2026 ICD-10-CM Diagnosis Code T47.4X5SAdverse effect of other laxatives, sequela
T47.4X5S is a billable ICD-10-CM diagnosis code for adverse effect of other laxatives, sequela. The 7th character S marks it as a sequela code, which reports a problem that remains after the original condition has resolved. It is valid on HIPAA claims for fiscal year 2026 (October 1, 2025 through September 30, 2026) and groups to MS-DRG 922 through 923. The code is not accepted as a principal diagnosis by the Medicare Code Editor and exempt from POA reporting. In AHRQ's Clinical Classifications Software (CCSR), this diagnosis falls under Poisoning/toxic effect/adverse effects/underdosing, sequela.
Code Identity
Code Classification
Code EditsBilling
Medicare Code Editor checks that affect claim validity for T47.4X5S.
Present on Admission (POA)Billing
T47.4X5S is exempt from POA reporting on inpatient claims to general acute care hospitals. Review other POA exempt codes.
Approximate SynonymsGuidance
Alternate terms and clinical phrases that map to this code.
- Adverse reaction to emollient cathartic
- Adverse reaction to glycol
- Adverse reaction to irritant cathartic
- Adverse reaction to oil
- Adverse reaction to polyethylene glycol
- Anthraquinone laxative adverse reaction
- Bulk-forming laxative adverse reaction
- Carmellose adverse reaction
- Cathartic colon
- Cellulose-derived viscosity modifier adverse reaction
- Docusate adverse reaction
- Emollient adverse reaction
- Fixed oil adverse reaction
- Glycerol adverse reaction
- Hydroxyethylcellulose adverse reaction
- Intolerance to drug
- Intolerance to glycerol
- Laxative adverse reaction
- Liquid paraffin adverse reaction
- Magnesium sulfate adverse reaction
- Olive oil adverse reaction
- Paraffin adverse reaction
- Viscosity modifier adverse reaction
Coding GuidelinesGuidance
When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.
The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of agents primarily affecting the gastrointestinal system (T47). Use the following options for the applicable episode of care:
- A - initial encounter
- D - subsequent encounter
- S - sequela
Source: ICD-10-CM Official Guidelines for Coding and Reporting, FY 2026, published by CMS and the National Center for Health Statistics.
Clinical ClassificationClinical
AHRQ’s CCSR groups this code into broader clinical categories.
Clinical InformationClinical
Carbohydrate Binding Modules
contiguous amino acid sequences within a carbohydrate-active enzyme with discrete folds having carbohydrate binding activity. they are classified into 43 different families based on amino acid sequence, binding specificity, and structure.Carboxymethylcellulose Sodium
a cellulose derivative which is a beta-(1,4)-d-glucopyranose polymer. it is used as a bulk laxative and as an emulsifier and thickener in cosmetics and pharmaceuticals and as a stabilizer for reagents.Cellulose
a polysaccharide with glucose units linked as in cellobiose. it is the chief constituent of plant fibers, cotton being the purest natural form of the substance. as a raw material, it forms the basis for many derivatives used in chromatography, ion exchange materials, explosives manufacturing, and pharmaceutical preparations.Cellulose 1,4-beta-Cellobiosidase
an exocellulase with specificity for the hydrolysis of 1,4-beta-d-glucosidic linkages in cellulose and cellotetraose. it catalyzes the hydrolysis of terminal non-reducing ends of beta-d-glucosides with release of cellobiose.Cellulose, Oxidized
a cellulose of varied carboxyl content retaining the fibrous structure. it is commonly used as a local hemostatic and as a matrix for normal blood coagulation.Collodion
a nitrocellulose solution in ether and alcohol. collodion has a wide range of uses in industry including applications in the manufacture of photographic film, in fibers, in lacquers, and in engraving and lithography. in medicine it is used as a drug solvent and a wound sealant.Electrophoresis, Cellulose Acetate
electrophoresis in which cellulose acetate is the diffusion medium.Methylcellulose
methylester of cellulose. methylcellulose is used as an emulsifying and suspending agent in cosmetics, pharmaceutics and the chemical industry. it is used therapeutically as a bulk laxative.alpha-Chlorohydrin
a chlorinated propanediol with antifertility activity in males used as a chemosterilant in rodents.Glycerol
a trihydroxy sugar alcohol that is an intermediate in carbohydrate and lipid metabolism. it is used as a solvent, emollient, pharmaceutical agent, or sweetening agent.Glycerol Kinase
an enzyme that catalyzes the formation of glycerol 3-phosphate from atp and glycerol. dihydroxyacetone and l-glyceraldehyde can also act as acceptors; utp and, in the case of the yeast enzyme, itp and gtp can act as donors. it provides a way for glycerol derived from fats or glycerides to enter the glycolytic pathway. ec 2.7.1.30.Glycerol-3-Phosphate Dehydrogenase (NAD+)
an nad-dependent enzyme that catalyzes the oxidation of sn-glycerol 3-phosphate to glycerone phosphate.Glycerol-3-Phosphate O-Acyltransferase
an enzyme that transfers acyl groups from acyl-coa to glycerol-3-phosphate to form monoglyceride phosphates. it acts only with coa derivatives of fatty acids of chain length above c-10. also forms diglyceride phosphates. ec 2.3.1.15.Glycerolphosphate Dehydrogenase
an enzyme that transfers acyl groups from acyl-coa to glycerol-3-phosphate to form monoglyceride phosphates. it acts only with coa derivatives of fatty acids of chain length above c-10. also forms diglyceride phosphates. ec 2.3.1.15.Glycerophosphates
any salt or ester of glycerophosphoric acid.Glyceryl Ethers
compounds in which one or more of the three hydroxyl groups of glycerol are in ethereal linkage with a saturated or unsaturated aliphatic alcohol; one or two of the hydroxyl groups of glycerol may be esterified. these compounds have been found in various animal tissue.Glycerylphosphorylcholine
a component of phosphatidylcholines or lecithins, in which the two hydroxy groups of glycerol are esterified with fatty acids. (from stedman, 26th ed)Guaifenesin
an expectorant that also has some muscle relaxing action. it is used in many cough preparations.Monoacylglycerol Lipases
an enzyme that catalyzes the hydrolysis of glycerol monoesters of long-chain fatty acids ec 3.1.1.23.Phosphatidylglycerols
a nitrogen-free class of lipids present in animal and particularly plant tissues and composed of one mole of glycerol and 1 or 2 moles of phosphatidic acid. members of this group differ from one another in the nature of the fatty acids released on hydrolysis.Phospholipid Ethers
phospholipids which have an alcohol moiety in ethereal linkage with a saturated or unsaturated aliphatic alcohol. they are usually derivatives of phosphoglycerols or phosphatidates. the other two alcohol groups of the glycerol backbone are usually in ester linkage. these compounds are widely distributed in animal tissues.Teichoic Acids
bacterial polysaccharides that are rich in phosphodiester linkages. they are the major components of the cell walls and membranes of many bacteria.Triolein
(z)-9-octadecenoic acid 1,2,3-propanetriyl ester.Triose Sugar Alcohols
sugar alcohol molecules that contain three carbons.Poloxamer
a nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula ho(c2h4o)a(-c3h6o)b(c2h4o)ah. it is available in different grades which vary from liquids to solids. it is used as an emulsifying agent, solubilizing agent, surfactant, and wetting agent for antibiotics. poloxamer is also used in ointment and suppository bases and as a tablet binder or coater. (martindale the extra pharmacopoeia, 31st ed)L-Iditol 2-Dehydrogenase
an alcohol oxidoreductase which catalyzes the oxidation of l-iditol to l-sorbose in the presence of nad. it also acts on d-glucitol to form d-fructose. it also acts on other closely related sugar alcohols to form the corresponding sugar. ec 1.1.1.14Sorbitol
a polyhydric alcohol with about half the sweetness of sucrose. sorbitol occurs naturally and is also produced synthetically from glucose. it was formerly used as a diuretic and may still be used as a laxative and in irrigating solutions for some surgical procedures. it is also used in many manufacturing processes, as a pharmaceutical aid, and in several research applications.Malvaceae
the mallow family of the order malvales, subclass dilleniidae, class magnoliopsida. the common names of hollyhock and mallow are used for several genera of malvaceae.Sterculia
a plant genus of the family sterculiaceae. s. urens is the source of karaya gum which is sometimes called indian tragacanth, which is different from the true tragacanth which comes from astragalus gummifer.
Table of Drugs and ChemicalsClinical
Substances in the Table of Drugs and Chemicals that reference this code family. Always confirm in the Tabular List before coding.
Patient EducationClinical
Drug Reactions
Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.
The full article covers:
- What is a drug interaction?
- What are side effects?
- What are drug allergies?
- How can I stay safe when taking medicines?
Read the full article at MedlinePlus
Courtesy of MedlinePlus, a service of the U.S. National Library of Medicine.
Convert T47.4X5S to ICD-9-CMHistory
The closest ICD-9-CM equivalents under the General Equivalence Mappings.
Code HistoryHistory
Questions About T47.4X5SOverview
Is T47.4X5S (Adverse effect of other laxatives) a billable code?
Yes. This is a billable ICD-10-CM code, specific enough to report adverse effect of other laxatives, sequela on HIPAA-covered claims from October 1, 2025 through September 30, 2026.
What does the 7th character S in T47.4X5S mean?
The final character S makes this a sequela code: it reports a lingering problem that remains after the adverse effect of other laxatives itself has resolved, not the original event.
What MS-DRG does T47.4X5S group to?
On inpatient claims, adverse effect of other laxatives, sequela maps to MS-DRG 922, 923, with relative weights from 1.0177 to 1.7494 depending on complications. Higher weights mean higher Medicare reimbursement.
Can T47.4X5S be a principal diagnosis?
No. The Medicare Code Editor rejects this code as a principal diagnosis because adverse effect of other laxatives, sequela describes a circumstance that influences health status rather than a current illness. Report it as a secondary diagnosis.
Is T47.4X5S exempt from POA reporting?
Yes. CMS lists this code among those exempt from present on admission reporting, so hospitals do not assign a POA indicator for adverse effect of other laxatives, sequela on inpatient claims.
Footnotes
[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.
