2026 ICD-10-CM Diagnosis Code T49.8X1SPoisoning by other topical agents, accidental (unintentional), sequela

AHRQ’s CCSR groups this code into broader clinical categories.

• Cosmetics

  substances intended to be applied to the human body for cleansing, beautifying, promoting attractiveness, or altering the appearance without affecting the body's structure or functions. included in this definition are skin creams, lotions, perfumes, lipsticks, fingernail polishes, eye and facial makeup preparations, permanent waves, hair colors, toothpastes, and deodorants, as well as any material intended for use as a component of a cosmetic product. (u.s. food & drug administration center for food safety & applied nutrition office of cosmetics fact sheet (web page) feb 1995)

• Hair Preparations

  hair grooming, cleansing and modifying products meant for topical application to hair, usually human. they include sprays, bleaches, dyes, conditioners, rinses, shampoos, nutrient lotions, etc.

• Acidosis, Lactic

  acidosis caused by accumulation of lactic acid more rapidly than it can be metabolized. it may occur spontaneously or in association with diseases such as diabetes mellitus; leukemia; or liver failure.

• Lactic Acid

  a normal intermediate in the fermentation (oxidation, metabolism) of sugar. the concentrated form is used internally to prevent gastrointestinal fermentation. (from stedman, 26th ed)

• Lactobacillales

  an order of gram-positive bacteria in the class bacilli, that have the ability to ferment sugars to lactic acid. they are widespread in nature and commonly used to produce fermented foods.

• Pyruvate Carboxylase Deficiency Disease

  an autosomal recessive metabolic disorder caused by absent or decreased pyruvate carboxylase activity, the enzyme that regulates gluconeogenesis, lipogenesis, and neurotransmitter synthesis. clinical manifestations include lactic acidosis, seizures, respiratory distress, marked psychomotor delay, periodic hypoglycemia, and hypotonia. the clinical course may be similar to leigh disease. (from am j hum genet 1998 jun;62(6):1312-9)

• Pyruvate Dehydrogenase Complex Deficiency Disease

  an inherited metabolic disorder caused by deficient enzyme activity in the pyruvate dehydrogenase complex, resulting in deficiency of acetyl coa and reduced synthesis of acetylcholine. two clinical forms are recognized: neonatal and juvenile. the neonatal form is a relatively common cause of lactic acidosis in the first weeks of life and may also feature an erythematous rash. the juvenile form presents with lactic acidosis, alopecia, intermittent ataxia; seizures; and an erythematous rash. (from j inherit metab dis 1996;19(4):452-62) autosomal recessive and x-linked forms are caused by mutations in the genes for the three different enzyme components of this multisubunit pyruvate dehydrogenase complex. one of the mutations at xp22.2-p22.1 in the gene for the e1 alpha component of the complex leads to leigh disease.

• Podophyllotoxin

  a lignan (lignans) found in podophyllin resin from the roots of podophyllum plants. it is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. it is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives.

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

Medication Errors

Medicines treat infectious diseases, prevent problems from chronic diseases, and ease pain. But medicines can also cause harmful reactions if not used correctly. Errors can happen in the hospital, at the health care provider's office, at the pharmacy, or at home. You can help prevent errors by:

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