2026 ICD-10-CM Diagnosis Code T50.1X6AUnderdosing of loop [high-ceiling] diuretics, initial encounter

ICD-10-CM Codes›S00–T88›T36-T50›T50

ICD-10-CM T50.1X6A
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

T50.1X6A is a billable ICD-10-CM diagnosis code for underdosing of loop [high-ceiling] diuretics, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The code is not accepted as a principal diagnosis by the Medicare Code Editor. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Underdosing of drugs and medicaments, initial encounter.

Code Identity

ICD-10-CM Code
T50.1X6A
Billable Status
Yes — Valid for Submission
Code Describes
Underdosing of loop [high-ceiling] diuretics, initial encounter
Short Description
Underdosing of loop diuretics, initial encounter
Parent Code
T50.1X6
Underdosing of loop [high-ceiling] diuretics

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT50Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances
This CodeT50.1X6AUnderdosing of loop [high-ceiling] diuretics, initial encounter

Code EditsBilling

Medicare Code Editor checks that affect claim validity for T50.1X6A.

Unacceptable principal diagnosis
There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Coding GuidelinesGuidance

Underdosing refers to taking less of a medication than is prescribed by a provider or a manufacturer's instruction. Codes for underdosing should never be assigned as principal or first-listed codes. If a patient has a relapse or exacerbation of the medical condition for which the drug is prescribed because of the reduction in dose, then the medical condition itself should be coded.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances (T50). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ029
Underdosing of drugs and medicaments, initial encounter
Default principal diagnosis: inpatient No · outpatient No

Clinical InformationClinical

  • Bumetanide

    a sulfamyl diuretic.

  • Sodium Potassium Chloride Symporter Inhibitors

    agents that inhibit sodium-potassium-chloride symporters which are concentrated in the thick ascending limb at the junction of the loop of henle and kidney tubules, distal. they act as diuretics. excess use is associated with hypokalemia and hyperglycemia.

  • Solute Carrier Family 12, Member 1

    na-k-cl transporter in the ascending limb of loop of henle. it mediates active reabsorption of sodium chloride and is inhibited by loop diuretics such as furosemide; and bumetanide. mutations in the gene encoding slc12a1 are associated with a bartter syndrome.

  • Solute Carrier Family 12, Member 2

    na-k-cl transporter ubiquitously expressed. it plays a key role in salt secretion in epithelial cells and cell volume regulation in nonepithelial cells.

  • Ethacrynic Acid

    a compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of henle, but also in the proximal and distal tubules. this pharmacological action results in excretion of these ions, increased urinary output, and reduction in extracellular fluid. this compound has been classified as a loop or high ceiling diuretic.

  • Furosemide

    a benzoic-sulfonamide-furan. it is a diuretic with fast onset and short duration that is used for edema and chronic renal insufficiency.

  • Ticrynafen

    a novel diuretic with uricosuric action. it has been proposed as an antihypertensive agent.

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect		Under­dosing
BumetanideT50.1X1T50.1X2T50.1X3T50.1X4T50.1X5T50.1X6
EdecrinT50.1X1T50.1X2T50.1X3T50.1X4T50.1X5T50.1X6
Etacrynate sodiumT50.1X1T50.1X2T50.1X3T50.1X4T50.1X5T50.1X6
Etacrynic acidT50.1X1T50.1X2T50.1X3T50.1X4T50.1X5T50.1X6
Ethacrynic acidT50.1X1T50.1X2T50.1X3T50.1X4T50.1X5T50.1X6
EtozolinT50.1X1T50.1X2T50.1X3T50.1X4T50.1X5T50.1X6
FrusemideT50.1X1T50.1X2T50.1X3T50.1X4T50.1X5T50.1X6
FurosemideT50.1X1T50.1X2T50.1X3T50.1X4T50.1X5T50.1X6
LasixT50.1X1T50.1X2T50.1X3T50.1X4T50.1X5T50.1X6
Lyovac Sodium EdecrinT50.1X1T50.1X2T50.1X3T50.1X4T50.1X5T50.1X6
PiretanideT50.1X1T50.1X2T50.1X3T50.1X4T50.1X5T50.1X6
TicrynafenT50.1X1T50.1X2T50.1X3T50.1X4T50.1X5T50.1X6
Tienilic acidT50.1X1T50.1X2T50.1X3T50.1X4T50.1X5T50.1X6

Patient EducationClinical

Medication Errors

Medicines treat infectious diseases, prevent problems from chronic diseases, and ease pain. But medicines can also cause harmful reactions if not used correctly. Errors can happen in the hospital, at the health care provider's office, at the pharmacy, or at home. You can help prevent errors by:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T50.1X6A to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
No Map There is no ICD-9 equivalent for this code.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About T50.1X6AOverview

Is T50.1X6A (Underdosing of loop [high-ceiling] diuretics) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report underdosing of loop [high-ceiling] diuretics, initial encounter on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What does the 7th character A in T50.1X6A mean?

The final character A marks the initial encounter: use it while the patient is receiving active treatment for underdosing of loop [high-ceiling] diuretics, such as an emergency visit or first evaluation.

Can T50.1X6A be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because underdosing of loop [high-ceiling] diuretics, initial encounter describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.