2026 ICD-10-CM Diagnosis Code T48.5X6AUnderdosing of other anti-common-cold drugs, initial encounter

ICD-10-CM CodesS00–T88T36-T50T48

ICD-10-CM T48.5X6A
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

T48.5X6A is a billable ICD-10-CM diagnosis code for underdosing of other anti-common-cold drugs, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The code is not accepted as a principal diagnosis by the Medicare Code Editor. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Underdosing of drugs and medicaments, initial encounter.

Code Identity

ICD-10-CM Code
T48.5X6A
Billable Status
Yes — Valid for Submission
Code Describes
Underdosing of other anti-common-cold drugs, initial encounter
Short Description
Underdosing of other anti-common-cold drugs, init encntr
Parent Code
Underdosing of other anti-common-cold drugs

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT48Poisoning by, adverse effect of and underdosing of agents primarily acting on smooth and skeletal muscles and the respiratory system
This CodeT48.5X6AUnderdosing of other anti-common-cold drugs, initial encounter

Code EditsBilling

Medicare Code Editor checks that affect claim validity for T48.5X6A.

There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Coding GuidelinesGuidance

Underdosing refers to taking less of a medication than is prescribed by a provider or a manufacturer's instruction. Codes for underdosing should never be assigned as principal or first-listed codes. If a patient has a relapse or exacerbation of the medical condition for which the drug is prescribed because of the reduction in dose, then the medical condition itself should be coded.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of agents primarily acting on smooth and skeletal muscles and the respiratory system (T48). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ029
Underdosing of drugs and medicaments, initial encounter
Default principal diagnosis: inpatient No · outpatient No

Clinical InformationClinical

  • Menthol

    a monoterpene cyclohexanol produced from mint oils.
  • Naphazoline

    an adrenergic vasoconstrictor agent used as a decongestant.
  • Oxymetazoline

    a direct acting sympathomimetic used as a vasoconstrictor to relieve nasal congestion. (from martindale, the extra pharmacopoeia, 30th ed, p1251)

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
Amidefrine mesilateT48.5X1T48.5X2T48.5X3T48.5X4T48.5X5T48.5X6
Anti-common-cold drug NECT48.5X1T48.5X2T48.5X3T48.5X4T48.5X5T48.5X6
APCT48.5X1T48.5X2T48.5X3T48.5X4T48.5X5T48.5X6
Benzoin (tincture)T48.5X1T48.5X2T48.5X3T48.5X4T48.5X5T48.5X6
CinnamedrineT48.5X1T48.5X2T48.5X3T48.5X4T48.5X5T48.5X6
ContacT48.5X1T48.5X2T48.5X3T48.5X4T48.5X5T48.5X6
Decongestant, nasal (mucosa)T48.5X1T48.5X2T48.5X3T48.5X4T48.5X5T48.5X6
Decongestant, nasal (mucosa)::combinationT48.5X1T48.5X2T48.5X3T48.5X4T48.5X5T48.5X6
FenoxazolineT48.5X1T48.5X2T48.5X3T48.5X4T48.5X5T48.5X6
IndanazolineT48.5X1T48.5X2T48.5X3T48.5X4T48.5X5T48.5X6
MentholT48.5X1T48.5X2T48.5X3T48.5X4T48.5X5T48.5X6
MetizolineT48.5X1T48.5X2T48.5X3T48.5X4T48.5X5T48.5X6
NaphazolineT48.5X1T48.5X2T48.5X3T48.5X4T48.5X5T48.5X6
OxymetazolineT48.5X1T48.5X2T48.5X3T48.5X4T48.5X5T48.5X6
PropylhexedrineT48.5X1T48.5X2T48.5X3T48.5X4T48.5X5T48.5X6
TramazolineT48.5X1T48.5X2T48.5X3T48.5X4T48.5X5T48.5X6
TuaminoheptaneT48.5X1T48.5X2T48.5X3T48.5X4T48.5X5T48.5X6
TymazolineT48.5X1T48.5X2T48.5X3T48.5X4T48.5X5T48.5X6
XylometazolineT48.5X1T48.5X2T48.5X3T48.5X4T48.5X5T48.5X6

Patient EducationClinical

Cold and Cough Medicines

Cold and cough medicines can help relieve symptoms of a common cold. The symptoms of a cold can include a sore throat, stuffy or runny nose, sneezing, and coughing.

The full article covers:

  • What are cold and cough medicines?
  • What are the different types of cold and cough medicines?
  • What do I need to know about taking cold and cough medicines?
  • What else can I do to feel better for a cold or cough?

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T48.5X6A to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
No Map There is no ICD-9 equivalent for this code.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About T48.5X6AOverview

Is T48.5X6A (Underdosing of other anti-common-cold drugs) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report underdosing of other anti-common-cold drugs, initial encounter on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What does the 7th character A in T48.5X6A mean?

The final character A marks the initial encounter: use it while the patient is receiving active treatment for underdosing of other anti-common-cold drugs, such as an emergency visit or first evaluation.

Can T48.5X6A be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because underdosing of other anti-common-cold drugs, initial encounter describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.