2026 ICD-10-CM Diagnosis Code T49.6X6AUnderdosing of otorhinolaryngological drugs and preparations, initial encounter

ICD-10-CM CodesS00–T88T36-T50T49

ICD-10-CM T49.6X6A
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

T49.6X6A is a billable ICD-10-CM diagnosis code for underdosing of otorhinolaryngological drugs and preparations, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The code is not accepted as a principal diagnosis by the Medicare Code Editor. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Underdosing of drugs and medicaments, initial encounter.

Code Identity

ICD-10-CM Code
T49.6X6A
Billable Status
Yes — Valid for Submission
Code Describes
Underdosing of otorhinolaryngological drugs and preparations, initial encounter
Short Description
Underdosing of otorhino drugs and preparations, init
Parent Code
Underdosing of otorhinolaryngological drugs and preparations

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT49Poisoning by, adverse effect of and underdosing of topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinorlaryngological and dental drugs
This CodeT49.6X6AUnderdosing of otorhinolaryngological drugs and preparations, initial encounter

Code EditsBilling

Medicare Code Editor checks that affect claim validity for T49.6X6A.

There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Coding GuidelinesGuidance

Underdosing refers to taking less of a medication than is prescribed by a provider or a manufacturer's instruction. Codes for underdosing should never be assigned as principal or first-listed codes. If a patient has a relapse or exacerbation of the medical condition for which the drug is prescribed because of the reduction in dose, then the medical condition itself should be coded.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinorlaryngological and dental drugs (T49). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ029
Underdosing of drugs and medicaments, initial encounter
Default principal diagnosis: inpatient No · outpatient No

Clinical InformationClinical

  • Tyrothricin

    a polypeptide antibiotic mixture obtained from bacillus brevis. it consists of a mixture of three tyrocidines (60%) and several gramicidins (20%) and is very toxic to blood, liver, kidneys, meninges, and the olfactory apparatus. it is used topically.

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
Alkaline antiseptic solution (aromatic)T49.6X1T49.6X2T49.6X3T49.6X4T49.6X5T49.6X6
AmbazoneT49.6X1T49.6X2T49.6X3T49.6X4T49.6X5T49.6X6
AmylmetacresolT49.6X1T49.6X2T49.6X3T49.6X4T49.6X5T49.6X6
BiclotymolT49.6X1T49.6X2T49.6X3T49.6X4T49.6X5T49.6X6
Bisdequalinium (salts) (diacetate)T49.6X1T49.6X2T49.6X3T49.6X4T49.6X5T49.6X6
CorbadrineT49.6X1T49.6X2T49.6X3T49.6X4T49.6X5T49.6X6
Dichlorobenzyl alcoholT49.6X1T49.6X2T49.6X3T49.6X4T49.6X5T49.6X6
Ear drug NECT49.6X1T49.6X2T49.6X3T49.6X4T49.6X5T49.6X6
Ear preparationsT49.6X1T49.6X2T49.6X3T49.6X4T49.6X5T49.6X6
ENT preparations (anti-infectives)T49.6X1T49.6X2T49.6X3T49.6X4T49.6X5T49.6X6
LevonordefrinT49.6X1T49.6X2T49.6X3T49.6X4T49.6X5T49.6X6
Lozenges (throat)T49.6X1T49.6X2T49.6X3T49.6X4T49.6X5T49.6X6
Mouthwash (antiseptic) (zinc chloride)T49.6X1T49.6X2T49.6X3T49.6X4T49.6X5T49.6X6
Nasal drug NECT49.6X1T49.6X2T49.6X3T49.6X4T49.6X5T49.6X6
Nose preparationsT49.6X1T49.6X2T49.6X3T49.6X4T49.6X5T49.6X6
Otorhinolaryngological drug NECT49.6X1T49.6X2T49.6X3T49.6X4T49.6X5T49.6X6
Thenoic acidT49.6X1T49.6X2T49.6X3T49.6X4T49.6X5T49.6X6
Throat drug NECT49.6X1T49.6X2T49.6X3T49.6X4T49.6X5T49.6X6
TyrothricinT49.6X1T49.6X2T49.6X3T49.6X4T49.6X5T49.6X6
Tyrothricin::ENT agentT49.6X1T49.6X2T49.6X3T49.6X4T49.6X5T49.6X6
Tyrothricin::ophthalmic preparationT49.6X1T49.6X2T49.6X3T49.6X4T49.6X5T49.6X6

Patient EducationClinical

Medication Errors

Medicines treat infectious diseases, prevent problems from chronic diseases, and ease pain. But medicines can also cause harmful reactions if not used correctly. Errors can happen in the hospital, at the health care provider's office, at the pharmacy, or at home. You can help prevent errors by:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T49.6X6A to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
No Map There is no ICD-9 equivalent for this code.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About T49.6X6AOverview

Is T49.6X6A (Underdosing of otorhinolaryngological drugs and preparations) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report underdosing of otorhinolaryngological drugs and preparations, initial encounter on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What does the 7th character A in T49.6X6A mean?

The final character A marks the initial encounter: use it while the patient is receiving active treatment for underdosing of otorhinolaryngological drugs and preparations, such as an emergency visit or first evaluation.

Can T49.6X6A be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because underdosing of otorhinolaryngological drugs and preparations, initial encounter describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.