2026 ICD-10-CM Diagnosis Code Z79.890Hormone replacement therapy

ICD-10-CM Codes›Z00–Z99›Z77-Z99›current

ICD-10-CM Z79.890
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

Z79.890 is a billable ICD-10-CM diagnosis code for hormone replacement therapy. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The code is not accepted as a principal diagnosis by the Medicare Code Editor and exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Other specified status.

Code Identity

ICD-10-CM Code
Z79.890
Billable Status
Yes — Valid for Submission
Code Describes
Hormone replacement therapy
Short Description
Hormone replacement therapy
Same as the full description in the CMS dataset.
Parent Code
Z79.89
Other long term (current) drug therapy

Code Classification

ChapterZ00–Z99Factors influencing health status and contact with health services
SectionZ77-Z99Persons with potential health hazards related to family and personal history and certain conditions influencing health status
CategorycurrentLong term drug therapy (Z79)
This CodeZ79.890Hormone replacement therapy

Code EditsBilling

Medicare Code Editor checks that affect claim validity for Z79.890.

Unacceptable principal diagnosis
There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Present on Admission (POA)Billing

Z79.890 is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Female to male transsexual person on hormone therapy
  • Female-to-male transsexual
  • Hormone replacement monitoring check done
  • Hormone replacement monitoring status
  • Hormone replacement therapy bleed pattern - abnormal
  • Hormone replacement therapy bleed pattern - no bleeding
  • Hormone replacement therapy bleed pattern - not relevant
  • Hormone replacement therapy started
  • HRT side-effects
  • HRT: combined estrogen/progestogen
  • HRT: unopposed estrogen
  • Long-term current use of postmenopausal hormone replacement therapy
  • Long-term current use of steroid
  • Long-term current use of testosterone replacement therapy
  • Long-term current use of thyroid hormone replacement therapy
  • Male to female transsexual person on hormone therapy
  • Male-to-female transsexual
  • Menopause monitoring status
  • Transsexual
  • Years on hormone replacement therapy

Index to Diseases and InjuriesGuidance

Alphabetical index entries that point to this code.

External Cause of Injuries IndexGuidance

References for this code in the External Cause of Injuries Index.

    • Long-term(current) (prophylactic) drug therapy (use of)
      • hormone replacement
    • Therapy
      • drug, long-term (current) (prophylactic)
        • hormone replacement

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR FAC025
Other specified status
Default principal diagnosis: inpatient No · outpatient Yes

Clinical InformationClinical

  • Estrogen Replacement Therapy

    the use of hormonal agents with estrogen-like activity in postmenopausal or other estrogen-deficient women to alleviate effects of hormone deficiency, such as vasomotor symptoms, dyspareunia, and progressive development of osteoporosis. this may also include the use of progestational agents in combination therapy.

  • Hormone Replacement Therapy

    therapeutic use of hormones to alleviate the effects of hormone deficiency.

  • Female-to-Male Transsexual Animal|Female-to-Male Transsexual

    an organism that was female at birth based on physical characteristics and has undergone hormonal therapy and/or surgical procedures in order to develop more male physical characteristics.

  • Female-to-Male Transsexual Phenotype|Female-to-Male Transsexual

    an individual who was female at birth based on physical characteristics and has undergone hormonal therapy and/or surgical procedures in order to develop more male physical characteristics.

  • Female-to-Male Transsexual|F-to-M|F2M|FTM|Female-to-Male Transsexual, Self-Report|TM|Trans Man|Transgender Male|Transgender male|Transman|Transsexual Male|Transsexual Man

    a person who was assigned to the female gender at birth based on physical characteristics but who self-identifies psychologically and emotionally as male.

  • Male-to-Female Transsexual Animal|Male-to-Female Transsexual

    an organism that was male at birth based on physical characteristics and has undergone hormonal therapy and/or surgical procedures in order to develop more female physical characteristics.

  • Male-to-Female Transsexual Phenotype|Male-to-Female Transsexual

    an individual who was male at birth based on physical characteristics and has undergone hormonal therapy and/or surgical procedures in order to develop more female physical characteristics.

  • Male-to-Female Transsexual|M-to-F|M2F|MTF|Male-to-Female Transsexual, Self-Report|TF|Trans Female|Trans Woman|Transgender Female|Transgender female|Transsexual Female|Transwoman

    a person who was assigned to the male gender at birth based on physical characteristics but who self-identifies psychologically and emotionally as female.

  • Transsexual

    a person who was assigned to one gender at birth based on physical characteristics but who self-identifies psychologically and emotionally as the other.

Patient EducationClinical

Hormone Replacement Therapy

Menopause is the time in a woman's life when her period stops. It is a normal part of aging. In the years before and during menopause, the levels of female hormones can go up and down. This can cause symptoms such as hot flashes, night sweats, pain during sex, and vaginal dryness.

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert Z79.890 to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
V07.4 Hormone replace postmeno
Exact Match The mapping is direct, with no qualifiers.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About Z79.890Overview

Is Z79.890 (Other long term (current) drug therapy) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report hormone replacement therapy on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

Can Z79.890 be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because hormone replacement therapy describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.

Is Z79.890 exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for hormone replacement therapy on inpatient claims.

What is the ICD-9 equivalent of Z79.890?

Under the General Equivalence Mappings, hormone replacement therapy converts to ICD-9-CM V07.4 (hormone replace postmeno). The mapping is a direct match.