2026 ICD-10-CM Diagnosis Code T49.3X4APoisoning by emollients, demulcents and protectants, undetermined, initial encounter

ICD-10-CM CodesS00–T88T36-T50T49

ICD-10-CM T49.3X4A
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

T49.3X4A is a billable ICD-10-CM diagnosis code for poisoning by emollients, demulcents and protectants, undetermined, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 917 through 918. Coders also document this condition as foreign body granuloma of muscle. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under External cause codes: intent of injury, undetermined; External cause codes: poisoning by drug; and Poisoning by drugs, initial encounter.

Code Identity

ICD-10-CM Code
T49.3X4A
Billable Status
Yes — Valid for Submission
Code Describes
Poisoning by emollients, demulcents and protectants, undetermined, initial encounter
Short Description
Poisoning by emollients, demulcents and protect, undet, init
Parent Code
Poisoning by emollients, demulcents and protectants, undetermined

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT49Poisoning by, adverse effect of and underdosing of topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinorlaryngological and dental drugs
This CodeT49.3X4APoisoning by emollients, demulcents and protectants, undetermined, initial encounter

Approximate SynonymsGuidance

Alternate terms and clinical phrases that map to this code.

  • Foreign body granuloma of muscle
  • Nodule in muscle
  • Nodule of skin of abdomen
  • Nodule of umbilical structure
  • Sarcoidal granuloma of skin
  • Talc granuloma of muscle
  • Talc granuloma of skin
  • Talc granuloma of umbilicus
  • Umbilical granuloma

Coding GuidelinesGuidance

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined). If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinorlaryngological and dental drugs (T49). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR EXT023
External cause codes: intent of injury, undetermined
Default principal diagnosis: inpatient No · outpatient No
CCSR EXT014
External cause codes: poisoning by drug
Default principal diagnosis: inpatient No · outpatient No
CCSR INJ022
Poisoning by drugs, initial encounter
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Umbilical Granuloma

    excessive granulation tissue at the base of the umbilicus after separation.
  • Foreign Body Granuloma of Muscle

    an inflammatory lesion in the muscle comprised of epithelioid histiocytes and chronic inflammation that is caused by the presence of extraneous material .

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
Acrylic resinT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
AllylthioureaT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Aminobenzoic acid (-p)T49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Arachis oilT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Arachis oil::catharticT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Barrier creamT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
BentoniteT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
BenzophenonesT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Betula oilT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Calamine (lotion)T49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
CarbowaxT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Chlordiethyl benzamideT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Cold creamT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
CollodionT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Colophony adhesiveT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Corn starchT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Cornhusker's lotionT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Cottonseed oilT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Cyanoacrylate adhesiveT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Demulcent (external)T49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Demulcent (external)::specified NECT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Emollient NECT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Filtering creamT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Flaxseed (medicinal)T49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
HomosalateT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Hydrophilic lotionT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Hydrous wool fatT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
LanolinT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
MecrilateT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
MeladininT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Melanizing agentsT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
MeloxineT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Methoxa-DomeT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
MexenoneT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Nutmeg oil (liniment)T49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Octafonium (chloride)T49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Oily preparation (for skin)T49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Ointment NECT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
OxsoralenT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
PABAT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
PadimateT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Para-aminobenzoic acidT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
PetrolatumT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Petrolatum::hydrophilicT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Petrolatum::liquidT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Petrolatum::liquid::topicalT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Petrolatum::nonmedicinalT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Petrolatum::red veterinaryT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Petrolatum::whiteT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Plaster dressingT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Plastic dressingT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Polyethylene adhesiveT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Protectant, skin NECT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
PyroxylinT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Rose water ointmentT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
SalolT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Solar lotionT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
SulisobenzoneT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Sweet oil (birch)T49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Talc powderT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
TalcumT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
ThiosinamineT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
TrimethylpsoralenT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
TrisoralenT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Ultraviolet light protectantT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Unna's bootT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
VaselineT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Wintergreen (oil)T49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
Wool fat (hydrous)T49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6
XanthotoxinT49.3X1T49.3X2T49.3X3T49.3X4T49.3X5T49.3X6

Patient EducationClinical

Poisoning

A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it, or absorb it through your skin. Any substance can be poisonous if too much is taken. Poisons can include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T49.3X4A to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
976.3 Pois-emol/demul/protect
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
E980.4 Undet pois-med agnt NEC
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About T49.3X4AOverview

Is T49.3X4A a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report poisoning by emollients, demulcents and protectants, undetermined, initial encounter on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What does the 7th character A in T49.3X4A mean?

The final character A marks the initial encounter: use it while the patient is receiving active treatment for poisoning by emollients, demulcents and protectants, undetermined, such as an emergency visit or first evaluation.

What MS-DRG does T49.3X4A group to?

When poisoning by emollients, demulcents and protectants, undetermined, initial encounter is the principal diagnosis on an inpatient stay, it groups to MS-DRG 917, 918, with relative weights from 0.8571 to 1.5684 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of T49.3X4A?

Under the General Equivalence Mappings, poisoning by emollients, demulcents and protectants, undetermined, initial encounter converts to ICD-9-CM 976.3 (pois-emol/demul/protect) and E980.4 (undet pois-med agnt NEC). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.