2027 ICD-10-CM Diagnosis Code Z80Family history of primary malignant neoplasm

ICD-10-CM Codes›Z00–Z99›Z77-Z99›Z80

ICD-10-CM Z80
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

Z80 is a non-billable ICD-10-CM category code for family history of primary malignant neoplasm, so it cannot be submitted on claims. Use a more specific code from this category instead, such as Z80.0, Z80.1, Z80.2, and Z80.3.

Code Identity

ICD-10-CM Code
Z80
Billable Status
No — Non-Billable Category
Code Describes
Family history of primary malignant neoplasm
Short Description
Family history of primary malignant neoplasm
Same as the full description in the CMS dataset.
Chapter
Z77-Z99
Persons with potential health hazards related to family and personal history and certain conditions influencing health status

Code Classification

ChapterZ00–Z99Factors influencing health status and contact with health services
SectionZ77-Z99Persons with potential health hazards related to family and personal history and certain conditions influencing health status
CategoryZ80Family history of primary malignant neoplasm
This CodeZ80Family history of primary malignant neoplasm

Specific Coding for Family history of primary malignant neoplasmOverview

Non-specific codes like Z80 require more characters. Use one of these billable codes instead:

  • Use Z80.0 for Family history of malignant neoplasm of digestive organs

  • Use Z80.1 for Family history of malignant neoplasm of trachea, bronchus and lung

  • Use Z80.2 for Family history of malignant neoplasm of other respiratory and intrathoracic organs

  • Use Z80.3 for Family history of malignant neoplasm of breast

  • Z80.4 for Family history of malignant neoplasm of genital organs

  • Use Z80.41 for Family history of malignant neoplasm of ovary

  • Use Z80.42 for Family history of malignant neoplasm of prostate

  • Use Z80.43 for Family history of malignant neoplasm of testis

  • Use Z80.44 for Family history of malignant neoplasm of fallopian tube(s)

  • Use Z80.49 for Family history of malignant neoplasm of other genital organs

  • Z80.5 for Family history of malignant neoplasm of urinary tract

  • Use Z80.51 for Family history of malignant neoplasm of kidney

  • Use Z80.52 for Family history of malignant neoplasm of bladder

  • Use Z80.59 for Family history of malignant neoplasm of other urinary tract organ

  • Use Z80.6 for Family history of leukemia

  • Use Z80.7 for Family history of other malignant neoplasms of lymphoid, hematopoietic and related tissues

  • Use Z80.8 for Family history of malignant neoplasm of other organs or systems

  • Use Z80.9 for Family history of malignant neoplasm, unspecified

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to Z80: its own notes plus those printed at block Z77-Z99 and Chapter 21. A note printed at a category, block or chapter applies to every code under it.

Code Also

A second code may be needed to fully describe the condition; the note gives no sequencing direction.

From Block Z77-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status applies to 567 codes
  • any follow-up examination (Z08-Z09)

Notes

General instructions on how these codes are used.

From Chapter 21 (Z00-Z99) Factors influencing health status and contact with health services applies to 1,425 codes
  • Z codes represent reasons for encounters. A corresponding procedure code must accompany a Z code if a procedure is performed. Categories Z00-Z99 are provided for occasions when circumstances other than a disease, injury or external cause classifiable to categories A00-Y89 are recorded as 'diagnoses' or 'problems'. This can arise in two main ways:
  • (a) When a person who may or may not be sick encounters the health services for some specific purpose, such as to receive limited care or service for a current condition, to donate an organ or tissue, to receive prophylactic vaccination (immunization), or to discuss a problem which is in itself not a disease or injury.
  • (b) When some circumstance or problem is present which influences the person's health status but is not in itself a current illness or injury.

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name Z80, its category, or a range that includes it.

Use Additional Code 2

These codes say to use an additional code from the note, and Z80 is one of the codes named.

  • Z12 Encounter for screening for malignant neoplasms
    code to identify any family history of malignant neoplasm (Z80.-)
  • Z15 Genetic susceptibility to disease
    code, if applicable, for any associated family history of the disease (Z80-Z84)

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Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About Z80Overview

What is the ICD-10 code for family history of primary malignant neoplasm?

Z80 is the ICD-10-CM category for family history of primary malignant neoplasm, but it is a non-billable header: claims need a more specific code from this category, listed on this page.

Is Z80 (Family history of primary malignant neoplasm) a billable code?

No. This is a category header that groups the codes for family history of primary malignant neoplasm, and headers cannot be submitted on claims. Claims for family history of primary malignant neoplasm need a more specific code from this category, such as Z80.0, Z80.1, and Z80.2.