2026 ICD-10-CM Diagnosis Code T47.5X6AUnderdosing of digestants, initial encounter

ICD-10-CM CodesS00–T88T36-T50T47

ICD-10-CM T47.5X6A
CMSSource: CMS FY 2026 ICD-10-CM dataset · Effective Oct 1, 2025 – Sep 30, 2026

T47.5X6A is a billable ICD-10-CM diagnosis code for underdosing of digestants, initial encounter. The 7th character A marks it as an initial encounter code, used while the patient is receiving active treatment. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026). The code is not accepted as a principal diagnosis by the Medicare Code Editor. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Underdosing of drugs and medicaments, initial encounter.

Code Identity

ICD-10-CM Code
T47.5X6A
Billable Status
Yes — Valid for Submission
Code Describes
Underdosing of digestants, initial encounter
Short Description
Underdosing of digestants, initial encounter
Same as the full description in the CMS dataset.
Parent Code
Underdosing of digestants

Code Classification

ChapterS00–T88Injury, poisoning and certain other consequences of external causes
SectionT36-T50Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
CategoryT47Poisoning by, adverse effect of and underdosing of agents primarily affecting the gastrointestinal system
This CodeT47.5X6AUnderdosing of digestants, initial encounter

Code EditsBilling

Medicare Code Editor checks that affect claim validity for T47.5X6A.

There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Coding GuidelinesGuidance

Underdosing refers to taking less of a medication than is prescribed by a provider or a manufacturer's instruction. Codes for underdosing should never be assigned as principal or first-listed codes. If a patient has a relapse or exacerbation of the medical condition for which the drug is prescribed because of the reduction in dose, then the medical condition itself should be coded.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of agents primarily affecting the gastrointestinal system (T47). Use the following options for the applicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.

Clinical ClassificationClinical

AHRQ’s CCSR groups this code into broader clinical categories.

CCSR INJ029
Underdosing of drugs and medicaments, initial encounter
Default principal diagnosis: inpatient No · outpatient No

Clinical InformationClinical

  • Betaine

    a naturally occurring compound that has been of interest for its role in osmoregulation. as a drug, betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria. betaine has also been used in the treatment of liver disorders, for hyperkalemia, for homocystinuria, and for gastrointestinal disturbances. (from martindale, the extra pharmacopoeia, 30th ed, p1341)
  • Betaine-Aldehyde Dehydrogenase

    an nad+ dependent enzyme that catalyzes the oxidation of betain aldehyde to betaine.
  • Betaine-Homocysteine S-Methyltransferase

    a zinc metalloenzyme that catalyzes the transfer of a methyl group from betaine to homocysteine to produce dimethylglycine and methionine, respectively. this enzyme is a member of a family of zinc-dependent methyltransferases that use thiols or selenols as methyl acceptors.
  • Chenodeoxycholic Acid

    a bile acid, usually conjugated with either glycine or taurine. it acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed by the small intestine. it is used as cholagogue, a choleretic laxative, and to prevent or dissolve gallstones.
  • Cholic Acid

    a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. it facilitates fat absorption and cholesterol excretion.
  • Cholic Acids

    the 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholanic acid family of bile acids in man, usually conjugated with glycine or taurine. they act as detergents to solubilize fats for intestinal absorption, are reabsorbed by the small intestine, and are used as cholagogues and choleretics.
  • Citric Acid

    a key intermediate in metabolism. it is an acid compound found in citrus fruits. the salts of citric acid (citrates) can be used as anticoagulants due to their calcium chelating ability.
  • Citric Acid Cycle

    a series of oxidative reactions in the breakdown of acetyl units derived from glucose; fatty acids; or amino acids by means of tricarboxylic acid intermediates. the end products are carbon dioxide, water, and energy in the form of phosphate bonds.
  • Dehydrocholic Acid

    a semisynthetic bile acid made from cholic acid. it is used as a cholagogue, hydrocholeretic, diuretic, and as a diagnostic aid.
  • Glutamate Decarboxylase

    a pyridoxal-phosphate protein that catalyzes the alpha-decarboxylation of l-glutamic acid to form gamma-aminobutyric acid and carbon dioxide. the enzyme is found in bacteria and in invertebrate and vertebrate nervous systems. it is the rate-limiting enzyme in determining gamma-aminobutyric acid levels in normal nervous tissues. the brain enzyme also acts on l-cysteate, l-cysteine sulfinate, and l-aspartate. ec 4.1.1.15.
  • Glutamates

    derivatives of glutamic acid. included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the 2-aminopentanedioic acid structure.
  • Glutamic Acid

    a non-essential amino acid naturally occurring in the l-form. glutamic acid is the most common excitatory neurotransmitter in the central nervous system.
  • Plasminogen

    precursor of plasmin (fibrinolysin). it is a single-chain beta-globulin of molecular weight 80-90,000 found mostly in association with fibrinogen in plasma; plasminogen activators change it to fibrinolysin. it is used in wound debriding and has been investigated as a thrombolytic agent.
  • RNA, Transfer, Glu

    a transfer rna which is specific for carrying glutamic acid to sites on the ribosomes in preparation for protein synthesis.
  • Pancreatin

    a mammalian pancreatic extract composed of enzymes with protease, amylase and lipase activities. it is used as a digestant in pancreatic malfunction.
  • Pancrelipase

    a preparation of hog pancreatic enzymes standardized for lipase content.
  • Coronavirus Papain-Like Proteases

    papain-like proteases that occur in species of coronaviridae. some species have more than one papain-like protease gene.
  • Papain

    a proteolytic enzyme obtained from carica papaya. it is also the name used for a purified mixture of papain and chymopapain that is used as a topical enzymatic debriding agent. ec 3.4.22.2.

Table of Drugs and ChemicalsClinical

Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.

SubstanceAccidentalSelf-harmAssaultUndeter­minedAdverse
Effect
Under­dosing
AmylaseT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Anise oilT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
AntiflatulentT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
b-galactosidaseT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
BetaineT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Bile saltsT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
CarminativeT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Chenodeoxycholic acidT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
ChenodiolT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
CholagoguesT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
CholereticT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Cholic acidT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Citric acidT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Cytochrome CT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
DecholinT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Dehydrocholic acidT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
DiastaseT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Digestant NECT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
DillT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
ElastaseT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
FlorantyroneT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
b-GalactosidaseT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Gastric enzymesT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
GentianT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Gentian::violetT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
GingerT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Ginger::JamaicaT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Glutamic acidT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
LipancreatinT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Ox bile extractT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
PancreatinT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
PancrelipaseT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
PapainT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Papain::digestantT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Peppermint (oil)T47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
PepsinT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
Pepsin::digestantT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
PhenylpropanolT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
ProteaseT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6
TilactaseT47.5X1T47.5X2T47.5X3T47.5X4T47.5X5T47.5X6

Patient EducationClinical

Medication Errors

Medicines treat infectious diseases, prevent problems from chronic diseases, and ease pain. But medicines can also cause harmful reactions if not used correctly. Errors can happen in the hospital, at the health care provider's office, at the pharmacy, or at home. You can help prevent errors by:

Read the full article at MedlinePlus

Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.

Convert T47.5X6A to ICD-9-CMHistory

The closest ICD-9-CM equivalents under the General Equivalence Mappings.

ICD-9-CM
No Map There is no ICD-9 equivalent for this code.

Code HistoryHistory

FY 2016AddedAdded to the ICD-10-CM code setEffective October 1, 2015, the first year of ICD-10-CM.
FY 2017–2025No changes
FY 2026CurrentCurrent code set, no changesEffective October 1, 2025 through September 30, 2026.

Questions About T47.5X6AOverview

Is T47.5X6A (Underdosing of digestants) a billable code?

Yes. This is a billable ICD-10-CM code, specific enough to report underdosing of digestants, initial encounter on HIPAA-covered claims from October 1, 2025 through September 30, 2026.

What does the 7th character A in T47.5X6A mean?

The final character A marks the initial encounter: use it while the patient is receiving active treatment for underdosing of digestants, such as an emergency visit or first evaluation.

Can T47.5X6A be a principal diagnosis?

No. The Medicare Code Editor rejects this code as a principal diagnosis because underdosing of digestants, initial encounter describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.