2026 ICD-10-CM Diagnosis Code T48.1X4APoisoning by skeletal muscle relaxants [neuromuscular blocking agents], undetermined, initial encounter

ICD-10-CM CodesS00–T88T36-T50T48

ICD-10-CM T48.1X4A
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

T48.1X4A is a billable ICD-10-CM diagnosis code for poisoning by skeletal muscle relaxants [neuromuscular blocking agents], undetermined, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 917 through 918. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under External cause codes: intent of injury, undetermined; External cause codes: poisoning by drug; and Poisoning by drugs, initial encounter.

Code Identity

ICD-10-CM Code
T48.1X4A
Billable Status
Yes — Valid for Submission
Code Describes
Poisoning by skeletal muscle relaxants [neuromuscular blocking agents], undetermined, initial encounter
Short Description
Poisoning by skeletal muscle relaxants, undetermined, init
Parent Code
Poisoning by skeletal muscle relaxants [neuromuscular blocking agents], undetermined

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT48Poisoning by, adverse effect of and underdosing of agents primarily acting on smooth and skeletal muscles and the respiratory system
This CodeT48.1X4APoisoning by skeletal muscle relaxants [neuromuscular blocking agents], undetermined, initial encounter

Coding GuidelinesGuidance

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined). If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of agents primarily acting on smooth and skeletal muscles and the respiratory system (T48). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR EXT023
External cause codes: intent of injury, undetermined
Default principal diagnosis: inpatient No · outpatient No
CCSR EXT014
External cause codes: poisoning by drug
Default principal diagnosis: inpatient No · outpatient No
CCSR INJ022
Poisoning by drugs, initial encounter
Default principal diagnosis: inpatient Yes · outpatient Yes

Clinical InformationClinical

  • Succinylcholine

    a quaternary skeletal muscle relaxant usually used in the form of its bromide, chloride, or iodide. it is a depolarizing relaxant, acting in about 30 seconds and with a duration of effect averaging three to five minutes. succinylcholine is used in surgical, anesthetic, and other procedures in which a brief period of muscle relaxation is called for.
  • Vecuronium Bromide

    monoquaternary homolog of pancuronium. a non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. its lack of significant cardiovascular effects and lack of dependence on good kidney function for elimination as well as its short duration of action and easy reversibility provide advantages over, or alternatives to, other established neuromuscular blocking agents.

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
Aclatonium napadisilateT48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
Alcuronium (chloride)T48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
Atracurium besilateT48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
Carbolonium (bromide)T48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
Curare, curarineT48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
CyclobenzaprineT48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
Decamethonium (bromide)T48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
Dimethyltubocurarinium chlorideT48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
Fazadinium bromideT48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
FlaxedilT48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
Gallamine (triethiodide)T48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
Hexafluorenium bromideT48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
Hexafluronium (bromide)T48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
HexanuoreniumT48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
Hexcarbacholine bromideT48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
LaudexiumT48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
Mivacurium chlorideT48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
Myoneural blocking agentsT48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
Neuromuscular blocking drugT48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
Pancuronium (bromide)T48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
Relaxant, muscleT48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
Relaxant, muscle::anestheticT48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
Relaxant, muscle::central nervous systemT48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
Relaxant, muscle::skeletal NECT48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
Relaxant, muscle::smooth NECT48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
Skeletal muscle relaxantsT48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
SuccinylcholineT48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
Suxamethonium (chloride)T48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
Suxethonium (chloride)T48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
TubocurareT48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
Tubocurarine (chloride)T48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
UrariT48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
Vecuronium bromideT48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6
WooraliT48.1X1T48.1X2T48.1X3T48.1X4T48.1X5T48.1X6

Patient EducationClinical

Poisoning

A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it, or absorb it through your skin. Any substance can be poisonous if too much is taken. Poisons can include:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T48.1X4A to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
975.2 Pois-skelet muscle relax
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.
ICD-9-CM
E980.4 Undet pois-med agnt NEC
ApproximateCombination The match is approximate, and more than one code can be needed to describe the source diagnosis. Confirm with contextual judgment.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About T48.1X4AOverview

Is T48.1X4A a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report poisoning by skeletal muscle relaxants [neuromuscular blocking agents], undetermined, initial encounter on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What does the 7th character A in T48.1X4A mean?

The final character A marks the initial encounter: use it while the patient is receiving active treatment for poisoning by skeletal muscle relaxants [neuromuscular blocking agents], undetermined, such as an emergency visit or first evaluation.

What MS-DRG does T48.1X4A group to?

When poisoning by skeletal muscle relaxants [neuromuscular blocking agents], undetermined, initial encounter is the principal diagnosis on an inpatient stay, it groups to MS-DRG 917, 918, with relative weights from 0.8571 to 1.5684 depending on complications. Higher weights mean higher Medicare reimbursement.

What is the ICD-9 equivalent of T48.1X4A?

Under the General Equivalence Mappings, poisoning by skeletal muscle relaxants [neuromuscular blocking agents], undetermined, initial encounter converts to ICD-9-CM 975.2 (pois-skelet muscle relax) and E980.4 (undet pois-med agnt NEC). The mapping is approximate, so confirm the match fits the documentation.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.