2026 ICD-10-CM Diagnosis Code T49.4X6AUnderdosing of keratolytics, keratoplastics, and other hair treatment drugs and preparations, initial encounter

ICD-10-CM CodesS00–T88T36-T50T49

ICD-10-CM T49.4X6A
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

T49.4X6A is a billable ICD-10-CM diagnosis code for underdosing of keratolytics, keratoplastics, and other hair treatment drugs and preparations, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The code is not accepted as a principal diagnosis by the Medicare Code Editor. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Underdosing of drugs and medicaments, initial encounter.

Code Identity

ICD-10-CM Code
T49.4X6A
Billable Status
Yes — Valid for Submission
Code Describes
Underdosing of keratolytics, keratoplastics, and other hair treatment drugs and preparations, initial encounter
Short Description
Underdosing of keratolyt/keratplst/hair trmt drug, init
Parent Code
Underdosing of keratolytics, keratoplastics, and other hair treatment drugs and preparations

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT49Poisoning by, adverse effect of and underdosing of topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinorlaryngological and dental drugs
This CodeT49.4X6AUnderdosing of keratolytics, keratoplastics, and other hair treatment drugs and preparations, initial encounter

Code EditsBilling

Medicare Code Editor checks that affect claim validity for T49.4X6A.

There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Coding GuidelinesGuidance

Underdosing refers to taking less of a medication than is prescribed by a provider or a manufacturer's instruction. Codes for underdosing should never be assigned as principal or first-listed codes. If a patient has a relapse or exacerbation of the medical condition for which the drug is prescribed because of the reduction in dose, then the medical condition itself should be coded.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinorlaryngological and dental drugs (T49). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ029
Underdosing of drugs and medicaments, initial encounter
Default principal diagnosis: inpatient No · outpatient No

Clinical InformationClinical

  • Allantoin

    a urea hydantoin that is found in urine and plants and is used in dermatological preparations.
  • Anthralin

    an anthracene derivative that disrupts function and structure of mitochondria and is used for the treatment of dermatoses, especially psoriasis. it may cause folliculitis.
  • Capsaicin

    an alkylamide found in capsicum that acts at trpv cation channels.
  • Capsicum

    a plant genus of the family solanaceae. the hot peppers yield capsaicin, which activates vanilloid receptors. several varieties have sweet or pungent edible fruits that are used as vegetables when fresh and spices when the pods are dried.
  • Anacardic Acids

    a group of 6-alkyl salicylic acids that are found in anacardium and known for causing contact dermatitis.
  • Salicylates

    the salts or esters of salicylic acids, or salicylate esters of an organic acid. some of these have analgesic, antipyretic, and anti-inflammatory activities by inhibiting prostaglandin synthesis.
  • Salicylic Acid

    a compound obtained from the bark of the white willow and wintergreen leaves. it has bacteriostatic, fungicidal, and keratolytic actions.

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
AllantoinT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Alum (medicinal)T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Alum (medicinal)::nonmedicinal (ammonium) (potassium)T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
AnthralinT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
AntiseborrheicsT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Bleaching agent (medicinal)T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
ButantroneT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Cade oilT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
CapsicumT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Carbazochrome (salicylate) (sodium sulfonate)T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
ChlorothymolT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
ChloroxineT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
ChrysarobinT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
CollagenaseT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Corn curesT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
DepilatoryT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Desloughing agentT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Diachylon plasterT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Dimethylamine sulfateT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
DithranolT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
EuresolT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Flowers of sulfurT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Fumaric acidT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
HairT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Hair::dyeT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Hair::preparation NECT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
HemostypticT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
IchthyolT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Keratolytic drug NECT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Keratolytic drug NEC::anthraceneT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Keratoplastic NECT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Lassar's pasteT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
MonobenzoneT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Podophyllum (resin)T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Preparation, localT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Pyrithione zincT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
RubefacientT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Salicylic acidT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Salicylic acid::with benzoic acidT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Salicylic acid::congenersT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Salicylic acid::derivativeT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Salicylic acid::saltsT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Savin (oil)T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
SelsunT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Sulfur, sulfurated, sulfuric, sulfurous, sulfuryl (compounds NEC) (medicinal)T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Sulfur, sulfurated, sulfuric, sulfurous, sulfuryl (compounds NEC) (medicinal)::acidT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Sulfur, sulfurated, sulfuric, sulfurous, sulfuryl (compounds NEC) (medicinal)::dioxide (gas)T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Sulfur, sulfurated, sulfuric, sulfurous, sulfuryl (compounds NEC) (medicinal)::etherT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Sulfur, sulfurated, sulfuric, sulfurous, sulfuryl (compounds NEC) (medicinal)::hydrogenT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Sulfur, sulfurated, sulfuric, sulfurous, sulfuryl (compounds NEC) (medicinal)::medicinal (keratolytic) (ointment) NECT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Sulfur, sulfurated, sulfuric, sulfurous, sulfuryl (compounds NEC) (medicinal)::ointmentT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Sulfur, sulfurated, sulfuric, sulfurous, sulfuryl (compounds NEC) (medicinal)::pesticide (vapor)T49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Sulfur, sulfurated, sulfuric, sulfurous, sulfuryl (compounds NEC) (medicinal)::vapor NECT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
ThioglycolateT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
TioxoloneT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
TriacetoxyanthraceneT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
TrioxysalenT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
Vleminckx's solutionT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6
XenysalateT49.4X1T49.4X2T49.4X3T49.4X4T49.4X5T49.4X6

Patient EducationClinical

Medication Errors

Medicines treat infectious diseases, prevent problems from chronic diseases, and ease pain. But medicines can also cause harmful reactions if not used correctly. Errors can happen in the hospital, at the health care provider's office, at the pharmacy, or at home. You can help prevent errors by:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T49.4X6A to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
No Map There is no ICD-9 equivalent for this code.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About T49.4X6AOverview

Is T49.4X6A a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report underdosing of keratolytics, keratoplastics, and other hair treatment drugs and preparations, initial encounter on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What does the 7th character A in T49.4X6A mean?

The final character A marks the initial encounter: use it while the patient is receiving active treatment for underdosing of keratolytics, keratoplastics, and other hair treatment drugs and preparations, such as an emergency visit or first evaluation.

Can T49.4X6A be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because underdosing of keratolytics, keratoplastics, and other hair treatment drugs and preparations, initial encounter describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.