2026 ICD-10-CM Diagnosis Code Z80.8Family history of malignant neoplasm of other organs or systems
Z80.8 is a billable ICD-10-CM diagnosis code for family history of malignant neoplasm of other organs or systems. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The code is not accepted as a principal diagnosis by the Medicare Code Editor and exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Family history of disease.
Code Identity
Code Classification
Code EditsBilling
Medicare Code Editor checks that affect claim validity for Z80.8.
Present on Admission (POA)Billing
Z80.8 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Family history of basal cell carcinoma of skin
- Family history of glioblastoma multiforme
- Family history of malignant epithelial neoplasm
- Family history of malignant melanoma
- Family history of malignant melanoma in first degree relative
- Family history of malignant neoplasm of bone
- Family history of malignant neoplasm of brain
- Family history of malignant neoplasm of eye proper
- Family history of malignant neoplasm of oral cavity
- Family history of malignant neoplasm of pharynx
- Family history of malignant neoplasm of skin
- Family history of malignant neoplasm of skin in first degree relative
- Family history of malignant neoplasm of thyroid
- Family history of malignant tumor of hypopharynx
- Family history of medullary thyroid carcinoma
- Family history of Muir-Torré syndrome
- Family history of neoplasm of brain
- Family history of neoplasm of central nervous system
- Family history of neoplasm of skin
- Family history of neoplasm of upper aerodigestive tract
- Family history of neuroblastoma
- Family history of non-glaucomatous eye disorder
- Family history of papillary thyroid carcinoma
- Family history of pheochromocytoma
- Family history of sebaceous carcinoma
- Family history of squamous cell carcinoma of skin
- FH: Thyroid disorder
Tabular List NotesGuidance
Coding notes and annotation back-references applicable to this code.
Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
Index to Diseases and InjuriesGuidance
Alphabetical index entries that point to this code.
- History
- family (of) - See Also: History, personal (of);
- malignant neoplasm (of) NOS - Z80.9
- specified site NEC - Z80.8
External Cause of Injuries IndexGuidance
References for this code in the External Cause of Injuries Index.
- History
- family (of)
- malignant neoplasm (of) NOS
- specified site NEC
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Patient EducationClinical
Cancer
Cancer is not just one disease but many diseases. Cancer begins in your cells, which are the building blocks of your body. Usually, your body forms new cells as needed, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should.
The full article covers:
- What is cancer?
- What are the types of cancer?
- How does cancer develop?
- What are the symptoms of cancer?
- How is cancer diagnosed?
- What are the treatments for cancer?
- Can cancer be prevented?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert Z80.8 to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About Z80.8Overview
Is Z80.8 (Family history of primary malignant neoplasm) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report family history of malignant neoplasm of other organs or systems on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
Can Z80.8 be a principal diagnosis?
No. The Medicare Code Editor rejects this code as a principal diagnosis because family history of malignant neoplasm of other organs or systems describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.
Is Z80.8 exempt from POA reporting?
Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for family history of malignant neoplasm of other organs or systems on inpatient claims.
What is the ICD-9 equivalent of Z80.8?
Under the General Equivalence Mappings, family history of malignant neoplasm of other organs or systems converts to ICD-9-CM V16.8 (family hx-malignancy NEC). The mapping is a direct match.
