ICD-10-CM Long-term (current) (prophylactic) drug therapy (use of) References

"Long-term (current) (prophylactic) drug therapy (use of)" Annotation Back-References in the ICD-10-CM Index to Diseases and Injuries

Browse the ICD-10-CM codes with references applicable to the clinical term "long-term (current) (prophylactic) drug therapy (use of)"

  • Long-term (current) (prophylactic) drug therapy (use of)
    • 5-fluorouracil - Z79.631 Long term (current) use of antimetabolite agent
    • 6-mercaptopurine - Z79.631 Long term (current) use of antimetabolite agent
    • adalimumab - Z79.620 Long term (current) use of immunosuppressive biologic
    • agents affecting estrogen receptors and estrogen levels NEC - Z79.818 Long term (current) use of other agents affecting estrogen receptors and estrogen levels
    • alkylating agent - Z79.630 Long term (current) use of alkylating agent
    • anastrozole (Arimidex) - Z79.811 Long term (current) use of aromatase inhibitors
    • antibiotics - Z79.2 Long term (current) use of antibiotics
      • short-term use - omit code
    • anticoagulants - Z79.01 Long term (current) use of anticoagulants
    • antidiabetic drugs, injectable, non-insulin - Z79.85 Long-term (current) use of injectable non-insulin antidiabetic drugs
    • anti-inflammatory, non-steroidal (NSAID) - Z79.1 Long term (current) use of non-steroidal anti-inflammatories (NSAID)
    • antimetabolite agent - Z79.631 Long term (current) use of antimetabolite agent
    • antiplatelet - Z79.02 Long term (current) use of antithrombotics/antiplatelets
    • antithrombotics - Z79.02 Long term (current) use of antithrombotics/antiplatelets
    • antitumor antibiotic - Z79.632 Long term (current) use of antitumor antibiotic
    • apremilast - Z79.61 Long term (current) use of immunomodulator
    • aromatase inhibitors - Z79.811 Long term (current) use of aromatase inhibitors
    • aspirin - Z79.82 Long term (current) use of aspirin
    • azathioprine - Z79.624 Long term (current) use of inhibitors of nucleotide synthesis
    • birth control pill or patch - Z79.3 Long term (current) use of hormonal contraceptives
    • bisphosphonates - Z79.83 Long term (current) use of bisphosphonates
    • bleomycin - Z79.632 Long term (current) use of antitumor antibiotic
    • calcineurin inhibitor - Z79.621 Long term (current) use of calcineurin inhibitor
    • chlorambucil - Z79.630 Long term (current) use of alkylating agent
    • cisplatin - Z79.630 Long term (current) use of alkylating agent
    • contraceptive, oral - Z79.3 Long term (current) use of hormonal contraceptives
    • cyclophosphamide - Z79.630 Long term (current) use of alkylating agent
    • cyclosporine - Z79.621 Long term (current) use of calcineurin inhibitor
    • cytarabine - Z79.631 Long term (current) use of antimetabolite agent
    • doxorubicin - Z79.632 Long term (current) use of antitumor antibiotic
    • drug, specified NEC - Z79.899 Other long term (current) drug therapy
    • estrogen receptor downregulators - Z79.818 Long term (current) use of other agents affecting estrogen receptors and estrogen levels
    • etanercept - Z79.620 Long term (current) use of immunosuppressive biologic
    • etoposide - Z79.634 Long term (current) use of topoisomerase inhibitor
    • Evista - Z79.810 Long term (current) use of selective estrogen receptor modulators (SERMs)
    • exemestane (Aromasin) - Z79.811 Long term (current) use of aromatase inhibitors
    • Fareston - Z79.810 Long term (current) use of selective estrogen receptor modulators (SERMs)
    • fulvestrant (Faslodex) - Z79.818 Long term (current) use of other agents affecting estrogen receptors and estrogen levels
    • gonadotropin-releasing hormone (GnRH) agonist - Z79.818 Long term (current) use of other agents affecting estrogen receptors and estrogen levels
    • goserelin acetate (Zoladex) - Z79.818 Long term (current) use of other agents affecting estrogen receptors and estrogen levels
    • hormone replacement - Z79.890 Hormone replacement therapy
    • hydroxyurea - Z79.64 Long term (current) use of myelosuppressive agent
    • immunomodulators, unspecified - Z79.60 Long term (current) use of unspecified immunomodulators and immunosuppressants
      • specified NEC - Z79.69 Long term (current) use of other immunomodulators and immunosuppressants
    • immunomodulatory imide drug - Z79.61 Long term (current) use of immunomodulator
    • immunosuppressants, unspecified - Z79.60 Long term (current) use of unspecified immunomodulators and immunosuppressants
      • specified NEC - Z79.69 Long term (current) use of other immunomodulators and immunosuppressants
    • immunosuppressive biologic - Z79.620 Long term (current) use of immunosuppressive biologic
    • infliximab - Z79.620 Long term (current) use of immunosuppressive biologic
    • inhibitors of nucleotide synthesis - Z79.624 Long term (current) use of inhibitors of nucleotide synthesis
    • insulin - Z79.4 Long term (current) use of insulin
    • irinotecan - Z79.634 Long term (current) use of topoisomerase inhibitor
    • Janus kinase inhibitor - Z79.622 Long term (current) use of Janus kinase inhibitor
    • lenalidomide - Z79.61 Long term (current) use of immunomodulator
    • letrozole (Femara) - Z79.811 Long term (current) use of aromatase inhibitors
    • leuprolide acetate (leuprorelin) (Lupron) - Z79.818 Long term (current) use of other agents affecting estrogen receptors and estrogen levels
    • mammalian target of rapamycin (mTOR) inhibitor - Z79.623 Long term (current) use of mammalian target of rapamycin (mTOR) inhibitor
    • megestrol acetate (Megace) - Z79.818 Long term (current) use of other agents affecting estrogen receptors and estrogen levels
    • methadone for pain management - Z79.891 Long term (current) use of opiate analgesic
    • mitomycin C - Z79.632 Long term (current) use of antitumor antibiotic
    • mitotic inhibitor - Z79.633 Long term (current) use of mitotic inhibitor
    • monoclonal antibodies - Z79.620 Long term (current) use of immunosuppressive biologic
    • myelosuppressive agent - Z79.64 Long term (current) use of myelosuppressive agent
    • Nolvadex - Z79.810 Long term (current) use of selective estrogen receptor modulators (SERMs)
    • non-insulin antidiabetic drug, injectable - Z79.899 Other long term (current) drug therapy
    • non-steroidal anti-inflammatories (NSAID) - Z79.1 Long term (current) use of non-steroidal anti-inflammatories (NSAID)
    • omycophenolate - Z79.624 Long term (current) use of inhibitors of nucleotide synthesis
    • opiate analgesic - Z79.891 Long term (current) use of opiate analgesic
    • oral
      • antidiabetic - Z79.84 Long term (current) use of oral hypoglycemic drugs
      • contraceptive - Z79.3 Long term (current) use of hormonal contraceptives
      • hypoglycemic - Z79.84 Long term (current) use of oral hypoglycemic drugs
    • paclitaxel - Z79.633 Long term (current) use of mitotic inhibitor
    • plant alkaloids - Z79.633 Long term (current) use of mitotic inhibitor
    • pomalidomide - Z79.61 Long term (current) use of immunomodulator
    • purine synthesis (IMDH) inhibitors - Z79.624 Long term (current) use of inhibitors of nucleotide synthesis
    • raloxifene (Evista) - Z79.810 Long term (current) use of selective estrogen receptor modulators (SERMs)
    • selective estrogen receptor modulators (SERMs) - Z79.810 Long term (current) use of selective estrogen receptor modulators (SERMs)
    • sirolimus - Z79.623 Long term (current) use of mammalian target of rapamycin (mTOR) inhibitor
    • steroids
      • inhaled - Z79.51 Long term (current) use of inhaled steroids
      • systemic - Z79.52 Long term (current) use of systemic steroids
    • tacrolimus - Z79.621 Long term (current) use of calcineurin inhibitor
    • tamoxifen (Nolvadex) - Z79.810 Long term (current) use of selective estrogen receptor modulators (SERMs)
    • tofacitinib - Z79.622 Long term (current) use of Janus kinase inhibitor
    • topoisomerase inhibitor - Z79.634 Long term (current) use of topoisomerase inhibitor
    • topotecan - Z79.634 Long term (current) use of topoisomerase inhibitor
    • toremifene (Fareston) - Z79.810 Long term (current) use of selective estrogen receptor modulators (SERMs)
    • vinblastine - Z79.633 Long term (current) use of mitotic inhibitor
    • vincristine - Z79.633 Long term (current) use of mitotic inhibitor

Applicable Clinical Terms Definitions

Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.

Adalimumab: A humanized monoclonal antibody that binds specifically to TNF-ALPHA and blocks its interaction with endogenous TNF RECEPTORS to modulate INFLAMMATION. It is used in the treatment of RHEUMATOID ARTHRITIS; PSORIATIC ARTHRITIS; CROHN'S DISEASE and ULCERATIVE COLITIS.

Anticoagulants: Agents that prevent BLOOD CLOTTING.

Aromatase Inhibitors: Compounds that inhibit AROMATASE in order to reduce production of estrogenic steroid hormones.

Aspirin: The prototypical analgesic used in the treatment of mild to moderate pain. It has anti-inflammatory and antipyretic properties and acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. (From Martindale, The Extra Pharmacopoeia, 30th ed, p5)

Bleomycin: A complex of related glycopeptide antibiotics from Streptomyces verticillus consisting of bleomycin A2 and B2. It inhibits DNA metabolism and is used as an antineoplastic, especially for solid tumors.

Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)

Cisplatin: An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.

Cyclophosphamide: Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active aldophosphamide. It has been used in the treatment of LYMPHOMA and LEUKEMIA. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer.

Cyclosporine: A cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation. (From Martindale, The Extra Pharmacopoeia, 30th ed).

Cytarabine: A pyrimidine nucleoside analog that is used mainly in the treatment of leukemia, especially acute non-lymphoblastic leukemia. Cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. Its actions are specific for the S phase of the cell cycle. It also has antiviral and immunosuppressant properties. (From Martindale, The Extra Pharmacopoeia, 30th ed, p472)

Doxorubicin: Antineoplastic antibiotic obtained from Streptomyces peucetius. It is a hydroxy derivative of DAUNORUBICIN.

Etanercept: A recombinant version of soluble human TNF receptor fused to an IgG FC fragment that binds specifically to TUMOR NECROSIS FACTOR and inhibits its binding with endogenous TNF receptors. It prevents the inflammatory effect of TNF and is used to treat RHEUMATOID ARTHRITIS; PSORIATIC ARTHRITIS and ANKYLOSING SPONDYLITIS.

Etoposide: A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.

Infliximab: A chimeric monoclonal antibody to TNF-ALPHA that is used in the treatment of RHEUMATOID ARTHRITIS; ANKYLOSING SPONDYLITIS; PSORIATIC ARTHRITIS and CROHN'S DISEASE.

Insulin: A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).

Irinotecan: A semisynthetic camptothecin derivative that inhibits DNA TOPOISOMERASE I to prevent nucleic acid synthesis during S PHASE. It is used as an antineoplastic agent for the treatment of COLORECTAL NEOPLASMS and PANCREATIC NEOPLASMS.

Lenalidomide: A phthalimide and piperidone derivative that has immunomodulatory and antiangiogenic properties. It is used for the treatment of transfusion-dependent anemia in MYELODYSPLASTIC SYNDROMES, and for the treatment of MULTIPLE MYELOMA, and relapsed or refractory MANTLE CELL LYMPHOMA.

Paclitaxel: A cyclodecane isolated from the bark of the Pacific yew tree, TAXUS BREVIFOLIA. It stabilizes MICROTUBULES in their polymerized form leading to cell death.

Sirolimus: A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.

Steroids: A group of polycyclic compounds closely related biochemically to TERPENES. They include cholesterol, numerous hormones, precursors of certain vitamins, bile acids, alcohols (STEROLS), and certain natural drugs and poisons. Steroids have a common nucleus, a fused, reduced 17-carbon atom ring system, cyclopentanoperhydrophenanthrene. Most steroids also have two methyl groups and an aliphatic side-chain attached to the nucleus. (From Hawley's Condensed Chemical Dictionary, 11th ed)

Tacrolimus: A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro.

Topotecan: An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA TOPOISOMERASES, TYPE I.

Vinblastine: Antitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.)

Vincristine: An antitumor alkaloid isolated from VINCA ROSEA. (Merck, 11th ed.)