2026 ICD-10-CM Diagnosis Code T48.3X6AUnderdosing of antitussives, initial encounter

ICD-10-CM CodesS00–T88T36-T50T48

ICD-10-CM T48.3X6A
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

T48.3X6A is a billable ICD-10-CM diagnosis code for underdosing of antitussives, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The code is not accepted as a principal diagnosis by the Medicare Code Editor. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Underdosing of drugs and medicaments, initial encounter.

Code Identity

ICD-10-CM Code
T48.3X6A
Billable Status
Yes — Valid for Submission
Code Describes
Underdosing of antitussives, initial encounter
Short Description
Underdosing of antitussives, initial encounter
Same as the full description in the CMS dataset.
Parent Code
Underdosing of antitussives

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT48Poisoning by, adverse effect of and underdosing of agents primarily acting on smooth and skeletal muscles and the respiratory system
This CodeT48.3X6AUnderdosing of antitussives, initial encounter

Code EditsBilling

Medicare Code Editor checks that affect claim validity for T48.3X6A.

There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Coding GuidelinesGuidance

Underdosing refers to taking less of a medication than is prescribed by a provider or a manufacturer's instruction. Codes for underdosing should never be assigned as principal or first-listed codes. If a patient has a relapse or exacerbation of the medical condition for which the drug is prescribed because of the reduction in dose, then the medical condition itself should be coded.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of agents primarily acting on smooth and skeletal muscles and the respiratory system (T48). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ029
Underdosing of drugs and medicaments, initial encounter
Default principal diagnosis: inpatient No · outpatient No

Clinical InformationClinical

  • Dextromethorphan

    methyl analog of dextrorphan that shows high affinity binding to several regions of the brain, including the medullary cough center. this compound is an nmda receptor antagonist (receptors, n-methyl-d-aspartate) and acts as a non-competitive channel blocker. it is one of the widely used antitussives, and is also used to study the involvement of glutamate receptors in neurotoxicity.
  • Noscapine

    a naturally occurring opium alkaloid that is a centrally acting antitussive agent.

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
Antitussive NECT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
Antitussive NEC::codeine mixtureT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
Antitussive NEC::opiateT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
BenproperineT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
BenzonatateT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
Bibenzonium bromideT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
ButamirateT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
CarbetapentaneT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
ChlophedianolT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
ClobutinolT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
ClofedanolT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
CloperastineT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
ClophedianolT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
DextromethorphanT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
Dibunate sodiumT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
DimemorfanT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
DimethoxanateT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
DropropizineT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
FedrilateT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
FominobenT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
Isoaminile (citrate)T48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
LevdropropizineT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
MethorateT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
NarcotineT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
NectadonT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
NoscapineT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
Oxeladin (citrate)T48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
OxolamineT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
PentoxyverineT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
PholcodineT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
PicoperineT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
PipazetateT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
PiperidioneT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
PrenoxdiazineT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
RomilarT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
TessalonT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
ThebaconT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
TipepidineT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6
ZipeprolT48.3X1T48.3X2T48.3X3T48.3X4T48.3X5T48.3X6

Patient EducationClinical

Medication Errors

Medicines treat infectious diseases, prevent problems from chronic diseases, and ease pain. But medicines can also cause harmful reactions if not used correctly. Errors can happen in the hospital, at the health care provider's office, at the pharmacy, or at home. You can help prevent errors by:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T48.3X6A to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
No Map There is no ICD-9 equivalent for this code.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About T48.3X6AOverview

Is T48.3X6A (Underdosing of antitussives) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report underdosing of antitussives, initial encounter on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What does the 7th character A in T48.3X6A mean?

The final character A marks the initial encounter: use it while the patient is receiving active treatment for underdosing of antitussives, such as an emergency visit or first evaluation.

Can T48.3X6A be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because underdosing of antitussives, initial encounter describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.