2026 ICD-10-CM Diagnosis Code T48.0X4APoisoning by oxytocic drugs, undetermined, initial encounter
T48.0X4A is a billable ICD-10-CM diagnosis code for poisoning by oxytocic drugs, undetermined, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 917 through 918. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under External cause codes: intent of injury, undetermined; External cause codes: poisoning by drug; and Poisoning by drugs, initial encounter.
Code Identity
Code Classification
Coding GuidelinesGuidance
When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined). If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.
The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of agents primarily acting on smooth and skeletal muscles and the respiratory system (T48). Use the following options for the applicable episode of care:
- A - initial encounter
- D - subsequent encounter
- S - sequela
Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Carboprost
a nonsteroidal abortifacient agent that is effective in both the first and second trimesters of pregnancy.Dinoprost
a naturally occurring prostaglandin that has oxytocic, luteolytic, and abortifacient activities. due to its vasocontractile properties, the compound has a variety of other biological actions.Dinoprostone
the most common and most biologically active of the mammalian prostaglandins. it exhibits most biological activities characteristic of prostaglandins and has been used extensively as an oxytocic agent. the compound also displays a protective effect on the intestinal mucosa.Ergonovine
an ergot alkaloid (ergot alkaloids) with uterine and vascular smooth muscle contractile properties.Methylergonovine
a homolog of ergonovine containing one more ch2 group. (merck index, 11th ed)Cytochrome P-450 CYP2D6
a cytochrome p450 enzyme that catalyzes the hydroxylation of many drugs and environmental chemicals, such as debrisoquine; adrenergic receptor antagonists; and tricyclic antidepressants. this enzyme is deficient in up to 10 percent of the caucasian population.Sparteine
a quinolizidine alkaloid isolated from several fabaceae including lupinus; spartium; and cytisus. it has been used as an oxytocic and an anti-arrhythmia agent. it has also been of interest as an indicator of cyp2d6 genotype.
Table of Drugs and ChemicalsClinical
Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.
Patient EducationClinical
Poisoning
A poison is any substance that is harmful to your body. You might swallow it, inhale it, inject it, or absorb it through your skin. Any substance can be poisonous if too much is taken. Poisons can include:
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert T48.0X4A to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About T48.0X4AOverview
Is T48.0X4A (Poisoning by oxytocic drugs, undetermined) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report poisoning by oxytocic drugs, undetermined, initial encounter on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What does the 7th character A in T48.0X4A mean?
The final character A marks the initial encounter: use it while the patient is receiving active treatment for poisoning by oxytocic drugs, undetermined, such as an emergency visit or first evaluation.
What MS-DRG does T48.0X4A group to?
When poisoning by oxytocic drugs, undetermined, initial encounter is the principal diagnosis on an inpatient stay, it groups to MS-DRG 917, 918, with relative weights from 0.8571 to 1.5684 depending on complications. Higher weights mean higher Medicare reimbursement.
What is the ICD-9 equivalent of T48.0X4A?
Under the General Equivalence Mappings, poisoning by oxytocic drugs, undetermined, initial encounter converts to ICD-9-CM 975.0 (poisoning-oxytocic agent) and E980.4 (undet pois-med agnt NEC). The mapping is approximate, so confirm the match fits the documentation.
Footnotes
[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.
