.0, Z88.1, Z88.2, and Z88.3.

Code Identity

ICD-10-CM Code
Z88
Billable Status
No — Non-Billable Category
Code Describes
Allergy status to drugs, medicaments and biological substances
Chapter
Z77-Z99
Persons with potential health hazards related to family and personal history and certain conditions influencing health status

Code Classification

ChapterZ00–Z99Factors influencing health status and contact with health services
SectionZ77-Z99Persons with potential health hazards related to family and personal history and certain conditions influencing health status
CategoryZ88Allergy status to drugs, medicaments and biological substances
This CodeZ88Allergy status to drugs, medicaments and biological substances

Specific Coding for Allergy status to drug/meds/biol substOverview

Non-specific codes like Z88 require more characters. Use one of these billable codes instead:

  • Use Z88.0 for Allergy status to penicillin

  • Use Z88.1 for Allergy status to other antibiotic agents

  • Use Z88.2 for Allergy status to sulfonamides

  • Use Z88.3 for Allergy status to other anti-infective agents

  • Use Z88.4 for Allergy status to anesthetic agent

  • Use Z88.5 for Allergy status to narcotic agent

  • Use Z88.6 for Allergy status to analgesic agent

  • Use Z88.7 for Allergy status to serum and vaccine

  • Use Z88.8 for Allergy status to other drugs, medicaments and biological substances

  • Use Z88.9 for Allergy status to unspecified drugs, medicaments and biological substances

Tabular List NotesGuidance

Coding notes and annotation back-references applicable to this code.

Type 2 Excludes

  • Allergy status, other than to drugs and biological substances Z91.0

Patient EducationClinical

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Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About Z88Overview

Is Z88 a billable code?

No. This is a category header that groups the codes for allergy status to drugs, medicaments and biological substances, and headers cannot be submitted on claims. Claims for allergy status to drugs, medicaments and biological substances need a more specific code from this category, such as Z88.0, Z88.1, and Z88.2.