2024 ICD-10-CM Diagnosis Code Z88.3

Allergy status to other anti-infective agents

ICD-10-CM Code:
Short Description:
Allergy status to other anti-infective agents
Is Billable?
Yes - Valid for Submission
Code Navigator:

Code Classification

  • Factors influencing health status and contact with health services
    • Persons with potential health hazards related to family and personal history and certain conditions influencing health status
      • Allergy status to drug/meds/biol subst

Z88.3 is a billable diagnosis code used to specify a medical diagnosis of allergy status to other anti-infective agents. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024. The code is exempt from present on admission (POA) reporting for inpatient admissions to general acute care hospitals.

This code describes a circumstance which influences the patient's health status but not a current illness or injury. The code is unacceptable as a principal diagnosis.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Allergy to abacavir
  • Allergy to acetic acid
  • Allergy to acridine derivative azo
  • Allergy to acyclovir
  • Allergy to adhesive agent
  • Allergy to albendazole
  • Allergy to aldehyde
  • Allergy to aldehyde
  • Allergy to aldehyde
  • Allergy to amantadine
  • Allergy to aminoquinoline
  • Allergy to amodiaquine
  • Allergy to amorolfine
  • Allergy to amphotericin
  • Allergy to atovaquone
  • Allergy to azole
  • Allergy to balsam of Peru
  • Allergy to benzimidazole
  • Allergy to benzoyl peroxide
  • Allergy to benzyl benzoate
  • Allergy to bephenium
  • Allergy to biguanide
  • Allergy to biguanide
  • Allergy to bismuth subnitrate and/or iodoform
  • Allergy to borate
  • Allergy to boric acid
  • Allergy to brilliant green
  • Allergy to carbamate
  • Allergy to cetrimide
  • Allergy to cetylpyridinium
  • Allergy to chlorhexidine
  • Allergy to chlorhexidine and/or neomycin
  • Allergy to chlorhexidine and/or neomycin
  • Allergy to chlorinated phenol
  • Allergy to chlorinated phenol
  • Allergy to chloroquine
  • Allergy to chloroxylenol
  • Allergy to clioquinol
  • Allergy to clotrimazole
  • Allergy to dapsone
  • Allergy to darunavir
  • Allergy to dequalinium
  • Allergy to diamidine
  • Allergy to dichloroacetamide
  • Allergy to didanosine
  • Allergy to diethylcarbamazine
  • Allergy to diloxanide
  • Allergy to domiphen
  • Allergy to econazole
  • Allergy to ethanol
  • Allergy to famciclovir
  • Allergy to fenticonazole
  • Allergy to fluconazole
  • Allergy to flucytosine
  • Allergy to fluoroquinolone
  • Allergy to formaldehyde
  • Allergy to foscarnet
  • Allergy to ganciclovir
  • Allergy to gentian violet
  • Allergy to glutaraldehyde
  • Allergy to griseofulvin
  • Allergy to halofantrine
  • Allergy to hexachlorophene
  • Allergy to hexetidine
  • Allergy to hydrargaphen
  • Allergy to hydrogen peroxide
  • Allergy to hydroxychloroquine
  • Allergy to ichthammol
  • Allergy to idoxuridine
  • Allergy to imidazole
  • Allergy to industrial methylated spirit
  • Allergy to inosine pranobex
  • Allergy to interferon
  • Allergy to interferon alfa-2a
  • Allergy to interferon alfa-2b
  • Allergy to interferon alfa-n1
  • Allergy to interferon gamma-1b
  • Allergy to iodine compound
  • Allergy to iodine compound
  • Allergy to iodophore
  • Allergy to isoconazole
  • Allergy to itraconazole
  • Allergy to ketoconazole
  • Allergy to macrolide
  • Allergy to mebendazole
  • Allergy to mefloquine
  • Allergy to metronidazole
  • Allergy to miconazole
  • Allergy to monosulfiram
  • Allergy to nalidixic acid
  • Allergy to natamycin
  • Allergy to nevirapine
  • Allergy to niclosamide
  • Allergy to nimorazole
  • Allergy to nitrofurantoin
  • Allergy to nitroimidazole
  • Allergy to nitrophenol
  • Allergy to noxythiolin
  • Allergy to nystatin
  • Allergy to organic phosphorus compound
  • Allergy to oxyquinoline
  • Allergy to pentamidine
  • Allergy to phenol
  • Allergy to piperazine
  • Allergy to polynoxylin
  • Allergy to povidone iodine
  • Allergy to primaquine
  • Allergy to proguanil
  • Allergy to protease inhibitor
  • Allergy to pyrantel
  • Allergy to pyrimethamine
  • Allergy to quaternary ammonium surfactant
  • Allergy to quaternary pyridinium surfactant
  • Allergy to quaternary quinolinium surfactant
  • Allergy to quinacrine
  • Allergy to quinine
  • Allergy to reverse transcriptase inhibitor
  • Allergy to ribavirin
  • Allergy to silver nitrate
  • Allergy to sodium perborate
  • Allergy to sodium stibogluconate
  • Allergy to substance with triazole structure
  • Allergy to sulconazole
  • Allergy to sulfamethoxazole and/or trimethoprim
  • Allergy to terbinafine
  • Allergy to thiabendazole
  • Allergy to thimerosal
  • Allergy to tinidazole
  • Allergy to tioconazole
  • Allergy to tolnaftate
  • Allergy to triazole
  • Allergy to triclosan
  • Allergy to trifluridine
  • Allergy to trimethoprim
  • Allergy to undecenoate
  • Allergy to valacyclovir
  • Allergy to vidarabine
  • Allergy to zalcitabine
  • Allergy to zidovudine
  • Hypersensitivity to abacavir

Clinical Classification

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Code Edits

The Medicare Code Editor (MCE) detects and reports errors in the coding of claims data. The following ICD-10-CM Code Edits are applicable to this code:

  • Unacceptable principal diagnosis - There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Present on Admission (POA)

Z88.3 is exempt from POA reporting - The Present on Admission (POA) indicator is used for diagnosis codes included in claims involving inpatient admissions to general acute care hospitals. POA indicators must be reported to CMS on each claim to facilitate the grouping of diagnoses codes into the proper Diagnostic Related Groups (DRG). CMS publishes a listing of specific diagnosis codes that are exempt from the POA reporting requirement. Review other POA exempt codes here.

CMS POA Indicator Options and Definitions

POA IndicatorReason for CodeCMS will pay the CC/MCC DRG?
YDiagnosis was present at time of inpatient admission.YES
NDiagnosis was not present at time of inpatient admission.NO
UDocumentation insufficient to determine if the condition was present at the time of inpatient admission.NO
WClinically undetermined - unable to clinically determine whether the condition was present at the time of inpatient admission.YES
1Unreported/Not used - Exempt from POA reporting. NO

Convert Z88.3 to ICD-9-CM

  • ICD-9-CM Code: V14.3 - Hx-anti-infect allergy

Patient Education

Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

What is a drug interaction?

A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as gingko and blood thinners
  • Drugs and medical conditions, such as aspirin and peptic ulcers

Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.

What are side effects?

Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.

What are drug allergies?

Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.

How can I stay safe when taking medicines?

When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.

[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - Code Updated, effective from 10/1/2020 through 9/30/2021
    • New Description: Allergy status to other anti-infective agents
    • Previous Description: Allergy status to other anti-infective agents
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.