2027 ICD-10-CM Diagnosis Code T50.3X2APoisoning by electrolytic, caloric and water-balance agents, intentional self-harm, initial encounter

ICD-10-CM Codes›S00–T88›T36-T50›T50

ICD-10-CM T50.3X2A
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

T50.3X2A is a billable ICD-10-CM diagnosis code for poisoning by electrolytic, caloric and water-balance agents, intentional self-harm, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 917 through 918. Coders also document this condition as electrolyte agent poisoning. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under External cause codes: intent of injury, self-harm; External cause codes: poisoning by drug; and Poisoning by drugs, initial encounter.

For Medicare Advantage risk adjustment, T50.3X2A maps to CMS-HCC Category 155 (Major Depression, Moderate or Severe, without Psychosis) under the V28 model, adding a risk factor of about 0.299 for a community, non-dual, aged beneficiary in payment year 2027.

Code Identity

ICD-10-CM Code
T50.3X2A
Billable Status
Yes — Valid for Submission
Code Describes
Poisoning by electrolytic, caloric and water-balance agents, intentional self-harm, initial encounter
Short Description
Poisn by electrolytic/caloric/wtr-bal agnt, self-harm, init
Parent Code
Poisoning by electrolytic, caloric and water-balance agents, intentional self-harm

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT50Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances
This CodeT50.3X2APoisoning by electrolytic, caloric and water-balance agents, intentional self-harm, initial encounter

Medicare Risk Adjustment (HCC)Billing

T50.3X2A maps to a payment category in the CMS-HCC model used to risk-adjust Medicare Advantage payments. Weights are the published community factors for payment year 2027.

CMS-HCC V28 Category (Payment Model)
HCC 155— Major Depression, Moderate or Severe, without Psychosis
Payment HCC · PY 2027 one of 371 ICD-10-CM codes in this category
Risk Adjustment Factor (RAF) Weight
+0.299
community, non-dual, aged · ranges 0.108–0.316 across segments
Hierarchy
Superseded by HCC 151, HCC 152, HCC 153, and HCC 154
a more severe related category takes the payment when both are reported
Prior Model (CMS-HCC V24)
HCC 59
V24 retired V28 pays 100% of MA risk scores since PY 2026
Other CMS Models
PACE (CMS-HCC V22): HCC 58 · ESRD (V21): HCC 58 · ESRD (V24): HCC 59
ESRD V21 weights: 0.091 dialysis, 0.217–0.260 functioning graft · ESRD V24 weights: 0.066 dialysis, 0.129–0.259 functioning graft
Part D (RxHCC)
RxHCC 132 — Depression
also risk-adjusts in the Part D prescription drug model (V08)

Source: CMS Payment Year 2027 risk adjustment mappings and model software. Weights are relative factors, not dollar amounts; a beneficiary's total RAF also includes demographics and interactions. Browse all CMS-HCC categories.

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Electrolyte agent poisoning
  • Intentional electrolyte agent poisoning
  • Intentional potassium overdose
  • Intentional tryptophan overdose
  • Intentional tryptophan poisoning
  • Potassium overdose
  • Potassium poisoning
  • Tryptophan overdose
  • Tryptophan poisoning

Coding GuidelinesGuidance

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined). If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances (T50). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027, published by CMS and the National Center for Health Statistics.

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to T50.3X2A: its own notes plus those printed at T50, block T36-T50, and Chapter 19. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • adverse effect of correct substance properly administered
  • poisoning by overdose of substance
  • poisoning by wrong substance given or taken in error
  • underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • toxic reaction to local anesthesia in pregnancy (O29.3-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • abuse and dependence of psychoactive substances (F10-F19)
  • abuse of non-dependence-producing substances (F55.-)
  • immunodeficiency due to drugs (D84.821)
  • drug reaction and poisoning affecting newborn (P00-P96)
  • pathological drug intoxication (inebriation) (F10-F19)
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes

Code First

The underlying condition named in the note is sequenced before this code.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • for adverse effects, the nature of the adverse effect, such as:
  • adverse effect NOS (T88.7)
  • aspirin gastritis (K29.-)
  • blood disorders (D56-D76)
  • contact dermatitis (L23-L25)
  • dermatitis due to substances taken internally (L27.-)
  • nephropathy (N14.0-N14.2)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • code(s) to specify:
  • manifestations of poisoning
  • underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
  • underdosing of medication regimen (Z91.12-, Z91.13-)
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes
  • code to identify any retained foreign body, if applicable (Z18.-)

Notes

General instructions on how these codes are used.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • The drug giving rise to the adverse effect should be identified by use of codes from categories T36-T50 with fifth or sixth character 5.
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes
  • Use secondary code(s) from Chapter 20, External causes of morbidity, to indicate cause of injury. Codes within the T section that include the external cause do not require an additional external cause code
  • The chapter uses the S-section for coding different types of injuries related to single body regions and the T-section to cover injuries to unspecified body regions as well as poisoning and certain other consequences of external causes.

7th Character

Every code in the category takes a 7th character from the listed values, with the placeholder X filling any empty positions before it.

From T50 Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances applies to 342 codes
  • The appropriate 7th character is to be added to each code from category T50
  • Ainitial encounter this code
  • Dsubsequent encounter
  • Ssequela

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name T50.3X2A, its category, or a range that includes it.

Use Additional Code 1

These codes say to use an additional code from the note, and T50.3X2A is one of the codes named.

  • G61.1 Serum neuropathy
    code for adverse effect, if applicable, to identify serum (T50.-) names T50.-, which includes this code

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR EXT021
External cause codes: intent of injury, self-harm
Default principal diagnosis: inpatient No · outpatient No
CCSR EXT014
External cause codes: poisoning by drug
Default principal diagnosis: inpatient No · outpatient No
CCSR INJ022
Poisoning by drugs, initial encounter
Default principal diagnosis: inpatient No · outpatient No
CCSR MBD012
Suicidal ideation/attempt/intentional self-harm
Default principal diagnosis: inpatient Yes · outpatient Yes

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
Acetic::acid::irrigating solutionT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Amino acidsT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Aminoacetic acid (derivatives)T50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
AntikalureticT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
CalciumT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Calcium::glubionateT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Calcium::gluconateT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Calcium::gluconogalactogluconateT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Calcium::lactateT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Calcium::phosphateT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Calcium::saltsT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Caloric agentT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Carbacrylamine (resin)T50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Cation exchange resinT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
DextroseT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Dialysis solution (intraperitoneal)T50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Electrolyte balance drugT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Electrolytes NECT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Electrolytic agent NECT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
FructoseT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
GalactoseT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
GlucoseT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Glucose::with sodium chlorideT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Glycerol::intravenousT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
GlycineT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Hartmann's solutionT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Invert sugarT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Ion exchange resin::cationT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Lactated potassic salineT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
LevuloseT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Magnesium NEC::silicofluorideT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Mineral::salt NECT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Oral rehydration saltsT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Peritoneal dialysis solutionT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Polyaminostyrene resinsT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Potassic saline injection (lactated)T50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Potassium (salts) NECT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Potassium (salts) NEC::chlorideT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Potassium-removing resinT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Potassium-retaining drugT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Rehydration salts (oral)T50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Replacement solutionT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Ringer (lactate) solutionT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Sodium::acid phosphateT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Sodium::biphosphateT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Sodium::chlorideT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Sodium::chloride::with glucoseT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Sodium::cyclamateT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Sodium::free saltT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Sodium::hydrogen carbonateT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Sodium::polystyrene sulfonateT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Sodium::removing resinsT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Sodium::salt NECT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Sodium-removing resinT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
SucroseT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
TravertT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Water::balance drugT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Water::distilledT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6
Water::purifiedT50.3X1T50.3X2T50.3X3T50.3X4T50.3X5T50.3X6

Patient EducationClinical

Poisoning

A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it, or absorb it through your skin. Any substance can be poisonous if too much is taken. Poisons can include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T50.3X2A to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
974.5 Pois-electro/cal/wat agt
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
E950.4 Poison-drug/medicin NEC
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About T50.3X2AOverview

Is T50.3X2A a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report poisoning by electrolytic, caloric and water-balance agents, intentional self-harm, initial encounter on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What does the 7th character A in T50.3X2A mean?

The final character A marks the initial encounter: use it while the patient is receiving active treatment for poisoning by electrolytic, caloric and water-balance agents, intentional self-harm, such as an emergency visit or first evaluation.

What MS-DRG does T50.3X2A group to?

When poisoning by electrolytic, caloric and water-balance agents, intentional self-harm, initial encounter is the principal diagnosis on an inpatient stay, it groups to MS-DRG 918, 917, with relative weights from 0.8716 to 1.5698 depending on complications. Higher weights mean higher Medicare reimbursement.

Can T50.3X2A be reported with a code from O29.3?

Not as a rule. The Excludes1 note at block T36-T50, which applies to T50.3X2A, lists "toxic reaction to local anesthesia in pregnancy (O29.3-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).

What is the ICD-9 equivalent of T50.3X2A?

Under the General Equivalence Mappings, poisoning by electrolytic, caloric and water-balance agents, intentional self-harm, initial encounter converts to ICD-9-CM 974.5 (pois-electro/cal/wat agt) and E950.4 (poison-drug/medicin NEC). The mapping is approximate, so confirm the match fits the documentation.

What HCC is T50.3X2A?

T50.3X2A (poisoning by electrolytic, caloric and water-balance agents, intentional self-harm, initial encounter) maps to CMS-HCC Category 155 (Major Depression, Moderate or Severe, without Psychosis), commonly written as HCC 155, in the CMS-HCC V28 model used for Medicare Advantage risk adjustment in payment year 2027. It mapped to HCC 59 under the retired V24 model. It also maps in the PACE (CMS-HCC V22), ESRD (V21), and ESRD (V24) models. In the Part D prescription drug model it maps to RxHCC 132.

Does T50.3X2A risk-adjust for Medicare Advantage payment?

Yes. When documented and reported on a Medicare Advantage encounter, T50.3X2A adds a risk adjustment factor of about 0.299 to the beneficiary's RAF score for a community, non-dual, aged enrollee (published V28 weights range from 0.108 to 0.316 depending on the payment segment). A more severe related category (HCC 151, HCC 152, HCC 153, and HCC 154) supersedes it when both are reported. See the full factor table on the HCC 155 category page.