2026 ICD-10-CM Diagnosis Code T50.904SPoisoning by unspecified drugs, medicaments and biological substances, undetermined, sequela

ICD-10-CM CodesS00–T88T36-T50T50

ICD-10-CM T50.904S
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

T50.904S is a billable ICD-10-CM diagnosis code for poisoning by unspecified drugs, medicaments and biological substances, undetermined, sequela. The 7th character S marks it as a sequela code, which reports a problem that remains after the original condition has resolved. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 922 through 923. The code is exempt from POA reporting. Coders also document this condition as congenital arthrogryposis caused by teratogen. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Poisoning/toxic effect/adverse effects/underdosing, sequela.

Code Identity

ICD-10-CM Code
T50.904S
Billable Status
Yes — Valid for Submission
Code Describes
Poisoning by unspecified drugs, medicaments and biological substances, undetermined, sequela
Short Description
Poisoning by unsp drug/meds/biol subst, undet, sequela
Parent Code
Poisoning by unspecified drugs, medicaments and biological substances, undetermined

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT50Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances
This CodeT50.904SPoisoning by unspecified drugs, medicaments and biological substances, undetermined, sequela

Present on Admission (POA)Billing

T50.904S is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Congenital arthrogryposis caused by teratogen
  • Gynecomastia
  • Gynecomastia caused by drug
  • Hypertrophy of breast
  • Poisoning by drug AND/OR medicinal substance

Coding GuidelinesGuidance

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined). If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances (T50). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ075
Poisoning/toxic effect/adverse effects/underdosing, sequela
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Gynecomastia

    enlargement of the breast in the males, caused by an excess of estrogens. physiological gynecomastia is normally observed in newborns; adolescent; and aging males.
  • Gynecomastia, CTCAE|Gynecomastia|Gynecomastia|Gynecomastia (Priority 2)|Gynecomastia, CTCAE 5.0

    a disorder characterized by excessive development of the breasts in males.
  • 17-Beta-Hydroxysteroid Dehydrogenase 3 Deficiency|17 Beta HSD3 Deficiency|17 beta HSD3 Deficiency|Pseudohermaphroditism, Male, with Gynecomastia

    decreased activity of the steroidogenic enzyme, 17-beta-hydroxysteroid dehydrogenase, associated with mutation(s) in the hsd17b3 gene, leading to reduced testosterone production.
  • Grade 1 Gynecomastia, CTCAE|Grade 1 Gynecomastia

    asymptomatic
  • Grade 2 Gynecomastia, CTCAE|Grade 2 Gynecomastia|Grade 2 Gynecomastia

    symptomatic (e.g., pain or psychosocial impact)
  • Grade 3 Gynecomastia, CTCAE|Grade 3 Gynecomastia|Grade 3 Gynecomastia

    severe symptoms; elective operative intervention indicated
  • Gynecomastia

    a non-neoplastic focal or diffuse proliferation of glandular tissue of breast in males.
  • Gynecomastia, CTCAE 5.0|Gynecomastia|Gynecomastia|Gynecomastia (Priority 2)

    a disorder characterized by excessive development of the breasts in males.
  • Pathological Gynecomastia

    gynecomastia that is due to exogenous substances or disease processes.
  • Pubertal Gynecomastia|Transient Gynecomastia|Transient Gynecomastia

    gynecomastia that occurs during puberty and is not due to exogenous substances or disease processes.

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
Acidifying agent NECT50.901T50.902T50.903T50.904T50.905T50.906
Adjunct, pharmaceuticalT50.901T50.902T50.903T50.904T50.905T50.906
Alkalinizing agents (medicinal)T50.901T50.902T50.903T50.904T50.905T50.906
Alkalizing agent NECT50.901T50.902T50.903T50.904T50.905T50.906
Biological substance NECT50.901T50.902T50.903T50.904T50.905T50.906
Dietetic drug NECT50.901T50.902T50.903T50.904T50.905T50.906
Drug NECT50.901T50.902T50.903T50.904T50.905T50.906
Drug NEC::specified NECT50.901T50.902T50.903T50.904T50.905T50.906
Elemental dietT50.901T50.902T50.903T50.904T50.905T50.906
Excipients, pharmaceuticalT50.901T50.902T50.903T50.904T50.905T50.906
Headache cures, drugs, powders NECT50.901T50.902T50.903T50.904T50.905T50.906
Lactose (as excipient)T50.901T50.902T50.903T50.904T50.905T50.906
Lipotropic drug NECT50.901T50.902T50.903T50.904T50.905T50.906
Medicament NECT50.901T50.902T50.903T50.904T50.905T50.906
Nutritional supplementT50.901T50.902T50.903T50.904T50.905T50.906
PharmaceuticalT50.901T50.902T50.903T50.904T50.905T50.906
Pharmaceutical::adjunct NECT50.901T50.902T50.903T50.904T50.905T50.906
Pharmaceutical::excipient NECT50.901T50.902T50.903T50.904T50.905T50.906
Pharmaceutical::sweetenerT50.901T50.902T50.903T50.904T50.905T50.906
Pharmaceutical::viscous agentT50.901T50.902T50.903T50.904T50.905T50.906
SaccharinT50.901T50.902T50.903T50.904T50.905T50.906
Salt substituteT50.901T50.902T50.903T50.904T50.905T50.906
Salt-replacing drugT50.901T50.902T50.903T50.904T50.905T50.906
Sodium-free saltT50.901T50.902T50.903T50.904T50.905T50.906
Soothing syrupT50.901T50.902T50.903T50.904T50.905T50.906
StarchT50.901T50.902T50.903T50.904T50.905T50.906
Stone-dissolving drugT50.901T50.902T50.903T50.904T50.905T50.906
SweetenerT50.901T50.902T50.903T50.904T50.905T50.906
Tablets [See Also: specified substance]T50.901T50.902T50.903T50.904T50.905T50.906
Tonic NECT50.901T50.902T50.903T50.904T50.905T50.906
Viscous agentT50.901T50.902T50.903T50.904T50.905T50.906

Patient EducationClinical

Poisoning

A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it, or absorb it through your skin. Any substance can be poisonous if too much is taken. Poisons can include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T50.904S to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
909.0 Late eff drug poisoning
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
E989 Late eff inj-undet circ
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About T50.904SOverview

Is T50.904S a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report poisoning by unspecified drugs, medicaments and biological substances, undetermined, sequela on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What does the 7th character S in T50.904S mean?

The final character S makes this a sequela code: it reports a lingering problem that remains after the poisoning by unspecified drugs, medicaments and biological substances, undetermined itself has resolved, not the original event.

What MS-DRG does T50.904S group to?

When poisoning by unspecified drugs, medicaments and biological substances, undetermined, sequela is the principal diagnosis on an inpatient stay, it groups to MS-DRG 922, 923, with relative weights from 1.0177 to 1.7494 depending on complications. Higher weights mean higher Medicare reimbursement.

Is T50.904S exempt from POA reporting?

Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for poisoning by unspecified drugs, medicaments and biological substances, undetermined, sequela on inpatient claims.

What is the ICD-9 equivalent of T50.904S?

Under the General Equivalence Mappings, poisoning by unspecified drugs, medicaments and biological substances, undetermined, sequela converts to ICD-9-CM 909.0 (late eff drug poisoning) and E989 (late eff inj-undet circ). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.