2027 ICD-10-CM Diagnosis Code T49.3X6AUnderdosing of emollients, demulcents and protectants, initial encounter

ICD-10-CM Codes›S00–T88›T36-T50›T49

ICD-10-CM T49.3X6A
CMSSource: CMS FY 2027 ICD-10-CM dataset · Effective Oct 1, 2026 – Sep 30, 2027

T49.3X6A is a billable ICD-10-CM diagnosis code for underdosing of emollients, demulcents and protectants, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2027 (October 1, 2026 through September 30, 2027) and groups to MS-DRG 951. The code is not accepted as a principal diagnosis by the Medicare Code Editor. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Underdosing of drugs and medicaments, initial encounter.

Code Identity

ICD-10-CM Code
T49.3X6A
Billable Status
Yes — Valid for Submission
Code Describes
Underdosing of emollients, demulcents and protectants, initial encounter
Short Description
Underdosing of emollients, demulcents and protectants, init
Parent Code
Underdosing of emollients, demulcents and protectants

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT49Poisoning by, adverse effect of and underdosing of topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinorlaryngological and dental drugs
This CodeT49.3X6AUnderdosing of emollients, demulcents and protectants, initial encounter

Code EditsBilling

Medicare Code Editor checks that affect claim validity for T49.3X6A.

There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Coding GuidelinesGuidance

Underdosing refers to taking less of a medication than is prescribed by a provider or a manufacturer's instruction. Codes for underdosing should never be assigned as principal or first-listed codes. If a patient has a relapse or exacerbation of the medical condition for which the drug is prescribed because of the reduction in dose, then the medical condition itself should be coded.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinorlaryngological and dental drugs (T49). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2027, published by CMS and the National Center for Health Statistics.

Instructional NotesGuidance

Instructions from the official ICD-10-CM Tabular List that apply to T49.3X6A: its own notes plus those printed at T49, block T36-T50, and Chapter 19. A note printed at a category, block or chapter applies to every code under it.

Includes

Further defines, or gives examples of, the content of the category.

From T49 Poisoning by, adverse effect of and underdosing of topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinorlaryngological and dental drugs applies to 180 codes
  • poisoning by, adverse effect of and underdosing of glucocorticoids, topically used
From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • adverse effect of correct substance properly administered
  • poisoning by overdose of substance
  • poisoning by wrong substance given or taken in error
  • underdosing by (inadvertently) (deliberately) taking less substance than prescribed or instructed

Excludes1

Not coded here: the excluded code is never reported together with this one, unless the two conditions are unrelated.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • toxic reaction to local anesthesia in pregnancy (O29.3-)

Excludes2

Not included here: the excluded condition is not part of this code, but a patient may have both, so both codes may be reported.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • abuse and dependence of psychoactive substances (F10-F19)
  • abuse of non-dependence-producing substances (F55.-)
  • immunodeficiency due to drugs (D84.821)
  • drug reaction and poisoning affecting newborn (P00-P96)
  • pathological drug intoxication (inebriation) (F10-F19)
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes

Code First

The underlying condition named in the note is sequenced before this code.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • for adverse effects, the nature of the adverse effect, such as:
  • adverse effect NOS (T88.7)
  • aspirin gastritis (K29.-)
  • blood disorders (D56-D76)
  • contact dermatitis (L23-L25)
  • dermatitis due to substances taken internally (L27.-)
  • nephropathy (N14.0-N14.2)

Use Additional Code

Add a second code, after this one, to fully describe the condition.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • code(s) to specify:
  • manifestations of poisoning
  • underdosing or failure in dosage during medical and surgical care (Y63.6, Y63.8-Y63.9)
  • underdosing of medication regimen (Z91.12-, Z91.13-)
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes
  • code to identify any retained foreign body, if applicable (Z18.-)

Notes

General instructions on how these codes are used.

From Block T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances applies to 3,186 codes
  • The drug giving rise to the adverse effect should be identified by use of codes from categories T36-T50 with fifth or sixth character 5.
From Chapter 19 (S00-T88) Injury, poisoning and certain other consequences of external causes applies to 41,187 codes
  • Use secondary code(s) from Chapter 20, External causes of morbidity, to indicate cause of injury. Codes within the T section that include the external cause do not require an additional external cause code
  • The chapter uses the S-section for coding different types of injuries related to single body regions and the T-section to cover injuries to unspecified body regions as well as poisoning and certain other consequences of external causes.

7th Character

Every code in the category takes a 7th character from the listed values, with the placeholder X filling any empty positions before it.

From T49 Poisoning by, adverse effect of and underdosing of topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinorlaryngological and dental drugs applies to 180 codes
  • The appropriate 7th character is to be added to each code from category T49
  • Ainitial encounter this code
  • Dsubsequent encounter
  • Ssequela

Source: CMS ICD-10-CM Tabular List. How to read instructional notes.

Referenced in Other NotesGuidance

Instructional notes printed at other codes that name T49.3X6A, its category, or a range that includes it.

Excludes1 1

These codes carry an Excludes1 note naming T49.3X6A: they are not reported together with it, unless the two conditions are unrelated.

  • T38.0 Poisoning by, adverse effect of and underdosing of glucocorticoids and synthetic analogues
    glucocorticoids, topically used (T49.-) names T49.-, which includes this code

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ029
Underdosing of drugs and medicaments, initial encounter
Default principal diagnosis: inpatient No · outpatient No

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
Acetic::acid::with sodium acetate (ointment)T49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Acrylic resinT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
AllylthioureaT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Aluminium, aluminum::ointment (surgical) (topical)T49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Aluminium, aluminum::topical NECT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Aminobenzoic acid (-p)T49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Arachis oilT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Barrier creamT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
BentoniteT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
BenzophenonesT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Betula oilT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Calamine (lotion)T49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
CarbowaxT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Cellulose::nitrates (topical)T49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Chlordiethyl benzamideT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Cold creamT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
CollodionT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Colophony adhesiveT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Corn starchT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Cornhusker's lotionT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Cottonseed oilT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Cyanoacrylate adhesiveT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Demulcent (external)T49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Demulcent (external)::specified NECT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Diethyl::toluamide (nonmedicinal)::medicinalT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Dimethyl::phthlateT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Emollient NECT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Filtering creamT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Flaxseed (medicinal)T49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
HomosalateT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Hydrophilic lotionT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Hydrous wool fatT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
LanolinT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Liquid::petrolatum::topicalT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
MecrilateT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
MeladininT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Melanizing agentsT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
MeloxineT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Methoxa-DomeT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
MexenoneT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Mineral::oil (laxative) (medicinal)::topicalT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Nutmeg oil (liniment)T49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Octafonium (chloride)T49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Oil (of)::wintergreen (bitter) NECT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Oily preparation (for skin)T49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Ointment NECT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
OxsoralenT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
PABAT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
PadimateT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Para-aminobenzoic acidT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Peanut oil (emulsion) NEC::topicalT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
PetrolatumT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Petrolatum::hydrophilicT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Petrolatum::liquid::topicalT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Petrolatum::red veterinaryT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Petrolatum::whiteT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Phenyl::salicylateT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Plaster dressingT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Plastic dressingT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Polyethylene adhesiveT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Protectant, skin NECT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
PyroxylinT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Rose water ointmentT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Salicylate NEC::methylT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
SalolT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Silicone NEC::medicinalT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Solar lotionT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
SulisobenzoneT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Sweet oil (birch)T49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Talc powderT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
TalcumT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
ThiosinamineT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Titanium (compounds) (vapor)::dioxideT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Titanium (compounds) (vapor)::ointmentT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Titanium (compounds) (vapor)::oxideT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
TrimethylpsoralenT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
TrisoralenT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Ultraviolet light protectantT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Unna's bootT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
VaselineT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Wintergreen (oil)T49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Wool fat (hydrous)T49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
XanthotoxinT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Zinc (compounds) (fumes) (vapor) NEC::gelatinT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Zinc (compounds) (fumes) (vapor) NEC::oxideT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Zinc (compounds) (fumes) (vapor) NEC::oxide::plasterT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Zinc (compounds) (fumes) (vapor) NEC::stearateT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6

Patient EducationClinical

Medication Errors

Medicines treat infectious diseases, prevent problems from chronic diseases, and ease pain. But medicines can also cause harmful reactions if not used correctly. Errors can happen in the hospital, at the health care provider's office, at the pharmacy, or at home. You can help prevent errors by:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T49.3X6A to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
No Map There is no ICD-9 equivalent for this code.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2026No changes
FY 2027CurrentCurrent code set, no changesEffective October 1, 2026 through September 30, 2027.

Questions About T49.3X6AOverview

Is T49.3X6A (Underdosing of emollients, demulcents and protectants) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report underdosing of emollients, demulcents and protectants, initial encounter on HIPAA-covered claims from October 1, 2026 through September 30, 2027.

What does the 7th character A in T49.3X6A mean?

The final character A marks the initial encounter: use it while the patient is receiving active treatment for underdosing of emollients, demulcents and protectants, such as an emergency visit or first evaluation.

What MS-DRG does T49.3X6A group to?

On inpatient claims, underdosing of emollients, demulcents and protectants, initial encounter maps to MS-DRG 951 (other Factors Influencing Health Status), which carries a relative weight of 0.5574. Higher weights mean higher Medicare reimbursement.

Can T49.3X6A be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because underdosing of emollients, demulcents and protectants, initial encounter describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.

Can T49.3X6A be reported with a code from O29.3?

Not as a rule. The Excludes1 note at block T36-T50, which applies to T49.3X6A, lists "toxic reaction to local anesthesia in pregnancy (O29.3-)". An Excludes1 note means the excluded code is never reported together with this one; the only exception is when the two conditions are unrelated to each other (Official Guidelines, Section I.A.12.a).